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    Content Posted in 2022

     

    2-stage continuous growth-decoupled biomolecules production using Escherichia coli – Towards microbial small-footprint manufacturing, Juergen Mairhofer, Patrick Stargardt, Lukas Feuchtenhofer, Florian Weiss, Florian Strobl, Florian Simon, and Gerald Striedner

     

    7D-Grid-AI-Technology: A technology that translates enzymes from a computer to business with limited lab experiments, Pravin Kumar, Gladstone Sigamani, and Roopa L

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    A biotechnological strategy for the valorization of cellulose through Levoglucosenone, Louis Mouterde, Florent Allais, and Jon D. Stewart

     

    About the measurement of restoration kinetics in metals using the HTSI method, Gabrielle Tiphene, Paul BARAL, Claire MAURICE, Gaylord GUILLONNEAU, Jean-Michel BERGHEAU, Guillaume KERMOUCHE, and Jean-Luc LOUBET

     

    A case study: Scale up from bench to 500L of a biologics continuous manufacturing process, Sarwat Khattak and Jennifer Zhang

     

    Accelerate process development and transfer for the implementation of integrated continuous biomanufacturing, David Garcia, Nuno Carinhas, Mengyao Li, Aleksandr Pogodaev, Jörg Altekrueger, Thorsten Lorenz, and Tanja Hernandez

     

    Accelerating adenovirus manufacturing by perfusion-based process optimization, Piergiuseppe Nestola, Carina C D Joe, Nitin Chopra, Julia Niemann, Steffi Scholze, Yuanyuan Li, Rameswara R Segireddy, and Alexander D Douglas

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    Accelerating and intensifying manufacturing to enable large-scale supply of a new adenovirus-vectored vaccine within 100 days, Sandy Douglas, Alexander D Douglas, Carina C D Joe, Rameswara R Segireddy, Adam Berg, Yuanyuan Li, Dimitrio Doultsinos, Cathy Oliveira, Asma Ahmad, Nitin Chopra, Steffi Scholze, Piergiuseppe Nestola, and Julia Niemann

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    Acceleration of vaccine development by improvement of process understanding - Analysis of the host cell proteome, Roxana Disela, Daphne Keulen, Geoffroy Geldhof, Olivier Le Bussy, Martin Pabst, and Marcel Ottens

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    Accurate and precise viral quantification for rapid vaccine development in- process production monitoring using Radiance® Laser Force CytologyTM, Christof Hasse, Zachary L. Evans, Colin G. Hebert, and Sean J. Hart

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    Accurate, scalable microfermentation screening for microbial cell line development of therapeutic proteins, Erik Nordwald, Robert Todd, Tyler Telander, Aaron Pilling, and Julius Johnson

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    Accurate scaleable microfermentation screening for microbial cell line development of therapeutic proteins, Erik Nordwald, Robert Todd, Tyler Telander, Aaron Pilling, and Julius Johnson

     

    A cell-free platform for the directed evolution of toxic enzymes and proteins, Will Shindel, Erika Milczek, and Robert DiCosimo

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    A chalcone synthase-like bacterial protein catalyzes heterocyclic c-ring cleavage of naringenin to alter bioactivity against nuclear receptors in colonic epithelial cells, Ebru Ece Gulsan, Farrhin Nowshad, Stephen Safe, Meredith Leigh Davis, Jimmy Walter Crott, Arul Jayaraman, and Kyongbum Lee

     

    A comparative study of phase evolution in YSZ powders, pellets and free-standing air plasma sprayed thermal barrier coatings, Vikram Hastak, Edward J. Gildersleeve, Sanjay Sampath, and Ashutosh S. Gandhi

     

    A Coupled Thermal and Mechanical Analysis of Sintering in Thermal Barrier Coatings Under Gradient Exposure, John Saputo and Sanjay Sampath

     

    A coupled thermal and mechanical analysis of sintering in thermal barrier coatings under gradient exposure, John Saputo and Sanjay Sampath

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    Adapting Flublok/supemtek® recombinant protein expression systems to Sars-cov-2, Steven Hauser, Val Mermall, Nikolai Khramtsov, and Ronald Neeleman

     

    Additive manufacturing enabling W-SiC and W-ZrB2-SiC heterogeneous materials, David Mitchell, Trevor Aguirre, Corson Cramer, Austin Schumacher, Michael Kirka, Christopher Ledford, and Vlastamil Kunc

     

    Additive manufacturing of chopped fiber ultra-high ceramic composites, Lisa Rueschhoff, Benjamin Lam, Elizabeth Malek, William Costakis, Connor Wyckoff, and James . William Kemp

     

