Enzymatic glycosylation of Ellagic acid

Conference Dates

September 24-28, 2017


Ellagic acid is a natural biomolecule with several biological propertiesi such as anti-oxidant activity. However the poor solubility of this compound limits its bioavailability and its potential for pharmaceutical or cosmetic application.ii It’s well-known that glycosylation can significantly improve the physicochemical and biological properties of small molecules.iii Enzymatic glycosylation of this compound would be a solution to access a more soluble ellagic acid through a sustainable and environmentally friendly process. Glucansucrases, that use sucrose as donor substrate to transfer a glucose unit, are highly promising catalysts to glycosylate high valuated biomolecules.iv

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