Doubling recombinant protein productivity in CHO cells and altering glycosylation profiles by modulating underexplored autophagy and cellular growth mechanisms

Authors

• Sri Madabhushi, Merck & Co., Inc., USAFollow
• Ansuman Sahoo, Biologics Process Research and Development, Merck & Co., USA
• Tomas Kasza, Biologics Process Research and Development, Merck & Co., USA
• Tomali Chakravarty, Biologics Process Research and Development, Merck & Co., USA
• Taku Tsukidate, Analytical Research and Development, Merck & Co., Inc., USA
• Xuanwen Li, Analytical Research and Development, Merck & Co., Inc., USA

Conference Dates

April 27 - May 2, 2025

Abstract

Please click Additional Files below to see the full abstract

Recommended Citation

Sri Madabhushi, Ansuman Sahoo, Tomas Kasza, Tomali Chakravarty, Taku Tsukidate, and Xuanwen Li, "Doubling recombinant protein productivity in CHO cells and altering glycosylation profiles by modulating underexplored autophagy and cellular growth mechanisms" in "Cell Culture Engineering XIX", A Khetan, BMS; Marcella Yu, Gilead; Mike Betenbaugh, Johns Hopkins University Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/cell_culture_engineering_xix/239