Rapid and iterative deep mutational scanning via selection campaigns enables AI-assisted enzyme engineering

Authors

• Gol Mohammad Dorrazehi, AstraZeneca, UKFollow
• Matthew Penner, Department of Biochemistry, University of Cambridge, Cambridge, UK.
• Joe Perkins, Biologics Engineering, Oncology R&D, AstraZeneca, The Discovery Centre, Cambridge Biomedical Campus, UK
• Monika Papworth, Biologics Engineering, Oncology R&D, AstraZeneca, The Discovery Centre, Cambridge Biomedical Campus, UK
• Florian Hollfelder, Department of Biochemistry, University of Cambridge, UK.

Conference Dates

October 19-24, 2025

Abstract

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Recommended Citation

Gol Mohammad Dorrazehi, Matthew Penner, Joe Perkins, Monika Papworth, and Florian Hollfelder, "Rapid and iterative deep mutational scanning via selection campaigns enables AI-assisted enzyme engineering" in "Enzyme Engineering XXVIII", John Woodley, DTU; Ditte Hededam-Welner, DTU Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/enzyme_xxviii/41