In silico approach to better understand the role of active site residue

Conference Dates

September 15-19, 2019


Chiral amines are the major building blocks of many life-saving drugs and it has been estimated that nearly 40-45% of the currently used pharmaceuticals contain chiral amine functional groups in their structure. However, the major challenges associated with the chemical synthesis of enantiopure amines are the use of toxic chemicals, formation of many by-products, and multi-step synthesis process. To address these limitations, cost-effective biocatalytic methods are emerging as potential alternatives for the synthesis of chiral amines in enantiomerically pure forms.

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