Title
Improved biomass conversion with Trichoderma reesei beta-glucosidase Cel3A engineered for broader substrate specificity
Conference Dates
September 15-19, 2019
Abstract
Fungal cellulolytic enzyme cocktails are widely used for the hydrolysis of biomass into fermentable sugars. Beta-Glucosidases enhance enzymatic biomass conversion by relieving cellobiose inhibition of endoglucanases and cellobiohydrolases. Fungal GH3 beta-glucosidases are often specific for hydrolysis of pyranose glycosides and severely inhibited by monomeric glucose.
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Recommended Citation
Thijs Kaper, Amy Liu, Brad Kelemen, Zach Beck, Pim van der Kley, Slavko Kralj, Henrik Hansson, Mats Sandgren, and Nils Mikkelsen, "Improved biomass conversion with Trichoderma reesei beta-glucosidase Cel3A engineered for broader substrate specificity" in "Enzyme Engineering XXV", Huimin Zhao, University of Illinois at Urbana-Champaign, USA John Wong, Pfizer, USA Eds, ECI Symposium Series, (2019). https://dc.engconfintl.org/enzyme_xxv/23