June 17-22, 2018
Fairmont Tremblant
Mont Tremblant, Quebec, Canada
| Editors: | Amine Kamen, McGill University |
|---|---|
| Tarit Mukhopadhyay, University College London | |
| Nathalie Garcon, Bioaster | |
| Charles Lutsch, Sanofi Pasteur |
The articles for these proceedings are not peer-reviewed.
Orbital shaken bioreactor for influenza A virus production in high cell density cultivations, Juliana Coronel, Yvonne Genzel, Udo Reichl, Ilona Behrendt, Tim Bürgin, Tibor Anderlei, and Volker Sandig (Abstract)
Vaxarray for hemagglutinin and neuraminidase potency testing of influenza vaccines, Kathy Rowlen (Abstract)
Vaxarray potency assay for rapid assessment of “pandemic” flu vaccines, Kathy Rowlen (Abstract)
Application of analytical characterization tools in process and formulation development of low cost vaccines using the ULTRA manufacturing platform, Kawaljit Kaur, John M. Hickey, Nishant Sawant, David A. Holland, Sangeeta B. Joshi, and David B. Volkin (Abstract)
Comparaison of rabies virus purification using different methods, Khaled Trabelsi, Meriem Ben Zakour, and Héla Kallel (Abstract)
Comparative transcriptome analysis of a Trichoplusia ni cell line reveals distinct host responses to intracellular and secreted protein products expressed by recombinant baculoviruses, Krisztina Koczka, Wolfgang Ernst, Reingard Grabherr, Philipp Peters, Heinz Himmelbauer, and Lisa Nika (Abstract)
Generation and efficacy assessment of a chimeric antigen E2-CD154 as a marker Classical Swine Fever Virus subunit vaccine produced in HEK 293 and CHO K1 mammalian cells, Lidice Méndez-Pérez, Elsa M. Rodríguez, Elianet Lorenzo, Alina Rodríguez-Mallón, Alina Venereo, Yanet Prieto, María P. Rodríguez, Marisela Suárez, Yusmel Sordo, Marisdania Joglar, Elaine Santana, Ernesto M. González, Reynier Baez Gomez, Ileanet Avalos, Paula Naranjo, and Mario Pablo Estrada (Abstract)
Production and characterization of HER2-displaying budded virus-like particles and their potential as cancer vaccines, Lisa Nika, Reingard Grabherr, Guha Asthagiri Arunkumar, Florian Krammer, and Sara Cuadrado (Abstract)
Rapid fermentation optimization for vaccine development, Lourdes Velez, Tarit Mukhopadhyay, Stephen A Morris, John Hickey, and Kawaljit Kaur (Abstract)
CRISPR-dCAS9 for controlling baculovirus replication and increasing production of virus-like particles, Mark Bruder and Marc Aucoin (Abstract)
Purification of flavivirus VLPs by a two-step chromatographic process, Matheus Souza and Leda R. Castilho (Abstract)
ExpiSf™: A chemically-defined baculovirus-based expression system for enhanced Protein production in Sf9 cells, Maya Yovcheva, Sara Barnes, Kenneth Thompson, Melissa Cross, Katy Irvin, Natasha Lucki, Henry Chiou, and Jonathan Zmuda (Abstract)
Media formulation to support the growth of Vero cells in suspension, Megan Logan and Marc Aucoin (Abstract)
Accelerating the manufacture of glycoconjugate vaccines for pneumococcal disease, Neha Patel, Tarit Mukhopadhyay, Michael Sulu, Emily Kay, and Jon Cuccui (Abstract)
Development of a vaccine production platform for poultry diseases in Africa: Newcastle Disease Virus non-replicative adenovirus-vectored vaccine, Omar Farnos, Amine Kamen, Héla Kallel, Khaled Trabelsi, Martha Yami, and Esayas Gelaye (Abstract and Presentation)
Formulation and stabilization of a recombinant human Cytomegalovirus vector for use as a candidate vaccine for HIV-1, Ozan S. Kumru, Soraia Saleh-Birdjandi, Lorena Napolitano, Sangeeta B. Joshi, David B. Volkin, Eddy Sayeed, David Robinson, Sjoerd van den Worm, and Klaus Frueh (Abstract)
Formulation development of a stable, orally delivered live human neonatal rotavirus(rv3-bb) vaccine candidate, Prashant Kumar, Swathi Pullagurla, Ravi S. Shukla, Ashaben Patel, Christopher Bird, Ozan Kumru, Sangeeta B. Joshi, and David B. Volkin (Abstract)
Case study: Single-use platform for complete process development and scale-up of an Adenovirus, Rachel Legmann (Abstract)
Development and characterization of a murine hepatoma model expressing hepatitis Cvirus (HCV) non-structural antigens for evaluating HCV vaccines, Kamran Haq, Susanne MacLean, Renu Dudani, Mehdy Elahi, Rénald Gilbert, Risini D. Weeratna, Kevin G. Young, and Lakshmi Krishnan (Abstract)
