Ceramic composite bone tissue scaffolds
November 10-14, 2019
The repair of broken or diseased bone tissue requires a multitude of strategies ranging from allografts to bone substitutes. Herein we describe a process to create porous all-ceramic scaffolds for bone tissue repair without the need for typical ceramics processing techniques for consolidation (see Figure 1)—a technique that has potential to be used in situ in the operating theatre or in the field. The process uses room temperature and pressure to elicit a reaction within a liquid ceramic precursor to form a silicate-glass binder phase to consolidate bioactive glass frit (of the 45S5 composition). Morphological characterization and mechanical response of the composite scaffolds is reviewed paying credence to design specifications required in biomedical implant materials, such as: formability, structural integrity, porosity, load-bearing capability, bioactivity, and resorbability.
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John A. Nychka and Caitlin M. Guzzo, "Ceramic composite bone tissue scaffolds" in "Composites at Lake Louise 2019", John Kieffer, University of Michigan, USA Erik Spoeke, Sandia National Laboratories, USA Meisha Shofner, Georgia Institution of Technology, USA Eds, ECI Symposium Series, (2019). https://dc.engconfintl.org/composites_all_2019/35