April 3 – 7, 2022
Albufeira, Portugal
| Chairs: | Barry Buckland, BiologicB, USA |
|---|---|
| Eli Keshavarz-Moore, University College London, UK |
The articles for these proceedings are not peer-reviewed.
Microbial Engineering II, Barry Buckland and Eli Keshavarz-Moore (Article)
Engineering Microbial systems: potential to enable affordable and accessible interventions for global health, Stephen Hadley (Abstract)
Refactoring yeast central metabolism to reverse growth phenotypes and Product formation, Diethard Mattanovich (Abstract)
Valorization of renewables into bio-based chemicals using metabolically engineered microbes, Christoph Wittmann (Abstract)
Microbial engineering of new Streptomyces sp. from extreme environments for novel antibiotics, anticancer and antifungal Drugs, Juan Asenjo, Valeria . Razmilic, Diego Lagos, Scott Jarmusch, and Barbara Andrews (Abstract and Presentation)
Pollution to products: Recycling of “above ground” carbon by gas fermentation, Michael Koepke (Abstract)
Klebsiella pneumoniae as cell factory for chemicals production, Frank Baganz, Jian Hao, and Gary Lye (Abstract and Presentation)
Fermented pheromones – a sustainable solution for plant protection from insect pests, Irina Borodina (Abstract)
Expanding understanding and scope of Pichia pastoris for secreted protein expression, Nico Callewaert (Abstract)
Pichia production host engineering by systemic host changes, Christoph Kiziak, Núria Adelantado, Jennifer Staudacherb, Corinna Rebneggerb, Brigitte Gasserbc, and Diethard Mattanovich (Abstract)
Flo8 – A versatile regulator for improving recombinant protein production in Pichia pastoris, Brigitte Gasser, Corinna Rebnegger, Diethard Mattanovich, Viktoria Kowarz, and Mirelle Flores (Abstract)
Characterization of homologous industrial strains using continuous cultivation techniques to understand process performance variation in a platform fed-batch production process, Anthony Grippe (Abstract)
Combinatorial Fusion TAG yields powerful platform process for the production of pharmaceutically relevant proteins, Christoph Köppl, Monika Cserjan-Puschmann, Nico Lingg, and Gerald Striedner (Abstract and Presentation)
Developing methods for the production of antiviral VHH-Fc antibodies in Pichia pastoris for fast pandemic response, Chiara Lonigro, Loes Van Schie, Sandrine Vanmarcke, Katrien Claes, Simon Devos, Wannes Weyts, Wim Nerinckx, Bert Schepens, Xavier Saelens, and Nico Callewaert (Article)
Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris, Jennifer Staudacher, Corinna Rebnegger, Diethard Mattanovich, and Brigitte Gasser (Abstract)
Accurate scaleable microfermentation screening for microbial cell line development of therapeutic proteins, Erik Nordwald, Robert Todd, Tyler Telander, Aaron Pilling, and Julius Johnson (Abstract)
Optimization of E. coli SoluPro ® using synthetic biology to generate high-performance microbes for scalable production of protein therapeutics, Drew Tack (Abstract)
Growth-decoupled recombinant protein production in Escherichia coli, Patrick Stargardt, Lukas Feuchtenhofer, Jürgen Mairhofer, Florian Weiss, and Gerald Striedner (Abstract)
Development of the filamentous fungus Myceliophthora thermophila C1 into a next-generation therapeutic protein production system, Andriy Kovalchuk (Abstract)
Robust protein production and secretion in bacteria using type III secretion system, Danielle Tullman-Ereck (Abstract)
Robust, reliable and controlled bio-methane production, Behnam Taidi (Abstract and Presentation)
Controlling the size and linkage type of biopolymers derived from sucrose, Magali Remaud-Siméon (Abstract)
Biosensors and biocatalysis for biorefinery and bioremediation, Neil Dixon (Abstract)
A biotechnological strategy for the valorization of cellulose through Levoglucosenone, Louis Mouterde, Florent Allais, and Jon D. Stewart (Abstract)
