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ECI Digital Archives

ECI Digital Archives

    Content Posted in 2017

     

    3D-printed structured adsorbents for molecular separation, Sarah Couck, Jasper Lefevere, Steven Mullens, and Joeri F.M. Denayer

     

    Acoustic cell washing and raman spectroscopy technologies To address cell therapy bioprocess challenges, James M. Piret, Michael Smith Laboratories, Mitchell Braam, Catherine Gordon, Amarandi H. Morales, June Wong, Christopher Sherwood, Stanislav O. Konorov, Shreyas Rangan, Sepehr Kamal, H. Georg Schulze, Timothy Kieffer, Michael W. Blades, and Robin F.B. Turner

     

    Adsorption equilibrium and kinetics of high molecular weight n-paraffins mixtures and kerosene on 5A zeolite, Daniel Aranda, Vicente Ismael Águeda, José Antonio Delgado, María de los Ángeles Uguina, Marcin Tomasz Holik, Javier Peláez, Jesús Javier Lázaro, and Ignacio David López

     

    Adsorption of representative pharmaceutical compounds from hospital wastewater by carbon materials, S. Álvarez-Torrellas, V.I. Águeda, D. Aranda, G. Ovejero, and J. García

     

    Adsorptive removal of CO2 from CO2-CH4 mixture using cation-exchanged zeolites, Jong-Nam Kim, Hyung Chul Yoon, Joo Hyun Park, Kanghee Cho, Sang Sup Han, Hee Tae Beum, and Dong Woo Cho

     

    Advanced RO element obtained by new membrane and channel material, Hiroyuki Yamada, Takafumi Ogawa, and Masahiro Kimura

     

    Aggregation kinetics of human mesenchymal stem cells under wave motion, Teng Ma, Ang-Chen Tsai, Yijun Liu, and Ravindran Chella

     

    Albumin in cell culture media – An examination of quality and function, Randall W. Alfano

     

    Altering, Improving, And Defining The Specificities Of Crispr-Cas Nucleases, Benjamin P. Kleinstiver, Michelle S. Prew, Nhu T. Nguyen, Moira M. Welch, J. Keith Joung, Shengdar Q. Tsai, Vikram Pattanayak, and Martin J. Aryee

     

    A mechanistic model of erythroblast growth inhibition: Optimising red blood cell manufacture, Katie Glen, Forhad Ahmed, Rachel Bayley, Robert Thomas, and Adrian Stacey

     

    A method for estimating capital investment and facility footprint of cell therapy facilities, Tania Pereira Chilima, Thierry Bovy, Fabien Moncaubeig, and Suzanne S. Farid

     

    An alternative methodology for a quantitative flow-based cell-mediated in vitro cytotoxicity assay to evaluate immune cell potency, Sherry Zhou, Ryan Shorr, and Brian Murphy

     

    Analytical affinity chromatography-on-a-chip for selective capture and sensitive detection of protein and polynucleotide biomarkers, Ruben R.G. Soares, Catarina R.F. Caneira, Narayanan Madaboosi, Virginia Chu, Inês F. Pinto, Ana M. Azevedo, M. Raquel Aires-Barros, and João P. Conde

     

    A novel acoustic cell processing platform for cell concentration and washing, Bart Lipkens, Chris Leidel, Jason Dionne, and Brian Dutra

     

    A novel high temperature and flame resistant Twaron aramid foam, Ruud Heijmans

     

    Antimicrobial chitosan foams with and without polyester blending as tissue engineering scaffolds, Lukas Gritsch and Aldo R. Boccaccini

     

    A penny today or a dollar tomorrow – early stage development for future success, Nick Timmins

     

    Application of quality by design concepts and automation to improve manufacturing process consistency of development and clinical-stage cell therapies, Peter Mitchell, Mark McCall, Robert Thomas, and Kieran O’ Donovan

     

    Application of the migratory nature of human mesenchymal stem cells to optimise microcarrier-based expansion processes, Steven Ruck, Karen Coopman, Chris Hewitt, and Alvin Nienow

     

    Appraisal of microcarrier suspension dynamics in shaken bioreactors, Gregorio Rodriguez, Martina Micheletti, and Andrea Ducci

     

    Assay automation towards the commercialization of cell therapies, Kruti Shah

     

    A Systems Approach For Car T Cell Therapy Product Characterization, Sadik H. Kassim

     

    Bespoke cell therapy manufacturing platforms - a contradiction in terms?, Eytan Abraham, Yonatan Levinson, Inbar Friedrich Ben-Nun, and Yaling Shi

     

    Beyond glass microspheres, high strength, high temperature hollow shells, Carol Wedding, Peter Marshall, and Adeline Miermont

     

    Bienzymatic production and reaction-integrated separation of laminaribiose by ad- and desorption on zeolite BEA, Dave Hartig, Karl Vorländer, and Stephan Scholl

     

    Bioprocess integration for human mesenchymal stem cells: from up to downstream processing scale-up to cell proteome characterization, Margarida Serra, Bárbara Cunha, Tiago Aguiar, Sofia B. Carvalho, Marta M. Silva, Ricardo A. Gomes, Manuel J. T. Carrondo, Patrícia Gomes-Alves, Cristina Peixoto, and Paula M. Alves