    Additive micromanufacturing and dynamic characterization of copper microlattices, Rajaprakash Ramachandramoorthy, Szilvia Kalácska, Amit Sharma, Manish Jain, Sung-Gyu Kang, Jakob Schwiedrzik, Xavier Maeder, and Johann Michler

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    Addressing the pain-points of single-use intensified multi-product downstream and liquid processing in a dancefloor production room layout, Stuart Tindal, Ganesh Kumar, Fritjof Linz, Michael Koch, Fabien Rousset, David Johnson, Franziska Froboese, and Geert Lissens

     

    A deep learning tool for protein engineering, Huimin Zhao

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    Adenovirus-based vaccine platform for mucosal or parenteral immunization of chickens, Omar Famos Villar

     

    A dual platform revolutionizing gene therapy manufacturing, Tania Pereira Chilima

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    Advanced control strategies for the continuous production of monoclonal antibodies, Markus Kampmann, Thomas Kruse, Johannes Lemke, David Pollard, and Jonas Austerjost

     

    Advanced database mining integrating sequence and structure bioinformatics with microfluidics challenges enzyme engineering, Zbynek Prokop, Jiri Damborsky, Antonin Kunka, David Kovar, Pavel Vanacek, Michal Vasina, David Bednar, Jiri Hon, Hana Faldynova, Stanislav Mazurenko, Tomas B uryska, Stavros Stavrakis, Andrew deMello, Christoffel P. S. Badenhorst, and Uwe T. Bornscheuer

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    Advanced Imaging and Analysis Applications in Organ-on-Chip Technology, Sepand Bafti

     

    Advanced manufacturing process design for Mesenchymal Stromal Cell therapies, Bryan Wang, Annie Bowles-Welch, Bharat Kanwar, Walker Byrnes, Zhaonan Liu, Chuck Zhang, Stephen Balakirsky, Carolyn Yeago, and Krishnendu Roy

     

    Advanced process control and process analytical technology for continuous bioprocessing, Lukas Kuerten, Sean Ruane, Bethany Kerr, Daniel Myatt, Vicki Linthwaite, Craig Manning, Harvey Branton, and Simon Hawdon

     

    Advanced process control strategies for continuous influenza viral particle production, Pavan Inguva, Kaylee C. Schickel, and Richard D. Braatz

     

    Advanced Thermochemical Conversion of Various Waste Feedstocks with CCS for Clean Hydrogen Production - a Life Cycle Assessment, Suviti Chari, Alex Sebastiani, Gema Amaya-Santos, Andrea Paulillo, Paola Lettieri, and Massimiliano Materazzi

     

    Advanced Thermochemical Conversion of Various Waste Feedstocks with CCS for Clean Hydrogen Production ‐ a Life Cycle Assessment, Suviti Chari, Alex Sebastiani, Gema A maya-Santos, Andrea Paulillo, Paola Lettieri, and Massimiliano Materazzi

     

    Advances and challenges in the development of UHTCMCs - A review of the C3harme project, Diletta Sciti and L. Zoli

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    Advances in bioprocessing, analytics and formulation of influenza HA-VLP vaccine candidates produced by insect cells, António Roldão, Ricardo Correia, Bárbara Fernandes, Sofia B. Carvalho, Ricardo J. S. Silva, and Cristina Peixoto

     

    Advances in hollow fiber membrane technology for high density perfusion cell culture, Jessica McRoskey, Tristan Winneker, Thomas Lazzara, Christian Julien, and Thomas Vandromme

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    Advances in therapeutic HIV vaccine development, Christian Brander

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    Advancing preclinical in vitro pulmonary models for ventilation and Inhalation assays, Josue Sznitman

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    Advancing vaccine development and manufacture in Africa, Ebrahim Mohamed and Patrick Tippoo

     

    Advantage of high turndown SUB for intensified process, Edward Chan

     

    Adventures on the routes of enzyme evolution – In memoriam Dan Tawfik, Nobu Tokuriki

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    Affinity purification of SARS-COV-2 spike protein receptor binding domain produced in a C1 fungal expression system, Amit Dutta, Aditya Utturkar, Ronen Tchelet, Noelia Valbuena Crespo, Laura Mueller, and Renaud Jacquemart

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    Affinity resins enable a multi-vaccine/platform purification process and rapid response to new viruses, Warren Kett and Kent Hallenbeck

     

    A fluorescent optical ammonia sensor - Suitable for online bioprocess monitoring, Maximilian Maierhofer, Veronika Rieger, and Torsten Mayr

     

    A fully continuous and modular monoclonal antibody purification process with capture via precipitation, Todd Przybycien, Andrew L. Zydney, Steven M. Cramer, and B. Wayne Bequette

