In-vitro validation and quantitative measurements of graded burn wounds on a porcine model using handheld laser speckle imaging
July 23-26, 2017
Burn wound severity can be difficult to assess and the diagnosis is usually subjective. Optical techniques have emerged as alternative methods for providing objective, non-contact assessment of burn wound severity. One such technique is Laser Speckle Imaging (LSI), which quantifies superficial blood flow using coherent laser light.
We have previously demonstrated that LSI can be used to accurately assess burn wounds. However, LSI is conventionally used in static designs, such as cart-based or tripod mounted configurations, due to the susceptibility of LSI to motion artifact. This can limit the portability and usability of the device in a clinical. Handheld LSI can potentially overcome these limitations. However, accounting for motion artifact associated with user movement must be addressed to obtain accurate and reliable blood flow measurements.
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Ben Lertsakdadet, Bernard Choi, Anthony J. Durkin, Rebecca Rowland, Christian Crouzet, Cody E. Dunn, Adrien Ponticorvo, Bruce Y. Yang, and Nicole Bernal, "In-vitro validation and quantitative measurements of graded burn wounds on a porcine model using handheld laser speckle imaging" in "Advances in Optics for Biotechnology, Medicine and Surgery XV", Peter So, Massachusetts Institute of Technology, USA Kate Bechtel, Triple Ring Technologies, USA Ivo Vellekoop, University of Twente, The Netherlands Michael Choma, Yale University, USA Eds, ECI Symposium Series, (2017). http://dc.engconfintl.org/biotech_med_xv/2