May 19 - 24, 2024
Los Cabos, Mexico
| Chairs: | Linda Lua, The University of Queensland, Australia |
|---|---|
| Charles Lutsch, Sanofi-Vaccines, France | |
| Francesc Gòdia, Universitat Autònoma de Barcelona (UAB), Spain | |
| Tara Tagmyer, CMC Leader, USA |
24 conference program - Vaccine Technology IX, Linda Lua, Charles Lutsch, Francesc Gòdia, and Tara Tagmyer (Article)
The need for manufacturability speed, Michael Anyadiegwu (Abstract and Presentation)
A next generation of COVID-19 vaccine based on the Newcastle disease virus (NDV) vector, Weina Sun (Abstract)
A comprehensive post-COVID-19 Look at different vaccine platforms: Characteristics, performance, and economic considerations, Florian Krammer and Tania Chilima (Abstract)
C1 gene expression platform: Rapid, high yield and lower cost way to develop and manufacture biologics, Mark Emalfarb, Ronen Tchelet, Noelia Valbuena, and Joseph Hazelton (Abstract)
Development of a nanoparticle-based nasal vaccine against SARS-CoV-2, Jorge Kalil, Roberta Liberato Pagni, Ana Iochabel Soares Moretti, Keity Souza Santos, Edécio Cunha-Neto, Verônica Porto Carreiro de Vasconcellos Coelho, Marco Antônio Stephano, Marcos Camargo Knirsch, Koiti Araki, Silvia Beatriz Boscardin, Daniela Santoro Rosa, and Ana Maria Moro (Abstract and Presentation)
Rapid screening and scaled manufacture of immunogenic virus-like particles in a tobacco BY-2 cell-free protein synthesis system, Jorge Armero-Gimenez, Ruud Wilbers, Arjen Schots, Charles Williams, and Ricarda Finnern (Abstract)
Past, present, and future of vaccine technologies, David Kaslow (Abstract)
Applying intensification and process integration to accelerate development and scale-up of vaccine production, Mathias Garny (Abstract and Presentation)
Continuous production of influenza VLPs using IC-BEVS: A multi-stage bioreactor approach, Ricardo Correia, Taja Zotler, Miguel Graça, Bárbara Fernandes, Gorben Pijlman, Paula M Alves, and António Roldão (Abstract)
Intensification of Adenovirus manufacturing by developing a high cell density perfusion process, Alena Roßkamp, Carina C. D. Joe, Alexander D. Douglas, and Julia Niemann (Abstract)
Accelerating recombinant protein vaccine development and manufacturing preparation of Disease X, Tshering Sherpa and Jian He (Jason) (Abstract)
Optimization and scale up of suspension Vero cell culture technology towards industrial applications in cost-effective production of viral vaccines and therapeutic viruses, Chun Fang Shen, Elodie Burney, Rénald Gilbert, Amine Kamen, and Martin Loignon (Abstract)
Empowering vaccine efficacy and distribution: Harnessing Machine Learning for Structural Optimization and Advanced Formulations to Enhance Accessibility, Jason Zhang (Abstract)
Tackling mRNA Vaccine Manufacturing Optimization From vaccine production to its purification, Salome De Sa Magalhaes, Shuran Zhang, Duarte MF Prazeres, Ana M. Azevedo, and Marco PC Marques (Abstract)
Genetic engineering of influenza A virus defective interfering particles towards improved antiviral efficacy and potential use as a live vaccine, anya Dogra, Lars Pelz, Daniel Ruediger, Julia Boehme, Maike Baelkner, Olivia Kershaw, Yvonne Genzel, Dunja Bruder, Sascha Kupke, and Udo Reichl (Abstract)
Integrated platform for the rapid development of Thermostable VLP and CircRNA VLP vaccines, Prabuddha Kundu (Abstract)
The role of vaccines in controlling emerging diseases, Abby Patterson (Abstract and Presentation)