     

    A geometry for quantitative analysis of interface fracture at the micron scale, Eloho Okotete, Subin Lee, Gerhard Dehm, Steffen Brinckmann, and Christoph Kirchlechner

     

    A Geoscientific Perspective on Silicate Melt Interactions with TBCs, Dirk Müller, Kai-Uwe Hess, Ulrich Küppers, Donald B. Dingwell, Gerhard Wolf, Pawel Rokicki, and Andrzej Nowotnik

     

    A high-throughput single-use platform for vaccine bioprocess development, Sarah L. Slack and Gary J. Lye

     

    A hyperstable glycosyltransferase for blue denim dyeing, Gonzalo Bidart, Natalia Putkaradze, David Teze, Leila Lo Leggio, Sumesh Sukumara, Ólafur Ögmundarson, Anna-Mamusu Sesay, and Ditte Welner

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    All doses are not the same: Potential role of vaccine quality in vaccine adverse reactions, Bruce Yu, Katharine T. Briggs, and Marc B. Taraban

     

    Alloy discovery via combinatorial and high-throughput synthesis and mechanical characterization, Adie Alwen and Andrea Hodge

     

    A mathematical framework for high strain rate nanoindentation testing, Warren Oliver, Benjamin L. Hackett, Christopher C. Walker, P. Sudharshan Phani, and George M. Pharr

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    AMBR®250 HT System: A key process development tool for new live virus and microbial vaccine candidates, Jessica Olson, Greeshma Manomohan, Alyssa Brown, Christopher Lee, Samantha Moyer, and Marc Wenger

     

    A mechanism-based approach for assessing the structural integrity of plasma-sprayed multilayer thermal barrier coatings, Matthias Oechsner, Marcel Adam, and Christian Kontermann

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    A microfluidic architecture with multidirectional diffusion for modelling the stromal compartment of pancreatic ductal adenocarcinoma, Michael Mohan and Edmond W. K. Young

     

    Amino acids and antibody N-glycosylation based on Raman spectroscopy in high cell density perfusion culture, Veronique Chotteau, Meeri E.L. Mäkinen, Andreas Castan, and Hubert Schwarz

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    An adenovirus-based vaccine manufacturing technology platform for mucosal or parenteral immunization against poultry diseases in sub-Saharan Africa, Omar Farnós, Esayas Gelaye, Samia Rourou, Alya Soudani, Khaled Trabelsi, Alice Bernier, Kumar Subramaniam, Martha Yami, and Amine A. Kamen

     

    An alternative management scheme for plastics from construction & demolition waste, Filomena Ardolino, Giovanni F. Cardamone, and Umberto Arena

     

    Analysing the environmental performance and improvement factors of plastic packaging recycling systems, Pieter Callewaert and Kari-Anne Lyng,

     

    Analysis of Different Schemes for Recovery of REE from Phosphoric Acid, Patrick Zhang

     

    Analysis of plastic waste circularity through LCA, Andres Font, Oksana Horodytska, and Dimitris Kiritsis

     

    Analysis of plastic waste circularity through LCA, Andres Font, Dimitris Kiritsis, and Andrés Fullana

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    Analytical development to support manufacturing of a sustainable vaccine against Invasive Nontyphoidal Salmonellosis, Francesca Necchi, Francesco Citiulo, Maria Grazia Aruta, Federico Pippi, Antonia De Felice, Alessandra Acquaviva, Emilia Cappelletti, Vittoria Marchetti, Danielle Carson, Sophie Myhill, Luigi Sollai, Carlo Giannelli, Daniele De Simone, Caroline Vipond, Omar Rossi, Francesco B. Scorza, Anna M. Colucci, and Rocio Canals

     

    A nature-inspired protocol to generate mature hiPSC-derived hepatocytes: Unveiling the role of human intestinal microbiome, Joana I. Almeida, Pedro Vicente, Pedro M. Baptista, and Margarida Serra

     

    An efficient microcarrier based Adeno-associated virus production method, Brian Ladd, Veronique Chotteau, and Torbjörn Gräslund

     

    An engineered cytidine deaminase for biocatalytic production of a key intermediate of the COVID-19 antiviral Molnupiravir, Ashleigh Burke, William R. Birmingha, Ying Zhuo, Thomas W. Thorpe, Bruna Zucoloto da Costa, Rebecca Crawshaw, Ian Rowles, James D. Finnigan, Carl Young, Gregory M. Holgate, Mark P. Muldowney, Simon J. Charnock, Sarah L. Lovelock*, Anthony P. Green, and Nicholas J. Turner

     

