Interplay between amino acid depletions, Sequence variants and other product quality attributes in a bispecific mAb: A case study

Authors

• Nancy Guillen, Protein Therapeutics API, J&J Innovative Medicine, USAFollow
• Nantiya Moonwong Abraham, Protein Therapeutics API, J&J Innovative Medicine
• Jason Chen, Protein Therapeutics API, J&J Innovative Medicine
• Pushpraj Rana, Protein Therapeutics API, J&J Innovative Medicine
• Nicole Larmore, Protein Therapeutics API, J&J Innovative Medicine
• Fang Qian, Material Sciences, J&J Innovative Medicine
• Adam Evans, Biologics Analytical Development, J&J Innovative Medicine

Conference Dates

April 27 - May 2, 2025

Abstract

Please click Additional Files below to see the full abstract

Recommended Citation

Nancy Guillen, Nantiya Moonwong Abraham, Jason Chen, Pushpraj Rana, Nicole Larmore, Fang Qian, and Adam Evans, "Interplay between amino acid depletions, Sequence variants and other product quality attributes in a bispecific mAb: A case study" in "Cell Culture Engineering XIX", A Khetan, BMS; Marcella Yu, Gilead; Mike Betenbaugh, Johns Hopkins University Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/cell_culture_engineering_xix/237