Monitoring recombinant adeno-associated virus production in mammalian cell cultures via single-cell biophysical profiling and machine learning

Authors

• Francesco Destro, Massachusetts Institute of Technology, USAFollow
• Weida Wu, Massachusetts Institute of Technology
• John Joseph, Massachusetts Institute of Technology
• Paul W. Barone, Massachusetts Institute of Technology
• Stacy L. Springs, Massachusetts Institute of Technology
• Anthony J. Sinskey, Massachusetts Institute of Technology
• Richard D. Braatz, Massachusetts Institute of Technology
• Scott R. Manalis, Massachusetts Institute of Technology
• Amogh Morje, Massachusetts Institute of Technology

Conference Dates

April 27 - May 2, 2025

Abstract

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Recommended Citation

Francesco Destro, Weida Wu, John Joseph, Paul W. Barone, Stacy L. Springs, Anthony J. Sinskey, Richard D. Braatz, Scott R. Manalis, and Amogh Morje, "Monitoring recombinant adeno-associated virus production in mammalian cell cultures via single-cell biophysical profiling and machine learning" in "Cell Culture Engineering XIX", A Khetan, BMS; Marcella Yu, Gilead; Mike Betenbaugh, Johns Hopkins University Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/cell_culture_engineering_xix/142