Enhancing purification of Adenovirus-like particles (Addomer) for snakebite therapy, Antonio Roldao, Cláudia Paiva, Emerson Dilla, Justin Sargunas, Mafalda Moleirinho, Paula Alves, António Roldão, and Cristina Peixoto (Abstract)
Process optimization for recombinant Marburg Virus Glycoprotein production using Drosophila S2 Cells, Sven Goebel, Earl Pineda, Michael Keebler, Tibor Anderlei, Yvonne Genzel, Udo Reichl, and Axel T. Lehrer (Abstract)
T-cell immunogenicity of an MVA-based vaccine candidate against Middle East Respiratory Syndrome in humans, Leonie Mayer, Marylyn M Addo, Caroline E. Harrer, Christine Dahlke, Svenja Hardtke, Maren Sandkuhl, My Linh Ly, Monika Rottstegge, Matthijs P. Raadsen, Christine Dahlke, Anahita Fathi, Bart L. Haagmans, Eric CM van Gorp, Gerd Sutter, and Stephan Becker (Abstract)
Development of a vaccine candidate against dengue and Zika viruses by presenting a mimotope on the capsid of adeno-associated virus serotype 8, Arturo Liñan, Esmeralda Cuevas-Juárez, Octavio T. Ramírez, Ana Ruth Pastor, Roberto C. García, and Laura A. Palomares (Abstract)
Analytical characterization in an era of precision vaccinology, Julia O’Neill (Abstract and Presentation)
Cytokine secretion as fast in-process control for live virus potency, Johanna Bacher and Alois Jungbauer (Abstract)
More adenovirus, more quickly and better quality, Shawkat Hussain, Jacqueline Vieira, Marco Polo Peralta-Alvarez, Julia Talarek, Carina C D Joe, and Alexander D Douglas (Abstract)
A rationale design of a pneumococcal multi-epitope vaccine: from immunobioinformatics to bench-scal, Victor Alves; Eneas Carvalho; Vinicius Souza; José Patané; and Viviane, Gonçalves (Abstract)
Strengthening product viral safety while streamlining the testing package: Sanofi vaccine development and implementation of high-throughput sequencing for adventitious virus detection, Carine Logvinoff (Abstract and Presentation)
Animal, Human and Environmental Health, they are all connected, Albert Osterhaus (Abstract)
Improving vaccine efficacy through rational formulation design, Dennis Christensen (Abstract)
Tee mixing as an alternative method to form stable emulsion-based adjuvants, Marissa Bradley, Randy Soukup, and Marissa Bradley (Abstract)
Formulation optimization focused on safety and thermostability of a single-vial bivalent Sudan Ebola virus and Marburgh Virus Vaccine, Axel Lehrer, Teri Ann S. Wong, Michael M. Lieberman, Oreola Donini, Thomas Geisbert, and Albert To (Abstract)
Multivalent MVA-vectored vaccine elicits EBV neutralizing antibodies in rhesus macaques that reduce EBV infection in humanized mice, Ivana Reidel, Gabriela M. . Escalante, Simeon Cua, Brenda Alvarado, Esther Rodriguez, Cloe Zimmerman, Murali Muniraju, Lorraine Z. Mutsvunguma, He . Li, Aparna N. Govindan, Michael K. . Axthelm, Scott W. Wong, and Javier Gordon Ogembo (Abstract)
Development of a broadly protective neuraminidase-based Influenza Virus vaccine, Irene Hoxie, Kirill Vasilev, Madhumathi Loganathan, Benjamin Francis, Jordan Clark, Jay Evans, David Burkhart, and Florian Krammer (Abstract)
Accelerating access to sustainable vaccine adjuvant technology, Chris Fox (Abstract and Presentation)
The regional manufacturing of and open access to poly ICLC (Hiltonol®) for human and veterinary vaccines, Andrew Simpson, Otavia Caballero, Julia Castro, Ricardo Gazzinelli, and Andres Salazar (Abstract)
A new academia-industry partnership enabling sustainable and responsive vaccine manufacture, Martina Micheletti (Abstract)
Avian Influenza H5n1 and H7n3 vaccine candidates, from design to evaluation, Leandro Alberto Nuñez Muñoz, Berenice Calderón-Pérez, Víctor Ortiz-Juanillo, Pedro Ricardo Rodríguez-Farrera, Roberto Ruiz-Medrano, and Beatriz Xoconostle-Cázares (Abstract)