    An environmental, economic, and social evaluation of the production of animal feed from food waste: A Life Cycle Assessment, Alla Alsaleh and Esra AlEisa

     

    A new method to measure shear surface mechanical properties, Gaylord Guillonneau, Fadlallah Abouhadid, Bénédicte Adogou, Sergio Sao-Joao, Guillaume Kermouche, and Simon Breumier

     

    A new single-use disk stack separator for pilot scale CHO cell-based antibody productions, Vivian Ott, Jan Müller, Regine Eibl, Dieter Eibl, Cedric Schirmer, Rüdiger Göhmann, and Andreas Biewald

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    An LCA-based performance indicator for plastic packaging waste management systems, Sarah Schmidt and David Laner

     

    An LCA‐based performance indicator for plastic packaging waste management systems, Sarah Schmidt and David Laner

     

    A novel indentation size effect analysis to quantify material damage for safer nuclear structural health monitoring, Rohit Sharma, Nigel Jennett, Chris Hardie, and Alexandra J. Cackett

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    A novel SARS-CoV-2 (T Cell) vaccine candidate designed using the iVAX platform, Kirk Haltaufderhyde, Christine M. Boyle, Andres H. Gutierrez, Mayara Grizotte-Lake, Frances Terry, Bethany G. McGonnigal, Nicole Ruggiero, Leonard Moise, William D. Martin, and Anne S. De Groot

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    Apatite flotation from iron oxide apatite (IOA) tailings, Rickard Jolsterå, Eva Öberg, and Kristian Larsson

     

    A perspective on polishing operations for the continuous removal of process and product related impurities, Steven Cramer

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    A platform approach for the production of Hand, Foot, Mouth Disease vaccines, Yvonne Thomassen, Emilie Rodrigues, Aart van ’t Oever, Wouter van den Braak, and Dinja Oosterhoff

     

    Applying new technology and approaches to the analytical challenge of assessing the empty full ratio for adeno associated virus, Ian Anderson

     

    A preliminary social assessment of innovative management options for mixed and hazardous plastics waste, Filomena Ardolino, AnnaRita Palladini, and Umberto Arena

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    A quality- by- design approach for the implementation of a manufacturing license change using a qualified scale- down process model, Shari Narayanan,; Kulwinder Banger; Jasmine Fearnley; and Andrea CME Rayat

     

    A race to contain a global pandemic: The development of the Pfizer/BioNTech mRNA vaccine, Ranga Godavarti

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    A rapid response vaccine manufacturing platform as a countermeasure to epidemic threats, Tania Pereira Chilima and Héla Kallel

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    Artificially intelligent nanosensors for personalized diagnosis and monitoring, Hossam Haick

     

    A scalable bioreactor for the expansion of anchorage-dependent stem cells, Nicholas McMahon, Haruna Easterling, and Kreg Zimmern

     

    A scale-down model to investigate cell retention for continuous monoclonal antibody manufacture, Delphine Tavernier, Timothy Erlandson, Daniel Bracewell, and Andrea Rayat

     

    A simple method for pile-up correction by high-speed nanoindentation combined with optical profilometry, Marco Sebastiani, Edoardo Rossi, Marco Sebastiani, and Saqib Rashid

     

    Assessing alternate sparger configurations to mitigate supply chain risks in single-use bioreactors, Stephanie Ketcham, Alexandra N Tsoras, Calvin Leung, Michael DiFiore, Susan Egan, Jianlin Xu, Jeffrey Savard, C Eric Hodgman, and Amanda M. Lewis

     

    Assessing interaction networks within iPSC expansion bioprocessing to elucidate complexities of cellular phenotype and develop advanced process control strategies, James Colter, Breanna S. Borys, Tania So, Ian Lewis, Kartikeya Murari, and Michael Kallos

     

    Assessing social implications of circular economy by integrating circularity in S- LCA, Anna Luthin and Marzia Traverso

     

    Assessing social implications of circular economy by integrating circularity in S‐LCA, Anna Luthin and Marzia Traverso

     

    Assessing the High Temperature Performance of Refractory Metal Alloys, Bruce Pint and S. Dryepondt

     

    Assessing the sustainability of fed batch and continuous process formats for mAb manufacturing via bioprocess modeling, Caroline Mueller, Saman Salike, Megan McClure, Yvenna Chen, Priyanka Gupta, Daniel D'Aquila, Niklas Jungnelius, Lisa Connell-Crowley, and Ken Hamilton

     

    Assessment of C-type halohydrin dehalogenase stability, Nevena Milčić, Petra Švaco, Martina Sudar, Maja Majerić Elenkov, and Zvjezdana Findrik Blažević

