July 16-20, 2017
The Duke Marriott Newport Beach
Newport Beach, CA, USA
| Editors: | Wilfred Chen, University of Delaware, USA |
|---|---|
| Nicole Borth, Universität für Bodenkultur, Vienna, Austria | |
| Stefanos Grammatikos, UCB Pharma, Belgium |
The articles for these proceedings are not peer-reviewed.
Sustainable production of industrially relevant biomonomers: A photosynthetic consortia approach, David N. Carruthers and Xiaoxia Nina Lin (Abstract)
The microbial antibodies secretion expression platform with scale down fermentors, Jen-Wei Chang, Wei-Kuang Chi, Neng-Hsien Chang, Wei-Hong Chen, Yi-Hua Huang, and Chih-Hsi Fan (Abstract and Presentation)
The simplex algorithm in an automated high-throughput approach for the rapid screening of operating conditions during process understanding and development, Razwan Hanif, Mariangela Spitali, and Stefanos Grammatikos (Abstract)
Novel clone selection technique reveals heterogeneity among HEK293T cells engineered to produce therapeutic extracellular vesicles, Jeffrey Chalmers, Eric Plencner, Xiaohua Zhu, Amaya Peter, Jinmai Jiang, Derek Hansford, Thomas D. Schmittgen, and Mitch Phelps (Abstract)
Investigating antibody reduction phenomenon observed in large scale cell culture harvests using a simple scale down model, Shaunak D. Uplekar, Tim Broderick, Niket Bubna, Kaitlyn Hall, Nate Oien, Sigma Mostafa, and Abhinav Shukla (Abstract)
Generation of a Chinese Hamster Ovary cell genome-wide deletion library, Valerie Schmieder, Vaibhav Jadhav, Helene Faustrup Kildegaard, and Nicole Borth (Abstract)
Host cell protein control via CHO genome engineering, Jong Youn Baik and Kelvin H. Lee (Abstract)
Transcriptomic signatures classifying CHO Quasispecies, Ankita Singh, Helene F. Kildegaard, and Mikael R. Andersen (Abstract)
Role of CD36 and free fatty acid uptake in epithelial-mesenchymal transition of hepatocellular carcinoma cells, Christina Chan (Abstract)
Optimizing a bacterial sRNA scaffold for targeting multiple mRNAs, filtering off- target mRNA interactions, and balancing metabolic pathway flux, Richard A. Lease, David W. Wood, Hopen Yang, Ashwin Lahiry, and Samuel D. Stimple (Abstract)
Deciphering ambiguous control over fluxes through characterization and reduction of uncertainty, Ljubisa Miskovic, Jonas Beal, Michael Moret, and Vassily Hatzimanikatis (Article)
Risk mitigation and resource savings for biological drug product with computational fluid dynamics simulation, Weixian Shi (Abstract)
Molecular modeling on HIF2α-ARNT dimer destabilization caused by HIF2α V192D and/or R171A mutations, Chia-Ning Yang and Ya-Jyun Chen (Abstract)
REMI: Constraint-based method for integrating relative expression and relative metabolite levels into a thermodynamically consistent metabolic model, Vikash Pandey and Vassily Hatzimanikatis (Abstract)
Generation and analysis of large-scale dynamic nonlinear models of metabolism, Georgios Fengos, Vassily Hatzimanikatis, and Ljubisa Miskovic (Article)
Investigating crowded metabolism: A molecular particle approach, Daniel Robert Weilandt and Vassily Hatzimanikatis (Article)
Functional adaptation of mercuric reductases from the deep brine environment of Atlantis II in the Red Sea to high temperature, Mohamad Maged and Hamza El dorry (Abstract)
Characterization of a renoprotective AATF peptide in models of diabetic nephropathy, Qing Guo, Jun Xie, and Jian-xing Ma (Abstract)
Antibody engineering on the surface of CHO cells, Annalee W. Nguyen and Jennifer Maynard (Abstract)
Context-specific cell signaling analysis using logic framework, Vikash Pandey and Vassily Hatzimanikatis (Abstract)
Strategies to engineer G protein-coupled receptor ligand binding properties, Justin I. Yoo, Patrick Daugherty, and Michelle O’Malley (Abstract)
Effects of the A2AR C-terminus on receptor stability, Kirsten N. Swonger and Annie Tir (Abstract)
Intracellular secretion analysis of therapeutic antibodies in engineered high- producible CHO cells, Kohei Kaneyoshi, Takeshi Omasa, Yuichi Koga, Noriko Yamano, Keiji Uchiyama, and Masayoshi Onitsuka (Abstract)
A CRISPR/Cas9 based engineering tool to activate expression of multiple genes individually or in any specific combination, Peter Eisenhut, Gerald Klanert, Marcus Weinguny, Nicole Borth, and Daniel Ivansson (Abstract)
Engineering the microbiota to treat metabolic disorders, Nikhil U. Nair, Zachary J. S. Mays, and Josef R. Bober (Abstract)
Programmable control of CRISPR-Cas9 systems by engineering sgRNA as toehold- switchable riboregulators, Ka-Hei Siu and Wilfred Chen (Abstract)
Exploring chemodiversity in metabolism towards the selective integration of chemistry into biology, Jasmin Hafner, Noushin Hadadi, and Vassily Hatzimanikatis (Article)
Toward the identification of new cancer therapy targets using metabolic modeling in a human genome scale, Maria Masid, Meric Ataman, Georgios Fengos, and Vassily Hatzimanikatis (Article)
Modeling and analysis of ArsR genetic circuits, Yves Berset, Vassily Hatzimanikatis, Davide Merulla, Jan Roelof van der Meer, and Aurélie Joublin (Article)
Sort-seq approach to engineering an E. coli formaldehyde-inducible promoter, Julia Rohlhill, Eleftherios T. Papoutsakis, and Nicholas R. Sandoval (Abstract)
Functional production of transporters from biomass-degrading anaerobic fungi for metabolic engineering, Susanna Seppala, Justin Yoo, Michelle O’Malley, Igory Podolsk, and Daniel Yur (Abstract)
Design considerations to ensure accuracy when using the resazurin reduction assay to noninvasively quantify cell expansion within perfused extracellular matrix scaffolds, William , M. Miller; Joseph S. Uzarski; Michael D. DiVito; and Jason A. Wertheim (Abstract)
Isolation and characterization of cancer stem cells in esophagus squamous cell carcinoma, Pei-Jung Lu (Abstract)
Engineering T cell receptors for improved therapeutic T regulatory cell (Treg) function, Elissa K. Leonard and Jennifer Maynard (Abstract)
Overcoming challenges in the production of Hepatitis C virus like particles, Manuel Carrondo, Hugo Soares, Rute Castro, Ana Isabel Almeida, and Ana Sofia Coroadinha (Abstract)
Next-generation antibody and TCR therapeutics for infectious disease, Ellen . K. Wagner, Ahlam Qerqez, Annalee Nguyen, and Jennifer Maynard (Abstract)
Toward the identification of cellular mechanisms behind the lethal phenotypes in malaria parasites blood stages with PlasmoGEM and metabolic modeling, Anush Chiappino-Pepe, Vassily Hatzimanikatis, Ellen Bushell, Julian C. Rayner, and Oliver Billker (Article)
Engineering the adenylate cyclase toxin for use as a bordetella pertussis vaccine antigen, Andrea M. DiVenere (Abstract)