     

    Biorefinery to produce activated carbon from biomass - an approach for a biogas refining process, Isabel Esteves, Nuno Lapa, Elena Surra, Suzanna Lancinha, Maria Bernardo, Isabel Fonseca, Rui Ribeiro, and José Paulo Mota

     

    Carbon dioxide separation from anaesthetic gases with membrane contactors and biocompatible ionic liquids, Carla Martins, Luísa Neves, Isabel Coelhoso, João Crespo, and Carlos Afonso

     

    CAR-T manufacturing: delivering on the promise of a transformational therapy, Greg Russotti

     

    Cell Therapy Manufacturing: It's about "TIME", Donald Powers

     

    Cell Therapy Product Manufacturing Considerations, Mohammad Heidaran

     

    Challenges And Solutions To Quality Gmp Supply Of Aav Vectors, Anandita Seth and Francesca Vitelli

     

    Characterisation and process verification studies in a miniature bioreactor used as a predictive tool to scale-up an industrial process, Asma Ahmad, Martina Micheletti, Eli Keshavarz-Moore, Richard Davies, and Geoff Brown

     

    Characterization and fractionation in Aqueous Two-Phase Systems of site-specific PEGylated antibodies: Targeting stem cell separation, Marco Rito-Palomares and Mirna González-González

     

    Characterization And Optimization Of The Nanobridge System For Hesc Suspension Cultures, Peter Gray

     

    Characterization of a 3D matrix bioreactor for scaled production of human mesenchymal stem cells, Andrew B. Burns, Corinna Doris, Kevin Vehar, Cameron Bardliving, M. Ian Phillips, and Parviz Shamlou

     

    Characterization of interfacial strength of syntactic foam by unit cell finite element model, W.J. Lee, Y.J Kang, and Y.C. Lee

     

    Clinical Scale Manufacturing Of Autologous Insulin Producing Liver Cells For The Treatment Of Diabetes, Rachel Legmann, Andy Reniers, Nicholas Kohlstrom, Brian Gardell, Fabien Moncaubeig, Vered Aviv, Keren Shternhall-Ron, Irit Meivar-Levy, and Sarah Ferber

     

    CO2 capture over H2 by polymeric membranes for carbon-free H2 Production, Ikuo Taniguchi

     

    CO2 interactions with porous carbons: Is the surface stable at ambient conditions?, Teresa J. Bandosz, Mykola Seredych, and Enrique Rodriguez-Castellon

     

    Coated glass microballoons and syntactic foams thereof for environmental cleanup, K. K. Chawla and G. M Gladysz

     

    Comparison and evaluation of agglomerated MOFs in gaseous biofuels purification by means of pressure swing adsorption (PSA), José Antonio Delgado, Vicente Ismael Águeda, María de los Ángeles Uguina, Carlos A. Grande, and Pablo Brea

     

    Composite Foams as Tissue Scaffolds: Past, Present and Future, Liliana Liverani and Aldo Boccaccini

     

    Comprehensive cell manufacturing system based on flexible modular platform 85, Masahiro Kino-oka and Manabu Mizutani

     

    Computational bioseparation process development, Marcel Ottens

     

    Computational fluid dynamic modeling of 100ml and scaled-down 10ml stirred suspension bioreactors enables prediction of embryonic stem cell characteristics, Breanna S. Borys, An Le, Michael S. Kallos, Charlie Yu-Ming Hsu, Derrick E. Rancourt, and Ian D. Gates

     

    Computational fluid dynamics (CFD) approach for characterizing and improving fluid flow for membrane filtration technologies and successful scale-up, Mohd Shawkat Hussain and Yuhong Zhou

     

    Conductive nanothick gold on hydrophilic polymeric nanomembranes, Christian Schuster, Agnes Rodler, Rupert Tscheließnig, and Alois Jungbauer

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    Conference Program, Tom Brieva, William Miller, and Chris Mason

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    Conference Program, Kamalesh K. Sirkar, Steven M. Cramer, João G. Crespo, and Marco Mazzotti

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    Conference Program, Gary M. Gladysz, Krishan K. Chawla, Aldo R. Boccaccini, and Manabu Fukushima

     

    Considerations And Challenges Associated With Manufacturing Autologous Cellular Therapies Such As Car T Cells, Dawn Maier

     

    Controlling the kinetics of aluminium reaction to control the porosity of foam concrete, Ailar Hajimohammadi, Tuan Ngo, and Priyan Mendis

     

    Control of starting material and final product administration of cellular therapies, Nayyereh Rajaei, Brian Murphy, Tom Brieva, and Greg Russotti

     

    Core-shell versus inert polymer grafted adsorbents for the negative chromatography of virus-like particle, Beng Ti Tey, Micky Fu Xiang Lee, and Eng Seng Chan

     

    Cost-Effective Manufacturing Strategies For Feasible Commercialisation Of Autologous Car T-Cell Products, Tania Pereira Chilima, Thierry Bovy, Fabien Moncaubeig, and Suzanne S. Farid

