Monitor and control of multiple bioreactor parameters using in situ raman spectroscopy

Conference Dates

May 6-11, 2018


In situ Raman spectroscopy allows bioreactor parameters to be automatically measured online, multiple times per hour, while eliminating the need for sample removal. Raman spectra are used to develop predictive models for real-time measure of cell culture parameters. These models have been employed in development for superior process control of upstream bioprocesses. A case study of our approach will be discussed.

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