Unraveling acetogen gas fermentation using quantitative systems biology, Kaspar Valgepea, Renato d.S.P. Lemgruber, Vishnuvardhan Mahamkali, Kieran Meaghan, Gert Talbo, Robin W. Palfreyman, Ricardo Axayacatl Gonzalez Garcia, Nobuaki Takemori, Ayako Takamori, Christopher de Bakker, Christina Ludwig, Tanus Abdalla, Björn Heijstra, James B. Behrendorff, Alexander P. Mueller, Ryan Tappel, Séan D. Simpson, Michael Köpke, Lars K. Nielsen, and Esteban Marcellin (Abstract)
Developing a novel microbial host and synthetic biology tools for valorizing waste polyethylene terephthalate and lignin-derived compounds, Tae Seok Moon, Jinjin Diao, and Yifeng Hu (Abstract)
Fungal highways enable migration and communication of engineered bacteria in soil, Eric Young, Nilesh Sharma, Felipe Carrillo, Jaclyn Thompson, Allison Taggart, Jacob Beal, Miles Rogers, and Natalie Farny (Abstract)
Treating microbial systems engineering as an inverse function problem to enhance production of biomolecules, Ranjan Srivastava (Abstract)
Metabolic modeling for the microbiome, Costas Maranas, Debolina Sarkar, and Joshua Chan (Abstract)
Engineering microbes and biology for communicating with electronics, William Bentley and Robert E. Fischell (Abstract)
Novel technologies are key for the development of live bacterial therapeutics, Christophe Lacroix (Abstract)
Metabolic Engineering, Kristala L. J. Prather (Abstract)
New kid on the block: Industrialization of cell-free synthesis for biotherapeutics development, Marcella Yu (Abstract)
Rapid iterative design of tandem-core virus-like particles using Escherichia Coli-based cell-free protein synthesis, Beatrice Melinek, Jaime Teneb-Lobos, Beatrice Melinek, Stefanie Frank, Alex Ramirez, William Rosenberg, and Daniel G. Bracewell (Abstract and Presentation)
Next wave of microbially expressed Biologics – a step towards synthetic biology, Thomas Sauer (Abstract)
Continuous culture reborn or revived?, Charles Cooney (Abstract)
Reimagining biomanufacturing for equitable access to medicines: The Resilience Story, Rahul Singhvi (Abstract)
Product and host engineering for low-cost manufacturing of therapeutic proteins in yeast, Neil Dalvie (Abstract)
Development of affordable recombinant glycoconjugate vaccines in bacterial cells, Brendan Wren (Abstract)
Late stage process development for a commercial streptococcus pneumoniae fermentation bioprocess, Matthew Woodling, Christopher Lee, and Jon Shanter (Abstract)
Optimising mRNA vaccines manufacturing by using Machine learning approaches, Sara Sousa Rosa, Sara Sousa Rosa, Davide Nunes, Luis Antunes, Duarte MF Prazeres, and Ana M. Azevedo (Abstract)
Challenges in implementing single-use processing for the purification of polysaccharides, Francis DiGennaro, Nick Samuelson, and Emily Wen (Abstract)
Microbial platform for vaccine production for low and medium income countries (LMICs): 2 case studies, Salome De Magalhaes, Almir Yamanie, Neni Nurainy, and Eli Keshavarz-Moore (Abstract)
Bioengineering bacterial protein nanocompartments as modular platforms for vaccines and drug delivery, Stefanie Frank (Abstract)
Engineering Pichia pastoris to make the impossible hamburger possible, Smita Shankar (Abstract)
Yarrowia lipolytica as a chassis for isoprenoid production, Aleksander Kruis, Peter Panjan, Tilen Konte, Gregor Kosec, and Tadej Markuš (Abstract)
Selective in vitro loading of proteins into protein nanocompartments for applications in the bioindustry, Alexander Van de Steen and Stefanie Frank (Abstract)
Impact of oxygen availability on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris, Aliki Kostopoulou, Corinna Rebnegger, Brigitte Gasser, and Diethard Mattanovich (Abstract)
Use of Genome-scale Models to get new insights into the MarineActinomycete genus Salinispora: Microbial engineering and its application in secondary metabolite production, Barbara A. Andrews, Carolina A. Contador, and Juan A. Asenjo (Abstract)
Hidden methanol assimilation pathways in the methylotrophic yeast Pichia pastoris, Bernd Mitic, Christina Troyer, Stephan Hann, Diethard Mattanovich, and Tim Causon (Abstract)