Anti Covid-19 Soberana vaccines: Two immunogens, one process, Tammy Boggiano, Julio Palacios, Lourdes Hernandez, Gertrudis Rojas, Annia Cabrales, Eduardo Ojito, and Sum Lai Lozada (Abstract)
Advances in alternative routes of vaccine administration, and continued challenges, Tanima Sinha (Abstract and Presentation)
Injectable core-shell particles deliver prime-boost immunization in a single shot, Romain Guyon, Anita Milicic, Sören Reinke, Luca Bau, and Eleanor Stride (Abstract)
Understanding the enhanced immune responses to High-Density Microarray Patch vaccination through spatial transcriptomics and antibody repertoire analysis, David Muller, Christopher L.D. McMillan, Jovin Choo, Danushka Wijesundara, and Paul R. . Young (Abstract)
Microarray patch delivery of unadjuvanted recombinant spike protein vaccine induces potent and broad-spectrum immune responses in a phase I clinical study, Thomas Lake, Alexandra C. I. Depelsenaire, Andrew Robertson, Kelly-Anne Masterman, Cesar Jayashi Flores, David A. Muller, Julian Hickling, Adam Wheatley, Jennifer Juno, Stephanie Wallace, and Angus Forster (Abstract)
Enabling vaccine technologies to save more lives, Katey Owen (Abstract)
Tyrosinase-mediated bioconjugation of antigens to ferritin nanoparticles, Margarida Q. Rodrigues, Sara Patão, Paula M. Alves, António Roldão, and Mónica Thomaz (Abstract)
Multifactorial high-throughput process screening for a yellow fever virus-vectored Zika vaccine candidate, Sven Göbel, Ozeir Kazemi, Ingo Jordan, Kai Dallmeier, Yvonne Genzel, and Udo Reichl (Abstract)
Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice, Eduard Puente-Massaguer, Kirill Vasilev, Benjamin Francis, Madhumathi Loganathan, Guha Asthagiri Arunkumar, Michael J. Scherm, Irene Gonzalez-Dominguez, Annika Beyer, Xueyong Zhu, Lynda Coughlan, Ian A. Wilson, Weina Sun, Florian Krammer, and Peter Palese (Abstract)
A scalable, serum-free cell culture platform for improved production of diverse live virus and viral vector vaccine candidates, James Wagner, Daniel Spatafore, Justin Ma, and Adam Kristopeit (Abstract)
Influenza A defective interfering particles as broad-spectrum antivirals, Sascha Young Kupke, L Pelz, D Ruediger, T Dogra, J Boehme, O Kershaw, D Bruder, and U Reichl (Abstract)
C1 gene expression platform rapid, high yield and lower cost way to develop & manufacture biologics, Mark Emalfarb, Ronen Tchelet, Joseph Hazelton, and Noelia Valbuena (Abstract)
Enabling commercial process oriented clone selection for a pipeline vaccine candidate through process scale down and analytical characterization, Matthew Woodling, Sheng-ching Wang, Zhiguo Liu, Anthony Grippe, and Alyssa Innes (Abstract)
Developing vaccines for common respiratory viruses using a platform technology, Andrew Young and A/Prof Keith Chappell (Abstract)
Enhancing NA immunogenicity through novel VLP designs, Leticia Guzmán-Ruiz, Alexander Zollner, Irene Hoxie, Alois Jungbauer, Miriam Klausberger, Florian Krammer, and Reingard Grabherr (Abstract and Presentation)
Development of a rapid, cost-effective bioprocess for the production of recombinant human serum albumin in Pichia Pastoris, Wanqin Soh (Abstract)
Development of the Thermophilic Filamentous Fungus Thermothelomyces heterothallica C1 into a prominent human and animal vaccines production platform, Mark Emalfarb (Abstract)
Production of AAV virus-like particles in CHO cells for bioorthogonal chemistry applications, Daniel Barreto-Cabrera, Octavio T. Ramírez, and Laura A. Palomares (Abstract)
