Overcoming the challenges of freeze-drying biological drugs in unit-dose formats: Transitioning from batch to continuous processing

Authors

• Robert Pisano, Politecnico di Torino, ItalyFollow
• Steven J. Burcat, Department of Mechanical Engineering, Massachusetts Institute of Technology, USA
• Bernhardt L. Trout, Department of Mechanical Engineering, Massachusetts Institute of Technology, USA
• Alexander H. Slocum, Department of Mechanical Engineering, Massachusetts Institute of Technology, USA
• Richard D. Braatz, Department of Mechanical Engineering, Massachusetts Institute of Technology, USA
• Rohan P. Kadambi, Department of Mechanical Engineering, Massachusetts Institute of Technology, USA
• Lorenzo Stratta, Department of Applied Science and Technology, Politecnico di Torino, Italy

Conference Dates

October 5-9, 2025

Abstract

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Recommended Citation

Robert Pisano, Steven J. Burcat, Bernhardt L. Trout, Alexander H. Slocum, Richard D. Braatz, Rohan P. Kadambi, and Lorenzo Stratta, "Overcoming the challenges of freeze-drying biological drugs in unit-dose formats: Transitioning from batch to continuous processing" in "Integrated Continuous Biomanufacturing VII (ICB VII)", Irina Ramos, AstraZeneca; Mark Brower, Merck; Alois Jungbauer, BOKU; K. Brower, Sanofi Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/biomanufact_vii/92