Optimization of multispecific antibody production: the impact of vector topology, ratio, and selection strategies for improved productivity and quality

Authors

• José Escandell, IBET, PortugalFollow
• Sara . Maimouni, Sanofi CMC Development, Framingham, USA
• Catarina Melo, iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal;
• Mariana Antunes, iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal;
• Jose Escandell, iBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal;
• Michael . Hoffman, Sanofi CMC Development, Framingham, USA
• Patrícia Gomes-Alves, iBET, Instituto de Biologia Experimental e Tecnológica, Portugal;
• Jack . Scarcelli, Sanofi CMC Development, Framingham, USA

Conference Dates

April 27 - May 2, 2025

Abstract

Please click Additional Files below to see the full abstract

Recommended Citation

José Escandell, Sara . Maimouni, Catarina Melo, Mariana Antunes, Jose Escandell, Michael . Hoffman, Patrícia Gomes-Alves, and Jack . Scarcelli, "Optimization of multispecific antibody production: the impact of vector topology, ratio, and selection strategies for improved productivity and quality" in "Cell Culture Engineering XIX", A Khetan, BMS; Marcella Yu, Gilead; Mike Betenbaugh, Johns Hopkins University Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/cell_culture_engineering_xix/249