Rapid screening and scaled manufacture of immunogenic virus-like particles in a tobacco BY-2 cell-free protein synthesis system, Jorge Armero Gimenez, Ruud Wilbers, Arjen Schots, Charles Williams, and Ricarda Finnern (Abstract)
Oral administration of a recombinant RBDw like from SARS-CoV-2, as immunostimulant for the care of COVID-19, Norma Adriana Valdez-Cruz, Mauricio A. Trujillo-Roldán, Enrique García-Hernández, Laura Cobos-Marín, Alejandro Alagón, and Octavio R. Ramírez-Reivich (Abstract)
FinaXpress, an E. Coli platform for the expression of disulfide-bonded proteins - production of low-cost carrier proteins, vaccine antigens, and biotherapeutics, Renaud Jacquemart, Andrew Lees, and Natalia Oganesyan (Abstract)
Pandemic Preparedness with ALiCE® - Scalable eukaryotic cell-free protein synthesis enables ultra-rapid threat response, Charles Williams (Abstract)
Self-amplifying mRNAs encoding chimeric or mosaic influenza virus hemagglutinin antigens induce broadly protective antibody responses in mice, Juan Manuel Carreno Quiroz, Anass Abbad, Justine S.. McPartlan, Dominika Bielak, Poulami Talukder, Keren Greenbaum Schmahmann, Eduard Puente-Massaguer, Temima Yellin, Adolfo García Sastre, Sadaf Asla, Madhumathi Loganathan, Benjamin Francis, Leeba Sullivan, Miriam Fried, Christian W. Mandl, Jasdave S. Chahal, and Florian Krammer (Abstract)
Engineering protein nanocompartments for a novel mRNA loading and delivery system, Ferdinando Sereno, Andrea Rayat, and Stefanie Frank (Abstract)
Efficient supply of high quality lineralised pDNA for mRNA production, Salomé A. de Sá Magalhães and Eli Keshavarz-Moore (Abstract)
Optimizing in-vitro transcription parameters for production of messenger RNA (mRNA) vaccines, Julia Puppin Chaves Fulber,; Maryam Youssef; Cynthia Hitti; and Amine A. Kamen (Abstract)
A Phase I, randomized, double-blind, placebo-controlled trial of a Reprna-based vaccine for Covid-19: A brief analysis of safety in adults, Bruna Machado, Katharine Hodel, Camila Valente, and Milena Soares (Abstract and Presentation)
Development of Rna Vaccines for leishmaniasis and comparison with vaccines based on recombinant antigens, Gabriela de Asis Burle-Caldas, Isabela Vieira da Costa, Renata Salgado Fernandes, Bianca de Oliveira, Ana Flávia Bráz, Diego dos Santos Ferreira, Frederico Crepaldi Nacimento, Ricardo Tostes Gazzinelli, Ana Paula Fernandes, and Santuza Maria Ribeiro Teixeira (Abstract)
Univercells develops breakthrough technologies and services that democratize the production of biologics: The potential of Drug Development collaboration, David Honba and Héla Kallel (Abstract)
Development of a Marburg self-amplifying mRNA-lipid nanoparticle vaccine: Differential effects when co-formulated with Toll Receptor Agonists, Allan Watkinson, Gillian Hoover, Anas Tomeh, Sarah Horst, Erik de Leeuw, and Murty Chengalvala (Abstract and Presentation)
A novel genetic vaccine platform using tag/catcher conjugation for modular assembly and secretion of antigen-displaying capsid virus-like particles, Cyrielle Fougeroux (Abstract)
Process development for high titer production of RCA free adenovirus in suspension complementing cell culture derived from A549 cell line, Chun Fang Shen, Elodie Burney, Martin Loignon, and Rénald Gilbert (Abstract)
Immunogenicity of a trivalent recombinant antigen based on SARS-CoV-2 receptor- binding domain and its variants of concern, Berenice Calderón-Pérez, Leandro Alberto Núñez-Muñoz, Lady Laura Trejo-Ayala, Víctor Hugo Rosales-García, Benjamín Emmanuel Chávez-Álvarez, Roberto Ruiz-Medrano, and Beatriz Xoconostle-Cázares (Abstract and Presentation)
