Invited - Droplets driving and sensing pixel circuits for thin film transistor-based digital microfluidics

Conference Dates

May 15-18, 2023


Thin film transistor-based active-matrix digital microfluidics (AM-DMF) is an emerging and promising technology for large-scale parallel biological sample handling. With electrowetting-on-dielectric (EWOD) method, DMF chip can realize accurately controlling discrete droplets, thus it has great application prospects in biology, chemistry, and drug discovery. With the rapid development of micro-analysis and detection requirements, the precise control of droplets in DMF chips is increasingly required, so it is necessary to conduct the real-time sensing of droplet position.

Figure 1 shows the designed droplet position detection unit circuit. The circuit consists of six thin film transistors, T1-T6. The input signals mainly include the enable signal Ven, the reverse enable signal Venb, the discharge signal Vdischarge, the detection signal Vdetect, and the ground signal Vgnd. The signal Vdrive is the driving voltage applied for driving electrode. Cpixel is the equivalent capacitance between the two plates of a pixel electrode in a microfluidic chip. Vout is the output voltage signal.

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