     

    Crack bridging modelling in Bioglass® based scaffolds reinforced by polyvinyl alcohol / microfibrillated cellulose composite coating, Luca Bertolla, Ivo Dlouhý, Michael Kotoul, Petr Marcian, Petr Skalka, Oldrich Sevecek, James Mertens, and Nikilesh Chawla

     

    Cryogenic pressure temperature swing adsorption process for natural gas upgrade, Mariana A. Moreira, Ana M. Ribeiro, Alexandre F.P. Ferreira, and Alírio E. Rodrigues

     

    Crystal nucleation from solution: design and modelling of detection time experiments, Giovanni Maria Maggioni, Elena dos Santos, Luca Bosetti, and Marco Mazzotti

     

    Decision support tools for cost-effective bioprocess design in the cell therapy sector, Michael Jenkins, Ronald W. Fedechko, Sa V. Ho, and Suzanne S. Farid

     

    Derivation of endothelial cells and formation of microvasculature from mouse embryonic stem cells, Alan Jesús Gómez-Calderon, Juan Antonio Suárez-Cuenca, and Paul Mondragón-Teran

     

    Designing a banking scale of human induced pluripotent stem cells based on suspension time-dependent quality variations in filling and cryopreservation processes, Masashi Kagihiro, Kazuhiro Fukumori, Takuya Aoki, and Masahiro Kino-oka

     

    Design Of Novel Materials To Regulate Stem And Progenitor Cell Expansion And Differentiation, Kristi Anseth

     

    Design of structured adsorbents for aplications in gas adsorption processes - Conventional shaping vs 3D-Printed formulation, Olga Sulim, Rui Ribeiro, Isabel Esteves, Christine Antunes, Aiala Garate, Paulo Duarte, Isabel Ferreira, José Mota, and Marta Plaza

     

    Determination of an optimal formulation for CAR-T Cells: Cryopreservation studies using model T-Cells, Rachel Witts, Michael Tennant, Ken Chrobak, and Parag Kolhe

     

    Development and optimization of animal origin-free, serum-free media for human treg manufacturing, M.A. Torres-Castillo, K. Bernstroem, T. Aarvak, and A. Varela-Rohena

     

    Development of 3D cellular silicone structures using reactive inkjet printing approach for energy absorbing application, Aleksandra Foerster, Ricky Wildman, Richard Hague, Christopher Tuck, and Anna Terry

     

    Development of a chemically defined, animal-component-free ex vivo expansion process for activated human T cells, Annie Ngo and Jessie H. –T. Ni

     

    Development of a cost efficient platform for the industrial manufacturing of pluripotent stem cell derived products for cell therapy: Cell expansion is the starting point, Jahid Hassan, Ricardo Baptista, Rhys Macown, Marc-Olivier Baradez, Beata Surmacz-Cordle, Daria Popova, Celine Martin, Ilaria Schena, Evangelia Rologi, Isabel Uwagboe, Mark Bell, Nicole Nicholas, Shai Senderovich, Garikai Kushinga, Nishanthi Weeratunge, Julie Kerby, Damian Marshall, Sarah Callens, and Stephen Ward

     

    Development Of A High-Dose Engineered Tcr T Cell Manufacturing Process Using Automated Semi-Continuous Perfusion Bioreactors, Kenny Choi, Jacob Okhovat, Marianna Sabatino, and Marc Better

     

    Development of an alternative harvesting method using pH to detach adherent cells from microcarriers, Tylor Walsh, Jeff Biernaskie, Rajiv Midha, and Michael S. Kallos

     

    Development of a scale-down approach to the scalable culture of induced Pluripotent Stem Cells on microcarriers using single-use Vertical-Wheel™ bioreactors under xeno-free conditions, Carlos A.V. Rodrigues, Tiago G. Fernandes, Maria Margarida Diogo, Joaquim M.S. Cabral, Daniel Giroux, Yas Hashimura, Robin Wesselschmidt, and Brian Lee

     

    Development of a syntactic-based sandwich composite for blast- Resistance modular buildings, Karana Shah, Gary Gladysz, Vinay Mishra, and Kevan Rusk

     

    Development of carbon-based adsorbent for separation of impurities such as siloxane and ammonia from land-fill gas, Jong-nam Kim, Kanghee Cho, Hyungchul Yoon, Sang-sup Han, and Hee-tae Beum

     

    Development of downstream processing options for the commercial scale purification of stem cell derived exosomes, Ivano Colao, Randolph Corteling, Daniel Bracewell, and Ivan Wall

     

    Development of microchannel emulsification as a novel cell encapsulation technology, Karen Markwick and Corinne Hoesli

     

    Development of Silicone Room Temperature Foams for Superior Performance Applications, Leeanne Brown

     

    Directed differentiation of inner ear hair cells from mouse embryonic stem cells (E14Tg2a), Miguel Ángel Juárez Mancera, Paul Mondragón Terán, Juan Antonio Suárez-Cuenca, and Rafael Manuel Navarro-Meneses

