Defining and characterizing stem cell-derived endocrine cell therapy products: Protocol optimization, Raman spectroscopy biomarkers, and analytical strategy for product identity and potency

Authors

• Diepiriye Iworima, University of British Columbia, CanadaFollow
• Robert Baker, Life Sciences Institute, The University of British Columbia, Vancouver, BC
• Cara Ellis, Life Sciences Institute, The University of British Columbia, Vancouver, BC
• Martha Vardaki, Michael Smith Laboratories, The University of British Columbia, Vancouver, BC
• Shreyas Rangan, Michael Smith Laboratories, The University of British Columbia, Vancouver, BC
• H. Georg Schulze, Michael Smith Laboratories, The University of British Columbia, Vancouver, BC
• Michael Blades, Department of Chemistry, The University of British Columbia, Vancouver, BC
• Robin F.B. Turner, Michael Smith Laboratories; Department of Electrical and Computer Engineering; Department of Chemistry, The University of British Columbia, Vancouver, BC, Canada
• James M. Piret, School of Biomedical Engineering; Michael Smith Laboratories; Department of Chemical and Biological Engineering, The University of British Columbia, Vancouver, BC
• Timothy J. Kieffer, School of Biomedical Engineering; Department of Cellular and Physiological Sciences, Life Sciences Institute; Department of Surgery, The University of British Columbia, Vancouver, BC

Conference Dates

February 1 – 5, 2026

Abstract

Please click Additional Files below to see the full abstract

Recommended Citation

Diepiriye Iworima, Robert Baker, Cara Ellis, Martha Vardaki, Shreyas Rangan, H. Georg Schulze, Michael Blades, Robin F.B. Turner, James M. Piret, and Timothy J. Kieffer, "Defining and characterizing stem cell-derived endocrine cell therapy products: Protocol optimization, Raman spectroscopy biomarkers, and analytical strategy for product identity and potency" in "Advancing Manufacture of Cell and Gene Therapies IX", John Moscariello, Neuvogen, USA Corinne Hoesli, McGill University, Canada Bruno Marques, Century Therapeutics, USA Eds, ECI Symposium Series, (2026). https://dc.engconfintl.org/cell_gene_therapies_ix/21