July 23-26, 2017
While passive thermal imaging of temperature difference between tumor and neighboring tissue provides limited contrast, active thermography with external thermal modulation may provide higher contrast presumably due to the distinct thermal response from the tumor tissue. We have investigated physiologically relevant parameters such as response rate with respect to thermal modulation and relaxation time. This new imaging modality in the infrared regime may prove useful as a label-free and non-invasive screening tool. On the other hand, we propose a novel use of controlled thermal injury from non-ablative fractional laser irradiation for early treatment of tumor growth with a fiber-based thulium laser at 1927 nm. We investigated the potential cancer prevention effect with mouse model of early tumor. This laser treatment could potentially be an alternative anticancer modality for early tumorigenesis in a minimally invasive manner.
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Euiheon Chung, Gyungseok Oh, and Su Woong Yoo, "Tumor detection and treatment by means of thermography and laser irradiation" in "Advances in Optics for Biotechnology, Medicine and Surgery XV", Peter So, Massachusetts Institute of Technology, USA Kate Bechtel, Triple Ring Technologies, USA Ivo Vellekoop, University of Twente, The Netherlands Michael Choma, Yale University, USA Eds, ECI Symposium Series, (2017). http://dc.engconfintl.org/biotech_med_xv/10