     

    Dissolvable microcarriers for efficient cell production and recovery, Todd Sciortino, Jennifer Weber, Jeffrey Scibek, and Martial Hervy

     

    DMSO-free methods of preserving mesenchymal stem cells (MSCs) that retain high levels of post thaw function, Kathryn Pollock, Allison Hubel, David H. McKenna, Peter I. Dosa, and Andre J. van Wijnen

     

    Dynamic mechanical characterization and sustainability of polyurethane foam and natural fiber laminates, Krishnan Kanny

     

    Dynamic mechanistic modelling and controlled growth factor delivery for optimization of scalable haematopoietic cell processing, Robert Thomas, Katie Glen, Rebecca Moore, Matthew Worrallo, Elizabeth Cheeseman, and Adrian Stacey

     

    Economic and operational appraisal of an allogeneic CAR T-cell bioprocess, Michael Jenkins, Mark W. Leonard, Yajin Ni, Ronald W. Fedechko, and Suzanne S. Farid

     

    Economics and quality attributes of hMSC production in xeno-free bioprocessing media, Jon A. Rowley, Lye Theng Lock, and Iain K. Farrance

     

    Effective hypothermic storage of human pluripotent stem cell-derived cardiomyocytes compatible with global distribution of cells for clinical applications and toxicology testing, Margarida Serra, Cláudia Correia, Alexey Koshkin, Madalena Carido, and Paula M. Alves

     

    Effects of culture media and suspension expansion technologies in mesenchymal stem cell manufacturing - A computational bioprocess and bioeconomics study, Carlos A.V. Rodrigues, Cátia Bandeiras, Joaquim M.S. Cabral, Frederico C. Ferreira, and Stan N. Finkelstein

     

    Effects of production parameters on microstructure and densification of iron/glass syntactic foam by conventional powder metallurgy, Yi Je Cho, Yong Ho Park, Wookjin Lee, Young Cheol Lee, and Jeong-Jung Oak

     

    Electrochemically-mediated adsorptive processes for CO2 capture, T. Alan Hatton and Sahag Voskian

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    ElectroOsmoDialysis, Andriy Yaroshchuk, Mykola Bondarenko, Emiliy Zholkovskiy, and Trond Heldal

     

    Enabling human pluripotent stem cell derived megakaryocyte, Elizabeth Cheeseman, Katie Glen Loughborough University, Rebecca Moore, Mark McCall, Robert Thomas, Thomas Moreau, Cedric Ghevaert, and Adrian Stacey

     

    Enabling Technology For Scalable Manufacturing Of Cell Therapy Products, Brian Lee, Yas Hashimura, Seda Karamil, Francisco Rosello, Kenny Cruz, Nathan Starkweather, Robin Wesselschmidt, and Mattew Croughan

     

    Engineering stem cell fate for drug development and therapy, Peter Zandstra and Guy Sauvageau

     

    Enginnering cardiac tissue using human induced pluripotent stem cell derivatives: Proteomic characterization of co-cultures of cardiomyocytes and endothelial cells, Bernardo Abecasis, Susana Rosa, Pedro Gouveia, Patricia Gomes-Alves, Margarida Serra, Lino Ferreira, and Paula M. Alves

     

    Establishing the design space of a filtration-based operation for the concentration of human pluripotent stem cells, Manuel JT Carrondo, Bárbara Cunha, Ricardo J.S. Silva, Cláudia Correia, Alexey Koshkin, Paula M. Alves, Margarida Serra, and Cristina Peixoto

     

    Evaluating The Quality Of Cell Counting Measurements Using Experimental Design And Statistical Analysis, Sumona Sarkar, Steven Lund, Anne Plant, and Sheng Lin-Gibson

     

    Exosomes For Regenerative Medicine – Manufacturing Challenges And Potential Applications, Ivan Wall

     

    Expansion of 3D human induced pluripotent stem cell aggregates in bioreactors: Bioprocess intensification and scaling-up approaches, Bernardo Abecasis, Tiago Aguiar, Émilie Arnault, Rita Costa, Patricia Gomes-Alves, Anders Aspegren, Margarida Serra, and Paula M. Alves

     

    Expansion strategies for human mesenchymal stromal cells cultured under xeno-free conditions, Kamilla Swiech, Patrícia Aparecida Tozetti, Samia Rigotto Caruso, Amanda Mizukami, Taisa Risque Fernandes, Maristela Delgado Orellana Hemotherapy, and São Paulo

     

    Experimental and Computational Fluid Dynamics study of microcarrier suspension during the cultivation of Mesenchymal Stem Cells in an ambr250 bioreactor, Qasim A. Rafiq, Marco C. Rotondi, Alvin W. Nienow, Christopher J. Hewitt, Neil Bargh, John Betts, and Ngibuini Mwai

     

    Experimental and economic evaluation of different culture systems for mesenchymal stromal/stem cell expansion for clinical applications, Kamilla A. Swiech, Amanda Mizukami, Tania D. Pereira Chilima, Maristela D. Orellana, Dimas T. Covas, and Suzanne S. Farid

