Organic-inorganic magnetic hybrids as multifunctional imaging and therapeutic agents
July 3-7, 2016
Magnetic iron oxide nanoparticles (SPIONs) have become key elements in the design of functional nanostructures able to play an active role in different biomedical applications, e. g. as heat generating nanosources in magnetic hyperthermia, as contrast agents in magnetic resonance imaging (MRI), in drug delivery and cell separation, and in biosensing. On the other hand, polymeric nanostructures have received great interest as suitable bioactive encapsulating agents and carriers due to their biocompatibility, low toxicity and ability to influence the bioactive delivery profile . In a further step, hybrid organic-inorganic nanocomposites have been explored as a synergistic approach that combines the modified bioactive release induced by the polymer/lipid encapsulation and the intrinsic physico-chemical properties from the inorganic counterpart . In particular, magnetic hybrid self-assemblies have been found to open new perspectives for biomedical and environmental applications [3, 4].
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M. Bañobre-López, C. L. Moura, J. Gallo, N. M. P. S. Ricardo, and N. J. Long, "Organic-inorganic magnetic hybrids as multifunctional imaging and therapeutic agents" in "Nanotechnology in Medicine: From Molecules to Humans", Prof. Lola Eniola-Adefeso, Department of Chemical Engineering, University of Michigan, USA Prof. Paolo Decuzzi, Italian Institute of Technology, Italy Eds, ECI Symposium Series, (2016). https://dc.engconfintl.org/nanotech_med/39