DNA impurity reduction by a stably integrated staphylococcal nuclease is compatible with high-titer suspension serum-free rAAV manufacturing

Authors

Geoffrey Howe, University College London, United KingdomFollow
Mehtap Bal, University College London
Matt Wasmuth, University College London
Giulia Massaro, University College London
Ahad A. Rahim, University College London
Sadfer Ali, University College London
Milena Rivera, University College London
Desmond M. Schofield, University College London
Aminat Omotosho, University College London
John Ward, University College London
Eli Keshavarz-Moore, University College London
Darren N. Nesbeth, University College London

Conference Dates

February 4 - 8, 2024

Abstract

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Recommended Citation

Geoffrey Howe, Mehtap Bal, Matt Wasmuth, Giulia Massaro, Ahad A. Rahim, Sadfer Ali, Milena Rivera, Desmond M. Schofield, Aminat Omotosho, John Ward, Eli Keshavarz-Moore, and Darren N. Nesbeth, "DNA impurity reduction by a stably integrated staphylococcal nuclease is compatible with high-titer suspension serum-free rAAV manufacturing" in "Advancing Manufacture of Cell and Gene Therapies VIII", Fernanda Masri, Cytomos, United Kingdom; Carolyn Yeago, CY Solutions LLC, USA; Gargi Maheshwari, BMS, USA; John Moscariello, BMS, USA Eds, ECI Symposium Series, (2024). https://dc.engconfintl.org/cell_gene_therapies_viii/23