Matrix approach of Full-Field OCT for volumetric imaging of an opaque human cornea
June 2-6, 2019
Optical microscopy offers the possibility to image biological tissue with a diffraction limited resolution (~µm). However, the heterogeneity of biological tissues can strongly affect light propagation at large depths by distorting the initial wavefront. Large and short range fluctuations of the refractive index can induce aberration and multiple scattering, respectively. Inspired by a recent work , we have developed a matrix approach to Full-Field Optical Coherence Tomography (FF-OCT) to push back the fundamental limit of aberrations and multiple scattering. Here, we report on the application of this approach to the imaging of the human cornea and the quantitative measurement of the corneal transparency.
Please click Additional Files below to see the full abstract.
Paul Balondrade, Victor Barolle, Claude Boccara, Mathias Fink, Alexandre Aubry, Ulysse Najar, and Kristina Irsch, "Matrix approach of Full-Field OCT for volumetric imaging of an opaque human cornea" in "Advances in Optics for Biotechnology, Medicine and Surgery XVI", Erin Buckley, Emory University/Georgia Institute of Technology, USA Christophe Moser, Polytechnique Fédérale de Lausanne (EPFL), Switzerland Brian Pogue, Dartmouth College, USA David Sampson, University of Western Australia, Australia Eds, ECI Symposium Series, (2019). https://dc.engconfintl.org/biotech_med_xvi/15