Conference Dates

October 18-21, 2015


The E&L profile of Single-Use-Systems (SUS) include base polymers, additives, processing aids, and degradants that could potentially migrate from the container materials to contact solvents. Different conditions (such as temperature, surface area to volume ratio, dynamic/static incubation, and solvents) could produce different E&L profiles. In order to mitigate this problem, the BPOG Extractables Work Group has recently published a standardized extractables protocol recommendation in the form of a white paper (1) that defines sample conditions and analytical procedures for extractable testing.

This presentation will discuss the E&L container film results of an undergoing study preformed following BPOG guidelines compared to the results of previous studies performed under vastly different conditions.