New application of transglucosidase with α-glucosidase inhibitor in the digestive tract
September 24-28, 2017
We have studied transglucosidase derived from Aspergillus niger for self-mediation in the gastrointestinal tract as a dietary supplement. This enzyme is very popular to produce oligosaccharides in industry.
Prof. Sasaki already reported this enzyme showed oligosaccharides production in the digestive tract which improved microflora level in large intestine and decreased the blood glucose level and the excretion of insulin.
The clinical study of this enzyme was performed in 21 healthy volunteers and patients with type 2 diabetes mellitus to check the glucose level in blood and secretion of insulin after meal. This enzyme showed good improvement in biological parameters.
Please click Additional Files below to see the full abstract.
Yoshihiko Hirose, "New application of transglucosidase with α-glucosidase inhibitor in the digestive tract" in "Enzyme Engineering XXIV", Pierre Monsan, Toulouse White Biotechnology, France Magali Remaud-Simeon, LISBP-INSA, University of Toulouse, France Eds, ECI Symposium Series, (2017). http://dc.engconfintl.org/enzyme_xxiv/113