Scalable allogeneic CAR-T manufacturing: Perfusion optimization, multi- liter scale-up and automated harvesting in single-use stirred-tank bioreactors

Authors

Pierre Springuel, University College London, United KingdomFollow
Tiffany Hood, University College London
Fern Slingsby, The Automation Partnership (Cambridge), Sartorius UK
Nicola Bevan, Sartorius UK
Amanda Frangleton, Sartorius UK
Timo Schmidberger, Sartorius Stedim Biotech GmbH
Winfried Geis, Sartorius Stedim Biotech GmbH
Julia Hengst, Sartorius Stedim Biotech GmbH
Noushin . Dianat, Sartorius Stedim France S.A.S
Qasim Rafiq, University College London

Conference Dates

February 4 - 8, 2024

Abstract

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Recommended Citation

Pierre Springuel, Tiffany Hood, Fern Slingsby, Nicola Bevan, Amanda Frangleton, Timo Schmidberger, Winfried Geis, Julia Hengst, Noushin . Dianat, and Qasim Rafiq, "Scalable allogeneic CAR-T manufacturing: Perfusion optimization, multi- liter scale-up and automated harvesting in single-use stirred-tank bioreactors" in "Advancing Manufacture of Cell and Gene Therapies VIII", Fernanda Masri, Cytomos, United Kingdom; Carolyn Yeago, CY Solutions LLC, USA; Gargi Maheshwari, BMS, USA; John Moscariello, BMS, USA Eds, ECI Symposium Series, (2024). https://dc.engconfintl.org/cell_gene_therapies_viii/90