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    Assessment of Mechanical TBC Failure in Complex Geometries, Mario Rudolphi and Mathias C. Galetz

     

    Assessment of technologies and scenarios for biogas management in Denmark, Anna Sofie Varling, Valentina Bisinella, and Thomas Højlund Christensen

     

    A study of the of ytterbium disilicates undergoing water vapour corrosion for environmental barrier coating applications, Simon McCormack, Philip J. K Withers, and Ping Xiao

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    A tale of two worlds from the ongoing pandemic – unprecedented successes and all too familiar failures, David Robinson

     

    Atrac® 922 collector for phosphate flotation, jointly developed by Nouryon and Yara, yields high performance and reduces environmental impact, Henrik Nordberg, Catherine Wretborn, Natalija Smolko Schwarzmayr, and Mikhail Golets

     

    A truly continuous counter-current downstream, Jon Coffman, Sevda Deldari, Ujwal Patil, Nikunj Sharda, Jitha Sridhar, Keith Morgan, and Irina Ramos

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    A universal Influenza B vaccine using mosaic-hemagglutinin vaccine candidates, Irene González-Domínguez, Yonghong Liu, Eduard Puente-Massaguer, Nicholas Lemus, Stefan Slamanig, Tsoi Ying Lai, Shirin Strohmeier, Madhumathi Loganathan, Jose Martínez-Guevara, Florian Krammer, Adolfo García-Sastre, Peter Palese, and Weina Sun

     

    Automated control of osmolality in a perfusion bioreactor system via in situ conductivity sensors, Amanda Ramsdell, Charles Budde, Ethan Penner, and Daryl Powers

     

    Automated microscale tools for speeding up both single use and reusable process development during pandemic scenarios, Jasmin Samaras and Martina Micheletti

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    Automated sampling in upstream process development for accelerated access to Critical Process Parameters (CPPs) and Critical Quality Attributes (CQAs), Srijana Chapagain, Rakesh Bobbala, Allyson Caron, and Khin Myint

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    Automated single-cell cloning in chemically defined medium for new suspension MDCK cell lines and scale-down of influenza A virus production into ambr®15 microbioreactors, Tilia Zinnecker, Ilona Behrendt, Maverick Lau, Angelika Hinkelmann, Kristin Thiele, Najd Badri, Diogo Araujo, Yvonne Genzel, and Udo Reichl

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    A versatile capillary gel electrophoresis methodology for in-process and final product characterization of virus-based targets, Rita Fernandes, José Escandell, Filipa Moura, Ana C.L. Guerreiro, Sofia B. Carvalho, Tiago Q. Faria, Ricardo J.S. Silva, Patrícia Gomes-Alves, and Cristina Peixoto

     

    Award Keynote, Veena Warikoo

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    Baker's yeast breeding and engineering to improve biologics manufacturing, Chris Finnis, Les Evans, Ed Louis, and Anne Henstra

     

    Basics and applications of gut bacterial lipid-metabolizing enzymes- A tribute to the late Professor Hideaki Yamada, Shigenobu Kishino, Sakayu Shimizu, and Jun Ogawa

     

    BBCircle – Life Cycle Assessment for innovative biorefinery process evaluation, Lidia Lombardi, Giulia Costa, G. Farabegoli, A. Polettini, R. Pomi, A. Rossi, and T. Zonfa

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    Benchside-to-Bedside translation of novel targets for regulating blood clots in man, Michael Holinstat

     

    Beneficiation of medium and low grade African phosphates in the context of stimulating supply, Ashma Singh

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    Beneficiation of phosphate ores using tribo-electrostatic separator, Abhishek Gupta, Lucas Rojas Mendoza, and Frank Hrach

     

    Benefits of reaction engineering in biocatalysis, Zvjezdana Findrik Blažević

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    Bioanalytical tools for the quantification of in-process and final product samples of a rotavirus vaccine, Sofia B. Carvalho, Mafalda M. Dias, Jean-Philippe Matheise, Guillaume Van Beersel, Isabelle Knott, Patrícia Gomes-Alves, and Paula M. Alves

     

    Biocatalysis and enzyme engineering – a personal view on the last three decades, Uwe Bornscheuer

     

    Biocatalytical access to amides, Erna Zukic, Christian Willrodt, Klaus Ditrich, and Wolfgang Kroutil

     

    Biocatalytic approaches to therapeutic oligonucleotide manufacture, Sarah Lovelock

     

    Biocatalytic oligonucleotide synthesis technology-BOOST, Jill Caswell

     

    Biocatalytic synthesis of nucleoside and nucleotide therapeutics, John McIntosh

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    Bioengineering bacterial protein nanocompartments as modular platforms for vaccines and drug delivery, Stefanie Frank

