Title
Pilot scale implementation of a single-use, high intensity, integrated process system
Conference Dates
September 23-26, 2018
Abstract
Pfizer and Boehringer Ingelheim are developing pilot scale systems with entirely single-use flow paths that are fully integrated end-to-end under a single control system from bioreactor through downstream processing. These prototype systems are designed to run continuous processing from the bioreactor to downstream, and periodic processing to the end of the downstream system. This presentation shows the evolution of the systems including some novel single use technologies, details of some high-intensity run results, and offers future single use improvement ideas.
Recommended Citation
Robert Kottmeier, John Galyas, Phil McCormick, Michael O’Connor, and David Sullivan, "Pilot scale implementation of a single-use, high intensity, integrated process system" in "Single-Use Technologies III: Scientific and Technological Advancements", Weibing Ding, Amgen Martina Micheletti, University College London Robert Repetto, Pfizer Eds, ECI Symposium Series, (2018). https://dc.engconfintl.org/sut_iii/48