Intelligent hydrogel design: Towards more performing hydrogel processing
June 5-9, 2017
Despite their highly attractive properties, 3D printing of hydrogel materials can be rather challenging. Herein, we present a novel hydrogel material that can be easily processed into three-dimensional scaffolds using different 3D printing technologies. An acrylate-terminated, urethane-based PEG was prepared by reacting PEG 2000 with isophorone diisocyanate (IPDI) and monoacrylated PEG (336 g/mol) in a 1:2:2 molar ratio (WO 2017/005613 A1). For melt 3D-printing, pure polymer was used (Tm 38°C). For bioprinting, a 50 wt% solution with 3 wt% Laponite was used.
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Sandra Van Vlierberghe, Annemie Houben, Jasper Van Hoorick, Aleksandr Ovsianikov, Peter Gruber, Marica Markovic, Penny Martens, Patrice Roose, Dirk Bontinck, Hugues Van Den Bergen, Heidi Declercq, and Peter Dubruel, "Intelligent hydrogel design: Towards more performing hydrogel processing" in "Biofabrication for Hierarchical in Vitro Tissue Models", Jürgen Groll (University of Würzburg, Germany) Jos Malda (University Medical Centre Utrecht, The Netherlands) Eds, ECI Symposium Series, (2017). http://dc.engconfintl.org/biofab_tissue_model/23