Introducing new functions into (and onto) virus-like particles
July 16-20, 2017
Leviphage Qß and PP7 are well studied viruses that infect E. coli. They also provide highly stable and tailorable capsid protein structures that can be
manipulated in a number of ways by the molecular biologist and chemist. We will describe our work with both particles, designed to give them new binding, shielding, and catalytic properties. This involves the expression of hybrid particles bearing catalytic protein domains on the inside or outside, the use of standard polymerization methods to grow organic polymers from the surface or into the interior of the particles, and the marriage of these particles with degradable hydrogel carriers
Please click Additional Files below to see the full abstract.
M.G. Finn, Liangjun Zhao, Jiri Schimer, Christian Scheibe, and Jason Fiedler, "Introducing new functions into (and onto) virus-like particles" in "Biochemical and Molecular Engineering XX", Wilfred Chen, University of Delaware, USA Nicole Borth, Universität für Bodenkultur, Vienna, Austria Stefanos Grammatikos, UCB Pharma, Belgium Eds, ECI Symposium Series, (2017). http://dc.engconfintl.org/biochem_xx/84