     

    Bioflotation of Apatite with Saccharomyces Cerevisiae in Hallimond Tube, André Carlos Silva, Elenice M S Silva, and Laura O Silva

     

    Biomanufacturing and testbed development for the continuous production of monoclonal antibodies, Dragana Bozinovski, Elizabeth M. Cummings Bende, Andrew J. Maloney, Jose Sangerman, Alexis B. Dubs, Amos E. Lu, Moo Sun Hong, Nili Persits, Anastasia Artamonova, Rui Wen Ou, Naresh Mohan, Miriam Yanira Nieves, Paul W. Barone, Jacqueline M. Wolfrum, Rajeev J. Ram, Stacy L. Springs, Richard D. Braatz, and Anthony J. Sinskey

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    Biomanufacturing technology advances enable rapid response to disease outbreaks, Tania Pereira Chilima and Marie Jourdan

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    Biomanufacturing using single use systems: Case study of fluoropolymer material, Julien Muzard, Muhammad Siddiqui, and Ross Acucena

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    Biophysical technologies in vaccines, Hervé Ponceblanc, Marco Garrido Sergio, and Stephanie Prizzon

     

    Bioprocess characterization at the micro-scale: Optical sensor integration in a novel capillary-wave micro-bioreactor, Kevin Viebrock, Lasse Frey, Dominik Rabl, Detlev Rasch, Sven Meinen, Andreas Dietzel, Torsten Mayr, and Rainer Krull

     

    Bioprocess optimization for generation of hepatocytes derived from hiPSC and its application in primary hyperoxaluria type 1 disease modelling, Joana I. Almeida, Pedro Vicente, Maren Calleja, Juan Rodriguez-Madoz, Felipe Prosper, Anders Aspegren, and Paula M Alves

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    Biosensors and biocatalysis for biorefinery and bioremediation, Neil Dixon

     

    Boosting squalene-hopene cyclase towards an industrial biocatalyst, Bernhard Hauer and Andreas Schneider

     

    Brief Introduction of Ma’aden’s Phosphoric Acid Complexes, Mohamed Belghiti Alaoui

     

    Bringing flexibility to integrated continuous biomanufacturing, Paul Randolph, Loïc Fejoz, René Reinbigler, Eugene Tung, Christopher Rode, Brian Polilli, and Roger Hart

     

    Brittle to ductile transition in metal/oxide nanolaminates on flexible substrates under uniaxial and biaxial tension, Barbara Putz, Thomas Edwards, Patrice Kreiml, Damien Faurie, Pierre-Olivier Renault, and Johann Michler

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    Building the future with on demand 3D printing, Lena Achleitner and Peter Satzer

     

    Business case for continuous mAb production with novel design strategies and enhanced control, Catarina Neves and Suzanne S. Farid

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    Caprylate production with lactate as electron donor using Megasphaera hexanoica, Byoung In Sang, Seongcheol Kang, Hyunjin Kim, Byoung Seung Jeon, and Okkyoung Choi

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    Carbon influence on the fracture toughness of transition metal carbides, Xingyuan Zhao, Maanas Togaru, Gregory Thompson, Christopher Weinberger, and Leslie Lamberson

     

    Carboxyesterase-mediated amidation, James Morrison

     

    Cathodic Arc Evaporation of MCrALY Coatings, Sebastien Guimond, Max Döbeli, Xavier Maeder, Toby Middlemiss, Jürgen Ramm, Lin Shang, and Benno Widrig

     

    Cell growth performance with a new single-use film, Diana Perez, Kimberly Mann, Stefano Berti, Patricia Kumpey, and Alison Dupont

     

    Cell Therapy Analytics: Challenges and Opportunities, Somayeh Tarighat

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    Cellular senescence in neuroinflammation, Shyni Varghese

     

    cGMP friendly single-use TFF filter for continuous biologics manufacturing, Francisco Pelaez

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    Challenges and Limitations of Processing Carbonatite Rare Earths Deposits in Brazil, Elves Matiolo, Amanda Soares de Freitas, Reiner Neumann, and Maria Clara Novaes Silva

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    Challenges and opportunities to formulate and stabilize vaccine candidates targeted for use in LMICs, David Volkin

     

    Challenges and solutions for allogeneic cell therapy manufacturing, Brian Lee, Sunghoon Jung, Yas Hashimura, Hannah Worden, Kelly Gray, Kenny Cruz, and Breanna Borys

     

    Challenges and solutions for allogeneic cell therapy manufacturing, Sunghoon Jung, Brian Lee, Yas Hashimura, Kenny Cruz, Hannah Worden, Kelly Gray, and Breanna Borys

