pH-responsive microcapsules synthesized via a water-in-oil-in-water emulsion template

Conference Dates

April 3-7, 2016


Biological agents, such as peptides and nucleic acids (siRNA or dsRNA), are becoming increasingly employed in both the therapeutic and agrochemical industries as alternatives to synthetic chemicals. These agents have a number of advantages, including their specificity for a target, ease of registration and low human toxicity.1 Chemical pesticides are currently the most common method of crop protection, but have a number of drawbacks including their toxicity and effects on non-target species.2 Therefore, there is an ever-shifting move to the use of more eco-friendly biological control measures; however, these also have negative attributes.

Bio-control agents are often unstable3 and, upon ingestion, are subjected to degradation by hydrolytic enzymes and conditions favouring acid hydrolysis. As a result, these water soluble agents must be protected by encapsulation in a water continuous phase. This provides a protective shell, ensuring their stability during delivery and giving the ability to control and trigger release, which facilitates a more efficient use.

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