     

    Failure behaviour of glass-microballoons/thermoset-matrix syntactic foams subject to hydrostatic loading, Lorenzo Bardella, Giovanni Perini, Andrea Panteghini, Nikhil Gupta, Maurizio Porfiri, and Noel Tessier

     

    Foams in composite structures: Past, present and future, Michael Gromacki

     

    Functional Foams, Krishan Chawla

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    Gene Therapy For Inherited Blood Diseases, From Viral Vectors To Gene Editing, Fulvio Mavilio

     

    H2 pressure swing adsorption for IGCC power plant and techno-economic analysis of integrating PSA to IGCC with carbon capture, Chang-Ha Lee, Dong-Kyu Moon, Woo-Sung Lee, and Hyun-Taek Oh

     

    High density culture of human induced pluripotent stem cells through the refinement of medium by dialysis in suspension, Suman Chandra Nath and Masahiro Kino-oka

     

    High Density Ex Vivo Expansion Of Stem Cell Aggregates In Stirred Perfusion Bioreactors, Ernesto Scibona, Daniel Karst, and Massimo Morbidelli

     

    High density polyethylene matrix syntactic foams: Industrial scale fabrication and mechanical properties, Nikhil Gupta and M. Doddamani

     

    Holistic development of a low-energy ammonia-based process for CO2 capture with solid formation, Marco Mazzotti, Daniel Sutter, Federico Milella, José-Francisco Pérez-Calvo, and Matteo Gazzani

     

    How to use computational fluid dynamics in the development of cell therapeutics ?, Valentin Jossen, Regine Eibl, and Dieter Eibl

     

    Hybrid process for genotoxics removal from active pharmaceutical ingredients combining organic solvent nanofiltration with polybenzimidazole adsorbents, Flávio Alves Ferreira, Teresa Esteves, and Frederico Castelo Ferreira

     

    Impact of high extracellular lactate on induced pluripotent stem cell metabolism and pluripotency, Daniel C. Odenwelder and Sarah W. Harcum

     

    Impact of metal substitution on stability and adsorption properties of MOF- 74, Krista S. Walton and Yang Jiao

     

    Impact of the hydrodynamic environment on cardiomyocyte differentiation of iPSC, Martina Micheletti, Jasmin Samaras, Andrea Ducci, Claudia Correia, Paula Alves, and Margarida Serra

     

    Implications Of The Caacb Virus Contamination In Biomanufacturing Project For Cell Therapy Manufacturers, Paul W. Barone, Michael E. Wiebe, James C. Leung, and Stacy L. Springs

     

    Improving production and maturation of cardiomyocytes derivedfrom human pluripotent stem cells: An “-Omics” driven approach, Margarida Serra, Cláudia Correia, Alexey Koshkin, Patrícia Duarte, Ana Teixeira, and Paula M. Alves

     

    Improving production of retroviral vector from Pg13 cells for T cell therapy, Joseph Shiloach, Sarah Inwood, Michael Betenbaugh, and Steve Feldman

     

    Incorporating Quality In Engineered Tissues Using Bottom-Up Niche Assemblies, Ioannis Papantoniou, Gabriella Nilsson Hall, Luis Mendes, Liesbet Geris, and Frank P. Luyten

     

    Industrially-relevant examples using a data analytics strategy to effectively address complex performance challenges, Lisa Graham

     

    Industry Challenges And Questions For Regulatory Authorities, Bernadette Keane

     

    Influence of glass hollow microsphere fillers on the Rheological behavior of Epoxy resin, Y.J. Kang, G. J. Jang, K. C. Lee, W. J. Lee, and Y. C. Lee

     

    Integrating Nanomembrane Separation with Plasmonic Detection for Real-Time Cell Culture Monitoring, Stephan Hinterberger, Agnes Rodler, Rupert Tscheliessnig, Luke P. Lee, and Alois Jungbauer

     

    Integration of continuous precipitation, crystallization and flocculation of recombinant proteins, Alois Jungbauer

     

    Interactive visualization of cell expansion process performance, Toon Lambrechts, Maarten Sonnaert, Jan Schrooten, Frank P. Luyten, Jean-Marie Aerts, and Ioannis Papantoniou

     

    Investigating the requirement for dual cell co-culture platforms in creating regenerative cell therapies for CNS injury, Rachael Wood, Melanie Georgiou, and Ivan Wall

     

    Large-scale stem cell production system by newly designed bioreactor, Hideaki Kagawa, Shun Goto, Mika Mifune, Soichi Kohashi, Tetsuya Yoshida, and Hidekazu Yamazaki

     

    LYTAG-driven purification strategies as a key to integrate and intensify the downstream processing of monoclonal antibodies, Ana M. Azevedo, Isabel Campos-Pinto, Sara A.S.L. Rosa, Rajesh Gavara, Marcelo Fernández-Lahore, Miguel Arévalo-Rodriguez, and M. Raquel Aires-Barros

     