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    Challenges in implementing single-use processing for the purification of polysaccharides, Francis DiGennaro, Nick Samuelson, and Emily Wen

     

    Challenges in the phase identification of steels using unsupervised clustering of nanoindentation data, Gerhard Dehm, Robin Jentner, James Best, and Christoph Kirchlechner

     

    Challenges of Implementing New Technologies in Future Waste Management - Example of Chemical Recycling, Martyna Solis and Thomas Fruergaard Astrup

     

    Challenges of mass transfer for perfusion cultures in single use bioreactors part 1:Oxygen, Anthony Beaney, Anita Dabek, Mikayla Olin, Anastasia Eftychidou, Natalia Papalamprou, Mauran Mahendra, Joanna Kolacz, and Colin Jaques

     

    Challenges of the workflow for integration of sensors into single-use systems, Karl Beer and Henry Weichert

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    Changes in extracellular matrix in failing human non-ischemic and ischemic hearts with mechanical unloading, Yimu Zhao

     

    Characterization of fatty acid-based collectors vis-à-vis apatite flotation in basic medium, Laurindo de Salles Leal Filho; Patrícia Helena Lara dos Santos Matai; Ricardo Neves de Oliveira; and Paulo Roberto Gomes Brandão,

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    Characterization of homologous industrial strains using continuous cultivation techniques to understand process performance variation in a platform fed-batch production process, Anthony Grippe

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    Characterization of ultra-high temperature materials produced by rapid- laser chemical vapor deposition (R-LCVD), Jeff Vervlied, Joseph Pegna, Kirk Williams, Mark Schaefer, Zachary Tobin, Jeff Vervlied, and Hill Boulevard

     

    Characterization & testing in extreme, applicable environments, Bhavesh V. Patel

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    Chromatographic tools for optimization of IVT reaction and improving mRNA purification process, Amélie Boulais, Rok Sekimik, Kristina S. Nemec, Janja Skok, Klemen Božič, Anže Martinčič Celjar, Pete Gagnon, and Aleš Štrancar

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    Clarification of cell culture broth using single use disposable BioSettlers, Dhinakar Kompala and Christopher Glascock

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    Clickable Shiga Toxin tracer for drug delivery, Natalia Karolina Danielewicz

     

    Climate change impact of the development in household waste management in China, Thomas H. C hristensen and Huimin Changb

     

    CMAS Reactive Coatings for TBCs, Margeaux Wallace, Jose Sanchez, Hrishikesh Keshavan, Ambarish Kulkarni, Nicole Piche, Julie Kuhn, Byron Pritchard, Mehmet Dede, and Bernard Bewlay

     

    Coatings for increased efficiency in compression ignition engines, John Saputo, Carl Schmidt, Sanjay Sampath, Felipe Caliari, Eric Gingrich, and Michael Tess

     

    Cold spray deposition of metallic-UHTC composites, Michael Large, Isaac M. Nault, Kristopher D. Behler, Adolfo A. Blassino, Matthew K. Dunstan, Christopher R. Weinberger, and Gregory B. Thompson

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    Collagen-mimetic peptides for delivery of therapeutics in chronic wounds healing application, Jeonming Hwang, Kristi L. Kiick, and Millicent O. Sullivan

     

    Collection System's Impact on Environmental Performance of the Waste Management System, Kari-Anne Lyng and Pieter Callewaert

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    Collective forces and migration during tissue development and invasion, Timo Betz

     

    Columnar Thermal Barrier Coatings Manufactured by Novel Laser Cladding Process, Daniel Mack, Christoph Vorkötter, Olivier Guillon, and Robert Vaßen

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    Combinatorial Fusion TAG yields powerful platform process for the production of pharmaceutically relevant proteins, Christoph Köppl, Monika Cserjan-Puschmann, Nico Lingg, and Gerald Striedner

     

    Company and assembly redundancy – a case study, Sheryl Kane, Terence Jackson, and Heather Larivee

     

    Comparative Study of Thermal Barrier Coatings by S-hvof and Eb-pvd Process, Yoshifumi Okajima and Taiji Torigoe

     

    Comparison of mechanical properties of titanium processed by ECAP: Macro vs. micro, Jan Maňák and Karel Tesař

     

    Computational fluid dynamic characterization of vertical-wheel bioreactors used for effective scale-up of human induced pluripotent stem cell aggregate culture, Breanna Borys, Tiffany Dang, Shivek Kanwar, Brian Lee, Sunghoon Jung, and Michael S. Kallos

     

    Computational study of temperature in a millimeter wave heat exchanger with an AlN:Mo Susceptor on an isothermal metal plate, Vadim Yakovlev, Stephanie A. M artin, Brad W. Hoff, and Ian M. Rittersdorf