Case studies: Raman implementation for process lifecycle management in fermentation based processes, Roberto Ortiz, Christine Belzyt, Joseph Threlfall, Jennifer Potter, and Jorge Vazquez (Abstract)
Adaptation of Vero cells to suspension culture and rabies virus production on different SERUM free media, Samia Rourou, Meriem Ben Zakkour, and Héla Kallel (Abstract)
Virus-like particles: A flexible platform for universal influenza vaccine development, Sarah Slack, Tarit Mukhopadhyay, Jonathan Welsh, and Lucy Foley (Abstract)
Characteristics of rVSV-ZEBOV production kinetics in HEK293 and Vero cells, Sascha Kiesslich, Amine Kamen, Jean-François Gélinas, and Rénald Gilbert (Abstract and Presentation)
Laser force cytology for rapid quantification of viral infectivity, Sean J. Hart, Margaret E. McCoy, Zachary L. Evans, Keya L. Rodrigues, and Colin G. Hebert (Abstract)
Fully automated high-throughput process development for the novel purification of rotavirus vaccines, Shaleem I. Jacob, Lourdes Velez, Tarit K. Mukhopadhyay, and Stephen A. Morris (Abstract)
Affinity resin screening for optimal DSP – application to rotavirus vaccine production., Stephen A. Morris, Shaleem Jacob, Lourdes Velez, and Tarit Mukhopadhyay (Abstract)
Rapid virus titration using flow cytometry, Steve George, Patrick Farrell, Megan Logan, and Marc Aucoin (Abstract)
Highly efficient influenza virus production: A MDCK-based high-cell-density process, Thomas Bissinger, Udo Reichl, Yvonne Genzel, Yixiao Wu, Xuping Liu, and Wen-Song Tan (Abstract)
A clinically validated Drosophila S2 based vaccine platform for production of malaria vaccines, Thomas Jørgensen, Max Soegaard, Willem A. de Jongh, Ali Salanti, Morten Nielsen, Kathryn A. Hjerrild, Sumi Biswas, Jing Jin, Simon Draper, and Rebecca Dabbs (Abstract)
Technology transfer for local vaccine production in Argentina, Valeria Brizzio (Abstract)
Real-time stability of a hepatitis E vaccine (Hecolin®) demonstrated with potency assays and multifaceted physicochemical methods, Xiao Zhang, Xin Wang, Yufang Li, Mujin Fang, Jun Zhang, Shaowei Li, Ningshao Xia, Qinjian Zhao, Min Li, Minxi Wei, Zhijie Lin, Zhongyi Li, and Guang Sun (Abstract)
Evaluating the effect of formulation on the uptake of a ZIKA subunit vaccine candidate by antigen-presenting cells, Xiaoling Li, Allan Watkinson, Jakub Dragun, and Peter Laing (Abstract)
Implications of MDCK cell heterogeneity in cell-based influenza vaccine production, Xuping Liu, Liang Zhao, Honglin Wang, Guicai Song, Wen-Song Tan, and Qian Ye (Abstract)
An outbreed mouse model of yellow fever for study of pathogenesis and development of vaccines and therapeutics, Yakhya Dieye, Moussa Dia, André Bedekelabou, and Ousmane Faye (Abstract and Presentation)
Development of stabilizing formulations of a trivalent inactivated poliovirus vaccine in a dried state for delivery in the Nanopatch™ microprojection array, Ying Wan, John M. Hickey, Christopher Bird, Sangeeta B. Joshi, David B. Volkin, Katey Witham, Angus Forster, and Paul Fahey (Abstract)
Efficient influenza vaccine manufacturing: Single MDCK suspension cells in chemically defined medium, Yixiao Wu, Xuping Liu, Wen-Song Tan, Thomas Bissinger, Yvonne Genzel, and Udo Reichl (Abstract)
Analytical characterization and formulation assessment of model secretory- immunoglobulin-A (sIgAs) for their potential use as low cost, orally delivered sIgAs, Yue (Martin) Hu, Ozan Kumru, Jian Xiong, Lorena Napolitano, John Hickey, David B. Volkin, Sangeeta B. Joshi, Yang Wang, Mark Klempner, and Lisa Cavacini (Abstract)
Steric exclusion chromatography for the purification of recombinant baculovirus, Daniel Loewe, Felix B eyer, Gundula Sprick, Peter Czermak, and Michael Wolff (Abstract)
Production and purification of Zika virus for an inactivated virus vaccine candidate, Renato Mancini Astray, Daniella Cristina Ventini-Monteiro, Sandra Fernanda Suárez-Patiño, Ana Priscila Perini de Araújo, Paulo Lee Ho, Ana Marisa Chudzinski-Tavassi, Rosana de Lima Paoli, Soraia Attie Calil Jorge, and Viviane Fongaro Botosso (Abstract)
Co-formulation of broadly neutralizing antibodies 3BNC117 and PGT121:Analytical challenges during pre-formulation characterization and storage stability studies, Ashaben Patel, Vineet Gupta, John M. Hickey, Nancy S. Nightlinger, Richard S. Rogers, Christine Siska, Sangeeta B. Joshi, Bruce A. Kerwin, and David B. Volkin (Abstract)