Distal mutations in a designed retro-aldolase alter loop dynamics to shift and accelerate the rate-limiting step

Authors

• Cindy Klaus, University of Ottawa, CanadaFollow
• Serena E. Hunt, University of Ottawa, Canada
• Aqza E. John, University of Girona, Spain
• Niayesh Zarifi, University of Girona, Spain
• Alec Martinez, University of California, Merced, USA
• Ferran Feixas, University of Girona, Spain
• Marc Garcia-Borràs, University of Girona, Spain
• Michael C. Thompson, University of California, Merced, USA
• Roberto A. Chica, University of Ottawa, Canada

Conference Dates

October 19-24, 2025

Abstract

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Recommended Citation

Cindy Klaus, Serena E. Hunt, Aqza E. John, Niayesh Zarifi, Alec Martinez, Ferran Feixas, Marc Garcia-Borràs, Michael C. Thompson, and Roberto A. Chica, "Distal mutations in a designed retro-aldolase alter loop dynamics to shift and accelerate the rate-limiting step" in "Enzyme Engineering XXVIII", John Woodley, DTU; Ditte Hededam-Welner, DTU Eds, ECI Symposium Series, (2025). https://dc.engconfintl.org/enzyme_xxviii/73