Caprylate production with lactate as electron donor using Megasphaera hexanoica, Byoung In Sang, Seongcheol Kang, Hyunjin Kim, Byoung Seung Jeon, and Okkyoung Choi (Abstract)
Semi-rational engineering of Adh2 for improved methanol utilization in Komagataella phaffii, Charles Moritz, Enikö Hermann, Clemens Peterbauer, and Diethard Mattanovich (Abstract)
Baker's yeast breeding and engineering to improve biologics manufacturing, Chris Finnis, Les Evans, Ed Louis, and Anne Henstra (Abstract and Presentation)
Rapid iterative design of tandem-core virus-like particles using Escherichia coli- based cell-free protein synthesis, Daniel G. Bracewell, Jaime Teneb-Lobos, Stefanie Frank, Daniel G. Bracewell, Beatrice Melinek, Alex Ramirez, and William Rosenberg (Abstract)
A chalcone synthase-like bacterial protein catalyzes heterocyclic c-ring cleavage of naringenin to alter bioactivity against nuclear receptors in colonic epithelial cells, Ebru Ece Gulsan, Farrhin Nowshad, Stephen Safe, Meredith Leigh Davis, Jimmy Walter Crott, Arul Jayaraman, and Kyongbum Lee (Abstract)
Accurate, scalable microfermentation screening for microbial cell line development of therapeutic proteins, Erik Nordwald, Robert Todd, Tyler Telander, Aaron Pilling, and Julius Johnson (Abstract)
Increasing the carbon efficiency of citric acid production, Evelyn Carolina Vásquez Castro, Özge Ata, Michael Sauer, Matthias G.. Steiger, and Diethard Mattanovich (Abstract)
Towards a platform process for the manufacture of glycoconjugate vaccines for pneumococcal disease, Frank Baganz, Neha Patel, Emily Kay, Jon Cuccui, Tarit Mukhopadhyay, and Michael Sulu (Abstract and Presentation)
Pathway design for mixotrophic production of biochemicals from CO2 and methanol in yeasts, Golnaz Memari, Özge Ata, and Diethard Mattanovich (Abstract)
Method development, validation, and implementation of Raman spectroscopy as an in-situ process analytical technology for fermentation process development and commercial manufacturing, Griffin Thomas, James O’Connor, Brian Marks, Matthew Woodling, and Jon Shanter (Abstract)
Genetically encoded biosensors as tools for the up-cycling of aromatic-based feedstocks, Guadalupe Alvarez Gonzalez and Neil Dixon (Abstract)
Unfolded protein response biosensors for recombinant protein expression, Helena Godon, Sonakshi De, Núria Adelantado, Christoph Kiziak, Brigitte Gasser, and Diethard Mattanovich (Abstract)
High-throughput enzyme engineering for commercial-scale production of natural products, Irina Koryakina, Yue Yang, Svetlana Borisova, William Draper, Wenzong Li, and Victoria Hsiao (Abstract)
mDOE for development of optimized fed-batch cultivation for the production of PET degrading enzymes in E. coli, Lisa Fohler (Abstract)
Lactic acid production in the synthetic autotroph Komagataella phaffii, Michael Baumschabl, Thomas Gaßler, Özge Ata, and Diethard Mattanovich (Abstract)
Clickable Shiga Toxin tracer for drug delivery, Natalia Karolina Danielewicz (Abstract)
From flask to large scale high cell density production of ω-transaminase using auto- induction media, Sofia Nunes, Mario A. Torres-Acosta, Sarah Slack, and Andrea Rayat (Abstract)
Genetically stable CRISPR-based kill switches for engineered microbes, Tae Seok Moon, Austin G. Rottinghaus, Aura Ferreiro, Skye R.S. Fishbein, and Gautam Dantas (Abstract)
Investigating the role of oxidative stress response genes in protein secretion using a novel combinatorial Golden Gate based approach, Victor Mendes Honorato, Jennifer Staudacher, and Brigitte Gasser (Abstract)
Novel Cold-Adapted Lipase from Marine Plankton, Salpa thompsoni, Brenda Parker, Alexander Cotton, Dr Iwan Roberts, Professor John Ward, Dr Will Goodall-Copestake, and Dr Brenda Parker (Abstract)
Optimisation of an alkaline lysis process for a plug- and play plasmid DNA production, Fatma Mohamed Ebrahim Alhamer Almulla and Eli Keshavarz-Moore (Abstract)