ECI Digital Archives

Title

Sustained release vaccine platforms for enhanced humoral immunity

Authors

Gillie Agmon, Stanford University, USA
Emily Gale, Stanford University, USA
Caitlin Maikawa, Stanford University, USA
Anthony Yu, Stanford University, USA
Eric Appel, Stanford University, USA

Conference Dates

June 5-9, 2018

Abstract

Vaccines aim to modulate the immune system to elicit a sufficiently robust, yet targeted, immune response with specifiable immune cell phenotypes.^1,2 Failure of a single vaccine administration to elicit such a response likely arises from inappropriate temporal control over antigen/adjuvant presentation and immune cell activation.² Recent work demonstrates the potential for sustained, low-level presentation of antigens and adjuvants for just over a week to yield more potent and long-lasting immunity.³

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Recommended Citation

Gillie Agmon, Emily Gale, Caitlin Maikawa, Anthony Yu, and Eric Appel, "Sustained release vaccine platforms for enhanced humoral immunity" in "Nanotechnology in Medicine II: Bridging Translational in vitro and in vivo Interfaces", Millicent Sullivan, PhD, University of Delaware, USA Josué Sznitman, Dr. Sc., Technion-Israel Institute of Technology, Israel Lola Eniola-Adefeso, PhD, University of Michigan, USA Srivatsan Kidambi, PhD, University of Nebraska - Lincoln, USA Eds, ECI Symposium Series, (2018). https://dc.engconfintl.org/nanotech_med_ii/1