May 8-13, 2016 - NH La Quinta (Palm Springs area), California, USA

Editors:   Robert Kiss, Genentech
  Sarah Harcum, Clemson University
  Jeff Chalmers, Ohio State University

The articles for these proceedings are not peer-reviewed

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Integration of bioprocess design with transcriptomic and metabolomic characterization for the expansion of human pluripotent stem cells, Marta Silva (Abstract)

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Scalable production of mesenchymal stem/stromal cells from different human sources in microcarrier-based stirred culture systems, Ana Fernandez (Abstract)

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Development of an adherent cell based virus production process in Mobius® sIngleuse bioreactor, Michael Cunningham (Abstract)

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Scaling microcarrier-based cell expansion processes, Mark Szczypka (Abstract)

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Transient production of VLPs in HEK 293 cells and the evaluation of parameters influencing transfection and expression, Daniel Blackstock (Abstract)

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Production of stable, immunogenic foot-and-mouth disease vaccine in a chemicallydefined, serum-free medium optimized for BHK-21 Cells, Paul Gulde (Abstract)

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Development of chemically-defined, animal component-free medium for suspension MDCK cell-based influenza vaccine production, Jenny Bang (Abstract)

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Fluorescent influenza-like particles and control over their composition, Marc Aucoin (Abstract)

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HEK293 suspension cell culture platform for production of viruses and viral vectors, Chun Shen and Sven Ansorge (Abstract)

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Efficient production of influenza virus-like particles in HEK-293SF cells, Alina Venereo (Abstract)

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A flow cytometric granularity assay for the quantification of infectious virus, Megan Logan (Abstract)

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Impact of Poloxamer 188 variability on biologics manufacturing: Mitigations and causal investigation, Salim Charaniya (Abstract)

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Evaluating sugar-based detergents as a potential alternative to poloxamer bubble protectant, Jessica Wuu, Jayanthi Lakkyreddy, and Steven Meier (Abstract)

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A host cell protein that may impact polysorbate degradataion, Kelvin Lee (Abstract)

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Troubleshooting the recover of mater cell bank for a commerical product, Mei Shao and Kishan Rao (Abstract)

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Adapting an in-licensed/acquired cell culture process to platform conditions, Raghunath Shivappa (Abstract)

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Challenges in the development and adaptation of platform process to existing pipeline, Edmund Scarfo (Abstract)

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A holistic approach to facility protection from adventitious agents – A case study, Matthew Osborne, Ronan Kelly, Ann Maria McCrohan, and Marie Murphy (Abstract)

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Nanofiltration as an effective means to prevent virus contamination of cell culture processes, Christina Carbrello (Abstract)

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The oxygen binding protein, HEMOXCell(R), increases CHO cell growth and extends viability by enhancing oxygen delivery, Katrin Braasch (Abstract)

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The differential polarizability of CHO cells can be used to monitor changes in metabolism, Katrin Braasch (Abstract)

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Development of antibody detection methods for active product at the cell culture stage, Gregory Walsh, Matthew Schraut, Jon Barricelli, and Lada Laenen (Abstract)

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Development and application of glycosyltransferases for in vitro glycoengineering, Alfred Engel (Abstract)

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Improvement of CHO specific productivity using amino acid derivatives, Aline Zimmer, Caroline Hecklau, Sascha Pering, Alisa Schnellbaecher, and Thomas Eichhorn (Abstract)

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Deepening Knowledge on CHO cells metabolism using multiple tracer substrates, Ana Teixeira and Manuel Carrondo (Abstract)

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NMR-based design of chemically-defined protein-free feed medium for the CHO expression system, Marina Goldfeld (Abstract)

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How to select the most suitable media for your cells, Marcella Dalm (Abstract)

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Comparison of commercial CHO cell media formulations using material-oriented recurrent spectral libraries, Kelly Telu (Abstract)

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Using definitive screening design to effectively assess the combinatorial impacts of media supplements on monoclonal antibody production in mammalian cells, Aaron Chen (Abstract)

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Integrating emerging trends in upstream process development: Autosampling, nutrient feedback control, and single use tanks, T. Craig Seamans (Abstract)

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Implementation activities for a chemically-defined media platform to minimize media variability impact to cell culture performance and product quality, Martin Gawlitzek, Brian Wong, Robert Shawley, and Masaru Shiratori (Abstract)

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Development of a chemically defined media and a chemically defined feeding strategy for extended growth and enhanced productivity in CHO-K1 and CHO DG44 cultures, Sagar Kokal, Kyle Liu, and John Menton (Abstract)

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Evaluation of performance enhancing effects of supplementation with complex feed system and supplements with Sheff-CHO CD complete media in CHO-K1 and CHO DG44 cultures, John Menton, Kyle Liu, and Sagar Kokal (Abstract)

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Incidence and potential implications of methylglyoxal in industrial cell culture revisited, Frank Chaplen (Abstract)

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An addition of lithium chloride improves the transient gene expression yield in CHO cells, Che Kim, Tae Kwang, and Gyun Lee (Abstract)

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Anti-oxidant addition to CD-CHO media to prevent damage induced by UV disinfection, Emma Dare (Abstract)

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Development of an enriched CHO feed media for quality therapeutic antibody production from high performing clones, David Ho (Abstract)

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Fed-batch process development using metabolically efficient CHO cells, Cecile Toussaint (Abstract)

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Adaptation of CHO metabolism to long term phosphate limitation, Mugdha Gadgil (Abstract)

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Separation of IgG glycoforms for biosimilars development using Fc gamma receptors as affinity-based chromatography ligands, Austin Boesch (Abstract)

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Building QbD frameworks retrospectively for commercial products and the use of scale-down model qualification strategies to support continuous improvement, Jose Menezes, Francisca Gouveia, and Pedro Felizardo (Abstract)

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Moving from a bioreactor scale-up/scale-down approach to a more holistic operational design space view, Gene Schaefer, Rick Yeager, and Ted DeLoggio (Abstract)

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Retrospective implementation of quality by design for legacy commercialized enzyme replacement therapies, Anup Agarwal and Eric Hayduk (Abstract)

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Accelerated bioprocess characterization by data enrichment in scale-down models, Viktor Konakovsky, Graham McCreath, and Jarka Glassey (Abstract)

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Antibody production with site-specific non-natural amino acid incorporation for generation of antibody drug conjugates, Alyssa Powell (Abstract)

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Conference Program, Kathy Chan (Conference Proceeding)