    Magnetic Ratcheting Cytometry Towards Manafacturing Scale Separations Of “Best In Class” Cart-T Cells, Coleman Murray, Edward Pao, Ximin Chen, Yvonne Chen, and Dino Di Carlo

     

    Maintenance of stemness and optimization of differentiation potentials during in vitro expansion of human adipose-derived stem cells, EunAh Lee, Jungsun Lee, and Tongin Oh

     

    Manufacturing solutions for robust cell therapy expansion and harvest, Sandhya Punreddy, Julie Murrell, Samantha Luther, Tristan Lawson, Aletta Schnitzler, and Martha Rook

     

    Mass transfer simulation for concentration of kiwi juice by osmotic distillation using finite volume method, Carlos E. Zambra

     

    MaxCyte scalable electroporation: A universal cell engineering platform for development of cell-based medicines from R&D to clinic, Jessica McClure-Kuhar, Joseph Abad, Linhong Li, Pachai Natarajan, Madhusudan Peshwa, Jessica Carmen, and Krista Steger

     

    Mechanism of preferential CO2 permeation of amine-containing polymeric membrane, Mai Yoshizawa

     

    Membrane distillation for treating hydraulic fracturing produced waters, S. Ranil Wickramasinghe and Kamyar Sardari

     

    Membrane supports designed for Pd membranes, Olivia Barron, Cordelia Sita, Bernard Jan Bladergroen, and Vladimir Linkov

     

    Metabolism Regulation Of Phenotypic And Therapeutic Properties Of Human Mesenchymal Stem Cells, Teng Ma, Yijun Liu, Ang-Chen Tsai, and Xuegang Yuan

     

    Metabolomics And The Role Of Metabolism In Stem Cell Bioprocessing, Athanasios (Sakis) Mantalaris

     

    Metal coating of ceramic microspheres: A new precursor for realising metal-based syntactic foams, Andrei Shishkin, Maria Drozdova, Irina Hussainova, Dirk Lehmhus, Mark Lisnansky, and Vjaceslavs Lapkovskis

     

    Microfluidic tools and high-content imaging for cell therapy bioprocessing, Ana Valinhas and Ivan Wall

     

    Miniaturization of aqueous two-phase extraction for biological applications, Raquel Aires-Barros, Ruben R.G. Soares, Maria Joao Jacinto, Daniel Silva, Virginia Chu, Ana M. Azevedo, and João P. Conde

     

    Modelling of metal-organic frameworks as tunable adsorbents for separations, Randall Q. Snurr

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    Modification of T lymphocytes with lentiviral vectors for expression of anti-CD19 chimeric antigen receptor (CAR), Virgínia Picanço-Castro, Pablo Moço, Daianne MC Fantacini, Marcela CC Freitas, Dimas T. Covas, and Kamilla Swiech

     

    Monitoring of membrane processes with fluorescence molecular probes, João G. Crespo, Carla Portugal, Isabel Coelhoso, Santoro Santoro, Alberto Figoli, and Reyes Mallada

     

    Moving Off-The-Shelf Into Patients; Development Of Pluripotent Cell-Based Immunotherapeutics, Stewat Abbot

     

    Nanomembranes in biotechnology: Separation of small and large biomolecules, Alois Jungbauer, Christian Schuster, and Agnes Rodler

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    New adsorbers for the removal of genotoxic impurities from active pharmaceutical ingredients, Teresa Esteves, Frederico C. Ferreira, Ana I. Vicente, and Carlos A. M. Afonso

     

    New paradigm of scalable manufacturing for allogeneic cell therapy products, Brian Lee, Yas Hashimura, Seda Karamil, Francisco Rosello, Kenny Cruz, Nathan Starkweather, Robin Wesselschmidt, and Mattew Croughan

     

    NIST and FDA collaboration on standards development activities and laboratory programs supporting translation of regenerative medicine products, Sumona Sarkar and Sheng Lin-Gibson

     

    Novel Assays For Immunotherapy Product Characterisation And Potency Measurement, Damian Marshall, Moira Francois, Beata Surmacz-Cordle, Alex Chan, Assa Oumie, and Marc-Olivier Baradez

     

    Novel curative systems for high strength, low thermal conductivity epoxy-based syntactic foams, Gary Gladysz, Borys Schafran, Jeff Dimmit, Karana Shah, Benjamin Willis, and Brian Pillay

     

    On the potential of phase-change adsorbents for CO2 capture by temperature swing adsorption, Marco Mazzotti, Max Hefti, Lisa Joss, and Zoran Bjelobrk

     

    On the use of structured adsorbents in cyclic adsorption processes, James A. Ritter, Armin D. Ebner, and Nima Mohammadi

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    Opportunities for applying biomedical production and manufacturing methods to the development of the clean meat industry, Liz Specht and Christie Lagally

     

    Optimization of a scalable single-use manufacturing platform for expansion of high quality human mesenchymal stem cells, Dave Splan, Mark Szczypka, Lye-Theng Lock, and Jon Rowley

     

    Optimization of human limbal epithelial stem cell expansion under chemically defined culture conditions, Mario Antonio Tellez-Gonzalez, Juan Antonio Suárez-Cuenca, and Paul Mondragón-Terán

