Title
Deterministic cell processing recovers >2-fold more cells, and up to 5-fold more naïve T cells, as compared to centrifugally prepared cells
Conference Dates
February 6 – 10, 2022
Abstract
There are still significant manufacturing challenges impeding the rapid adoption of advanced therapies. The first day of leukapheresis product processing typically requires ~5 steps (~4-6 hours) and incurs significant cell loss prior to cell selection and/or activation steps. Here, we present data from our Curate® cell processing system, a single step process that yields >2 fold more cells with comparable or better quality in under an hour.
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Recommended Citation
Tony Ward, Yasna Behmardi, Laurissa Ouaguia, Cole Jones, Hani Rahmo, Alison Skelley, Khushroo Gandhi, and Roberto Campos-Gonzalez, "Deterministic cell processing recovers >2-fold more cells, and up to 5-fold more naïve T cells, as compared to centrifugally prepared cells" in "Advancing Manufacture of Cell and Gene Therapies VII", Sharon Brownlow, Cell & Gene Therapy Catapult, UK; Sean Palecek, University of Wisconsin, USA; Damian Marshall, Achilles Therapeutics, UK; Fernanda Masri, Cell & Gene Therapy Catapult, UK Eds, ECI Symposium Series, (2022). https://dc.engconfintl.org/cellgenetherapies_vii/7