Towards a platform process for the manufacture of glycoconjugate vaccines for pneumococcal disease

Conference Dates

June 12 – 17, 2022


Streptococcus pneumoniae (S. pneumoniae) is one of the leading causes of invasive bacterial disease in children where infection results in pneumonia and meningitis. The introduction of glycoconjugate vaccines for the bacterium has meant a significant reduction in cases of invasive bacterial diseases in children under the age of 5 worldwide. The current gold standard glycoconjugate vaccine for immunization is Prevenar-13. However, a currently complex and long manufacturing process involving chemical conjugation means the final cost per dose of the vaccine is high.

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