Simultaneous enhancement in AAV productivity and particle quality in batch and perfusion cultures of producer cell lines through systems approach

Authors

• Madhuresh Sumit, Sanofi, USAFollow
• Nipun Goel, GMU Cell Culture Process Development, Sanofi, Waltham, MA, USA
• Daniel Furey, GMU Cell Culture Process Development, Sanofi, Waltham, MA, USA
• Olivia Tsang, GMU Cell Culture Process Development, Sanofi, Waltham, MA, USA
• Rachel Sun, GMU Cell Culture Process Development, Sanofi, Waltham, MA, USA
• Yingchao Nie, GMU Pre-Development, Sanofi, Waltham, MA, USA
• Karen Vincent, Genomic Medicine Unit CMC, Sanofi, Waltham, MA, USA
• Jeong Lee, GMU Cell Culture Process Development, Sanofi, Waltham, MA, USA
• Bruno Figueroa, Genomic Medicine Unit CMC, Sanofi, Waltham, MA, USA

Conference Dates

April 27 - May 2, 2025

Abstract

Please click Additional Files below to see the full abstract

Recommended Citation

Madhuresh Sumit, Nipun Goel, Daniel Furey, Olivia Tsang, Rachel Sun, Yingchao Nie, Karen Vincent, Jeong Lee, and Bruno Figueroa, "Simultaneous enhancement in AAV productivity and particle quality in batch and perfusion cultures of producer cell lines through systems approach" in "Cell Culture Engineering XIX", A Khetan, BMS; Marcella Yu, Gilead; Mike Betenbaugh, Johns Hopkins University Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/cell_culture_engineering_xix/162