     

    Optimized media and workflow for the expansion of human pluripotent stem cells as aggregates in suspension, Eric Jervis, Angela McLaughlin, Kyle Hukezalie, Steven Woodside, Terry E. Thomas, Sharon A. Louis, and Allen C. Eaves

     

    Optimized process for regulatory T cell activation and expansion using Dynabeads™ Treg CD3/CD28 for clinical applications, Hui Zhang, Kerstin Bernstrom, Nora Lieske, Ida Caroline Schroder, Tuva Holt Hereng, Grethe Okern, Hilde Almaasbak, and Tanja Aarvak

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    Optimizing the regeneration process parameters for forward osmosis to produce clean water at low temperature, Abdukarem Amahmed, Adel Sharif, and Hameed B. Mahood

     

    Organic solvent nanofiltration with novel perfluoropolymer and other polymeric membranes, Kamalesh K. Sirkar, John Chau, and Prithis Basak

     

    Overview of research on graphene-based membranes, Mainak Majumder, Abozar Akbari, and Sally El Mergawi

     

    Oxidatively stable membranes for CO2 separation and H2 purification, W.S. Winston Ho, Varun Vakharia, Witopo Salim, and Michael Gasda

     

    Phosphate and plaster bonded syntactic foams for collapsible cores in light metal casting, Dirk Lehmhus, Michael Heuser, Farina Handels, and Jörg Weise

     

    Polymer-grade olefin production by gas-phase SMB, Vanessa Martins, Ana Ribeiro Ana Ribeiro, José Loureiro, Alexandre Ferreira, and Alírio Rodrigues

     

    Porous Geopolymer Components, Paolo Colombo, Giorgia Franchin, and Chengying Bai

     

    Process and equipment scale-up of controlled-rate freezing in cell therapy, Jonathan Rubin

     

    Process development approaches for expansion of adherent stem cells in microcarrier-based bioreactor culture, Kara Levine, Aletta Schnitzler, Samantha Luther, Tiffany Hood, Tristan Lawson, Manjula Aysola, Kara Der, Julie Murrell, and Martha Rook

     

    Process development of human mesenchymal stem cell microcarrier culture using an automated high-throughput microbioreactor, Qasim A. Rafiq, Alvin W. Nienow, and Christopher J. Hewitt

     

    Processing and engineering applications of structured cellular ceramics through freezing route, Manabu Fukushima, Hideki Hyuga, Chika Matsunaga, and Yu-ichi Yoshizawa

     

    Processing of the ultra-light syntactic foam material Eccostock® FFP using selective laser sintering, Petra Juskova, Christopher J. Tuck, Ruth D. Goodridge, Mark Swan, and Anna Terry

     

    Process Scale-Up And Characterization For A Cardiac Derived Cell Therapy, Rachel Smith

     

    Production of anti-cd19 car t cells to support multicenter trials evaluating Kte- c19 in b cell malignancies, Marianna Sabatino

     

    Proteins as Coating Materials on Bioactive Glass-based Composite Foams, Liliana Liverani, Jasmin Hu, and Aldo R. Boccaccini

     

    Purification of minicircles by combined enzymatic modification of miniplasmid topology and multimodal chromatography, Duarte Miguel Prazeres, Ana Rita Silva-Santos, Cláudia Alves, Michaela Šimčiková, Gabriel Monteiro, and Ana Margarida Azevedo

     

    Rapid and high-capacity MgO composites by salt-controllable precipitation for pre- combustion CO2 capture, Chang-Ha Lee, Seongmin Jin, Keon Ho, and Liu Lei

     

    Rapid human T cell expansion using gas-permeable bags in the Eppendorf New BrunswickTM S41i CO2 incubator shaker, Ma Sha, Amanda Suttle, and Stacey Willard

     

    Rapid optimization of chromatography operating conditions using a nano- liter scale column on a microfluidic chip with integrated pneumatic valves and optical sensors, Inês F. Pinto, Denis R. Santos, Ruben R.G. Soares, Virginia Chu, M. Raquel Aires-Barros, Ana M. Azevedo, and João P. Conde

     

    Recovery of butanol from model fermentation broths by adsorption on activated carbon, V. Ismael Águeda, J. Antonio Delgado, M. Ángeles Uguina, and Álvaro García

     

    Redox-based electrochemical adsorption technologies for energy-efficient water purification and wastewater treatment, T. Alan Hatton, Xiao Su, Demetra S. Achilleos, and Timothy F. Jamison

     

    Regulatory Aspects Of Manufacturing And Control Of Genetically Modified Cells, Matthias Renner

     

    Removal Of Myeloid Cells From Autologous Leukocytes Used For Chimeric Antigen Receptor (Car) T Cell Manufacturing Improves Final Product Consistency And Yields, David Stroncek, Daniel W. Lee, Marianna Sabatino, Jiaqiang Ren, Steven Highfill, and Crystal Mackall

     

    Room temperature foaming of glass powder in aqueous environment, Doğuş Zeren; Mustafa GÜDEN,; and Ufuk Ş ENTÜRK