Development of a vaccine candidate against Clostridium botulinum in cattle, Berenice Calderón-Pérez, Leandro Núñez-Muñoz, Beatriz Xoconostle-Cázares, Roberto Ruiz-Medrano, Ana Magdiel Iturbide-Hernández, Yesica Aguilar-Hernández, Víctor Hugo Rosales-García, and Benjamín Emmanuel Chávez-Álvarez (Abstract and Presentation)
Acheviements of a vaccine development unit within Lmics; Biotechnology development unit, Institut Pasteur de Tunis, Tunisia, Samia Rourou, Amani Chaabene, Said Salhi, Samy Majoul, Khaled Trabelsi, Hana Askri, and Hela Kallel (Abstract and Presentation)
Upstream development for a Zika Virus Chimeric vaccine, Tiago Pereira dos Santos, Stephanie Almeida da Silva, Ygara da Silva Mendes, Kelly Araújo Lucio, Rafael Araújo Mendonça, Renata Tourinho Santos Cantinho Brício, Mariana Pierre de Barros Gomes, Laura Helena Vega Gonzales Gil, Helena Keiko Toma, Elena Cristina Caride, and Noemi Rovaris Gardinali (Abstract and Presentation)
Recombinant interleukins as vaccine adjuvants against livestock diseases, Berenice Calderón-Pérez, Leandro Alberto Nuñez-Muñoz, Ana María Cortés-López, Pedro Ricardo Rodríguez-Farrera, Roberto Ruiz-Medrano, Beatriz Xoconostle-Cázares, and Areli Margarita Martínez-Morales (Abstract and Presentation)
Manufacture of a SARS-CoV2 vaccine in Mexico, Néstor O. Pérez, Gabriela Mortera, and Jaime Uribe W (Abstract)
Validation of a serological ELISA method to detect anti-SarsCov2 IgG and IgM antibodies in Mexican population, Mabel Rodriguez, Luis Fernando Losoya, Luis Eduardo Hernandez, Arlene Calderón, Maricela Olvera, Juan Carlos Rivera, Miguel Mendoza, Laura Alicia Palomares, Octavio Tonatiuh Ramírez, and Daniel Barreto (Abstract and Presentation)
Modeling the benefits of small molecule Viral Sensitizers (VSEsTM) to increase virus production, Andrea Vervoort, Jondavid de Jong, Keara Sutherland, and Andrea Vervoort (Abstract)
Disruptive Vibro® technology offering new opportunities in vaccine manufacturing processes, Jarno Robin (Abstract)
Intensification of virus production in suspension cells: Comparison of perfusion and fed batch-based processes for different cell lines, Cristina Silva, Yvonne Genzel, Udo Reichl, Amine A Kamen, and Olivier Henry (Abstract)
The production and purification of an intermediate product for large scale VLP production in insect cells - baculovirus working stock, Lena Achleitner, Patricia Aguilar, Nico Lingg, Peter Satzer, and Alois Jungbauer (Abstract)
Fixed-bed bioreactor production of virus for vaccine manufacturing, Renato Astray, Flavia Ferreira Barbosa, Júlio Cesar Lima Alves Cassoli, Rosana de Lima Paoli, Viviane Botosso, Ana Priscila Perini de Araújo, and Nicole Assis Pereira (Abstract)
Sterile purification of large viruses using functionalized non-woven fibers, Patricia Pereira Aguilar, Lena Achleitner, and Nico Lingg (Abstract)
Influenza A virus production following quality by design principles, Tilia Zinnecker, Kristin Thiele, Udo Reichl, and Yvonne Genzel (Abstract)
Development of next generation manufacturing platform technology for the production of viral vectored vaccines, Lawrence Yap, Wanqin Soh, and Dilshan Amarasekara (Abstract)
Evaluation of a universal influenza B vaccine based on the mosaic hemagglutinin strategy using different vaccine platforms in mice, Irene González-Domínguez, Eduard Puente-Massaguer, Adam Abdeljawad, Tsoi Ying Lai, Yonghong Liu, Madhumathi Loganathan, Hiromi Muramatsu, Jose Martínez-Guevara, Stefan Slamanig, Marta Boza, Victoria Dolange, Nicholas Lemus, Benjamin Francis, Norbert Pardi, Florian Krammer, Peter Palese, and Weina Sun (Abstract)
