The development of new biocatalytic reactions for organic synthesis
September 15-19, 2019
This lecture will describe recent work from our laboratory aimed at developing new biocatalysts for enantioselective organic synthesis, with emphasis on the design of in vitro and in vivo cascade processes for generating chiral pharmaceutical building blocks. By applying the principles of ‘biocatalytic retrosynthesis’ we have shown that it is increasingly possible to design new synthetic routes to target molecules in which biocatalysts are used in the key bond forming steps .
Please click Additional Files below to see the full abstract.
Nicholas Turner, "The development of new biocatalytic reactions for organic synthesis" in "Enzyme Engineering XXV", Huimin Zhao, University of Illinois at Urbana-Champaign, USA John Wong, Pfizer, USA Eds, ECI Symposium Series, (2019). https://dc.engconfintl.org/enzyme_xxv/148