     

    Rubbery organic frameworks-tuning the Gaz-diffusion through dynameric membranes, Mihail Barboiu

     

    Scalable and controlled presentation of surface immobilised factors from the bone marrow niche for hematopoietic cell expansion, Rebecca Moore, Katie Glen, Matthew Worrallo, and Robert Thomas

     

    Scaled-up expansion of equine cord blood mesenchymal stem cells (MSCs) from stirred suspension bioreactors to 100mL computer controlled stirred suspension bioreactors using computational fluid dynamic modeling, Erin Roberts, Tylor Walsh, Thomas G. Koch, and Michael S. Kallos

     

    Scale-out of massively parallel patient-specific cell cultures with a modified transportable conditioned cell culture chamber, Alicia D. Henn, Kayla Nolan, Shannon Darou, and Randy Yerden

     

    Scaling up a chemically-defined aggregate-based suspension culture system for neural commitment of human pluripotent stem cells, M. Margarida Diogo, Cláudia C. Miranda, Tiago G. Fernandes, and Joaquim M.S. Cabral

     

    Selective manipulation of crystal shape by combined crystallization, milling, and dissolution stages - An approach for robust process design, Fabio Salvatori, Ashwin Kumar Rajagopalan, Stefan Bötschi, Janik Schneeberger, and Marco Mazzotti

     

    Selectvie Modification of Membrane Pore and External Surfaces, S. Ranil Wickramasinghe, Blaine M. Carter, Anh Vu, and Xianghong Qian

     

    Sequencing synthesis and crystallization to improve product yield, Ronald Rousseau, Andreas Bommarius, Matthew McDonald, and Luis Encarnacion-Gomez

     

    Shear susceptibility of human mesenchymal stem cells increases with generation number: Implications for stem cell therapy scale-up and manufacturing, Peter Amaya, Eric Plencner, James Kim, Will Heydinger, Jeffrey Chalmers, Peter Rapiejko, and Jane Ring

     

    Strain rate properties of syntactic foams, Nikhil Gupta

     

    Surface engineering for developing new membrane adsorbers, S. Ranil Wickramasinghe, Anh Vu, and Xianghong Qian

     

    Synthesis of energy efficient separation processes using distillation and membranes, Rakesh Agrawal

     

    Synthesis of functionalized membranes for metal capture to tunable separations, D. Bhattacharyya, S. Hernandez S. Hernandez, A. Saad, and A. Colburn

     

    Tailored surface porosities on ceramic foams, Manabu Fukushima, Akihiro Shimamura, Tatsuki Ohji, and Naoki Kondo

     

    The development of scalable bioreactor series for human iPS cell stirred suspension culture, Masanori Wada, Yoichi Ishikawa, Katsuhisa Matsuura, and Masahiro Kino-oka

     

    Thermoplastic syntactic foam-based composite tornado shelter: fabrication and characterization, Brian Pillay

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    Thin film membranes for molecular separations, Andrew Livingston

     

    Total Quality Approach To Cell Incubation And Processing / Scale-Up & Scale-Out, Kevin Murray

     

    TRPV-1 activation through thermal and agonist treatment in the process of scalable cardiac differentiation and tissues fabrication is the novel strategy to eliminate undifferentiated iPS cells in the bioengineered cardiac tissues, Katsuhisa Matsuura

     

    Two-column relay simulated moving-bed for gas-phase separations, Rui P. P. L. Ribeiro, Isabel A. A. C. Esteves, and José P. B. Mota

     

    Umbilical cord matrix derived-mesenchymal stem cell production in microcarrier- based culture systems, Ana Fernandes-Platzgummer, António M. de Soure, Yi-Feng Huang, William Milligan, Amanda Mizukami, Kamilla Swiech, Cláudia L. da Silva, and Joaquim M.S. Cabral

     

    Understanding and enhancing selective Fab separations using multimodal chromatography, Steven Cramer

     

    Unveiling human Cardiac Stem Cells regenerative potential in Ishemia/Reperfusion Injury, Margarida Serra, Maria João Carvalho Sebastião, Rute Pereira, Patrícia Gomes-Alves, Paula Marques Alves, and Itziar Palacios

     

    Use of expanded bed chromatography in industrial scale enzymes production, Guilherme N.M. Ferreira and Esteban Freydell

     

    Utilizing simulation and optimization techniques to evaluate different CAR T cell therapy manufacturing paradigms, Jon C. Gunther, Olga Raskina, and Christopher G. Ramsborg

     

    Voids in Materials: Adding Functionality during Additive Manufacturing, G. M Gladysz and K. K. Chawla

     

    Why nanofibers are a good adsorptive surface – fundamental understanding and industrial applications for mAb bioprocessing, Karol Lacki, Ian Scanlon, Oliver Hardick, Will Lewis, and Daniel G. Bracewell

     

    XENO-Free production and recovery of human pluripotent stem cells using synthetic dissolvable microcarriers, Maria Margarida Diogo, Sara M. Badenes, Sara F. Vieira, and Joaquim M. S. Cabral

 
 
 

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