Bioprocess improvement to increase manufacturing yield using a fixed-bed bioreactor, Pei-Yin Lim, Elvin Woon, Anu Maashaa Nedumaran, and Edward Lim (Abstract and Presentation)
Development of a trivalent adjuvanted sub-unit vaccine candidate for Covid-19: From antigen expression to Ind-enabling Cmc and preclinical studies, Leda R. Castilho, Renata G. F. Alvim, Tulio M. Lima, Luiza Abdo, Karina Hadju, Daniel P. B. Abreu, Patricia R. C . França, Gabriane Porcino, Fernanda Bittencourt, Ana L. Habigzang, Federico F. l Marsili, Hiam Arruda, Guilherme A. Oliveira, Renato S. Carvalho, and Martin H. Bonamino (Abstract)
Purification platform for poxviruses by filtration processes, Michael y Wolff, Linus G. Weber, Philis M. Peedieckal, Leon Freitag, Keven Lothert, and Mariana S. Fonseca (Abstract)
The development of a Hi5-Cas9 stable cell line for assessing the impact of AcMNPV essential gene disruption on baculovirus & recombinant protein production using CRISPR-Cas9 technology, Jacqueline Powichrowski, Madhuja Chakraborty, and Lisa Nielsen (Abstract and Presentation)
Impact of animal origin free peptones on HEK293 and vero based vaccine applications, Ashwin Gurunathan, Wen-Yang Tsai, Matt Rosecrans, Aaron Robinson, Bilal Mughal, Anna-Barbara Hachmann, Stacy Holdread, James W. Brooks, and Syed Muaz Khalil (Abstract)
Influenza virus capture using membrane chromatography: Improving selectivity by matrix design and pseudo-affinity ligand interactions, David Dauer, Ana-Raquel Fortuna, Florian Taft, André Krause, Michael Wolff, Udo Reichl, and Volkmar Thom (Abstract)
Rapid multiplexed analytics for mRNA vaccines, Erica Dawson (Abstract)
Extraction of intact proteins from polyacrylamide gels for virus-like particle purity reversed-phase HPLC method development, Jonathan Welsford, James Deng, Paul Gillespie, Malini Mukherjee, George Perkins, and Dustin Klein (Abstract)
Asymmetric flow field flow fractionation as an analytical tool for virus-like particles, Narges Lali, Johanna Bacher, Tomas Mesurado, Alois Jungbauer, and Patricia Pereira Aguilar (Abstract)
Quality assessment of virus-like particle: A new transmission electron microscopy approach, Salomé A. de Sá Magalhães, Emiliana De Santis, Saba Hussein-Gore, Mathieu Colomb-Delsuc, and Eli Keshavarz-Moore (Abstract)
Application of multivariate data analysis on multi-sensor system for in-line process monitoring of adenovirus production in HEK293 cells, Xingge Xu, Omar Villar, Barbara Paes, Sean Nesdoly, and Amine A. Kamen (Abstract and Presentation)
Redox potential of intercapsomeric disulfides defines pathway of final VLP assembly for HPV, Danielle Miller, Arthur Dechamps, Oleksandr Zavalov, Benjamin Roose, Feras Hatahet, Mark Haverick, and Emily Wen (Abstract)
Opportunities for process analytical technology integration in the QbD framework for vaccine formulation development and manufacturing, Nausheen Rahman, Kirsten Strahlendorf, and Chrisford Ling (Abstract)
Addressing vaccine stability and cold chain challenges with recombinant human serum albumin to enable global administration, Mark Stathos; Cameron Martin PhD; Pratik Katwal PhD; and Elliott Renft, Director (Abstract)
Bioprocess studies for the production of bacterial vesicles for the delivery of immunogens in epithelial cells, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz, Laura M. Muñoz-Echeverri, and Santiago Benavides-López (Abstract)