Title
Metabolite-based model predictive control of cell growth
Conference Dates
January 27-31, 2019
Abstract
Batch-to-batch variation causes significant challenges in the production of cell and gene therapies in terms of manufacturing planning and process comparability. Since the processes deal with living systems that are complex and time-varying, remediating process variability requires dynamic control over the Critical Process Parameters.
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Recommended Citation
Kathleen Van Beylen, Ali Youssef, Jean-Marie Aerts, Toon Lambrechts, and Ioannis Papantoniou, "Metabolite-based model predictive control of cell growth" in "Advancing Manufacture of Cell and Gene Therapies VI", Dolores Baksh, GE Healthcare, USA Rod Rietze, Novartis, USA Ivan Wall, Aston University, United Kingdom Eds, ECI Symposium Series, (2019). https://dc.engconfintl.org/cell_gene_therapies_vi/21