     

    Concepts for Enhancing the Life of Environmental Coatings Systems, Jeroen Deijkers and Jeroen Deijkers

     

    Concepts for enhancing the life of environmental coatings systems, Jeroen Deijkers and Haydn Wadley

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    Conference Program, Sharon Brownlow, Sean Palecek, Damian Marshall, and Fernanda Masri

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    Conference Program, Magali Barbaroux and Martina Micheletti

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    Conference Program, Francesc Godia, Linda Hwee-Lin Lua, Charles Lutsch, and Tarit Mukhopadhyay

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    Conference Program, Andy Bommarius, Vesna Mitchell, and Doug Fuerst

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    Conference Program, Umberto Arena, Thomas Astrup, and Morton Barlaz

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    Conference Program, Daniel Butts, Carmen Carney, Carolina Tallon, Gregory Thompson, and Chris Weinberger

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    Conference Program, Patrick Zhang, Jan Miller, Laurindo Leal Filho, Erika Rova, Andre Carlos Silva, and Ewan Wingate

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    Conference Program, Brian Hazel, Uwe Schulz, Mike Maloney, Robert Vaβen, and Ram Darolia

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    Conference Program, Ana Azevedo, Jason Walther, and Rohini Deshpande

     

    Considerations of manufacturability for AAV based gene therapy products for rare diseases, Nripen Singh

     

    Constant flow rate viral clearance study of Planova™ BioEX virus removal filter and implementation into an integrated process for mAb purification, Hironobu Shirataki

     

    Continuity and change in screening for industrial enzymes and protein engineering- A tribute to the late Professor Hideaki Yamada, Yasuhisa Asano

     

    Continuous counter-current affinity colloidal purification, Jon Coffman, Keith Morgan, Irina Ramos, Sevda Deldari, and Jitha Sridhar

     

    Continuous Counter-current Dialysis (C3D) - the Future of Diafiltration, Irina Ramos, Nikunj Sharda, Irina Ramos, Jon Coffman, and Michelle Chen

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    Continuous culture reborn or revived?, Charles Cooney

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    Continuous downstream process of monoclonal antibody developed based on the process analysis/understanding and its validation, Shuichi Yamamoto, Fuminori Konoike, and Noriko Yoshimoto

     

    Continuous manufacturing of lentiviral vectors, Dale Stibbs, Pedro . Silva Couto, Qasim A. Rafiq, Andrea C. M. E. Rayat, Carme Ripoll Fiol, and Nigel B. Jackson

     

    Continuous measurement of strain rate sensitivity – A novel nanoindentation method, Hendrik Holz and Benoit Merle

     

    Continuous production of lentiviral vectors using a fixed-bed bioreactor, Dale Stibbs, Pedro . Silva Couto, Carme Ripoll Fiol, Qasim A. Rafiq, Nigel B. Jackson, and Andrea C. M. E. Rayat

     

    Continuous purification of antifungal peptide with a continuous chromatographic system based on fluidized bed technology, Lisa-Marie Herlevi, Guilherme Ferreira, and Hector Marcelo Fernandez Lahore

     

    Continuous Recovery of Phosphoric Acid and Rare-Earths Containing Particles from Phosphoric Acid Sludge Using a Decanter Centrifuge, Patrick Zhang, Austin Ladshaw, Jong K. Keum, Costas Tsouris, and Patrick Zhang

     

    Continuous vaccine purification utilizing multi-stage aqueous two-phase extraction, Caryn Heldt, Sheridan Waldack, Trisha Colling, Seth Kriz, Caryn Heldt, and Grace James

     

    Continuous virus filtration: An existing technology with a promising future, Julie Kozaili, William Rayfield, Mark Brower, Adrian Gospodarek, and Daniel Strauss

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    Contributions to a circular phosphate economy - Polyphosphate production in Saccharomyces cerevisiae, Jana Fees, Philipp Demling, Lars M. Blank, and Alexander Deiter

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    Controlling the size and linkage type of biopolymers derived from sucrose, Magali Remaud-Siméon

     

    Conversion of an intensified fed-batch to an integrated continuous bioprocess, Brian Follstad, Chris Ford, Neil Kitchen, Rob Piper, Brad Dell, and Lisa Connell-Crowley

     

    Correcting for substrate elasticity contributions in depth-sensing indentation of embedded particles, Alejandra Slagter, David Hernández Escobar, Joris Everaerts, and Léa Deillon

     

    Corrosion of E/TBCs: Chemical Interactions of Ceramic Materials with CMAS, Pierre-Jean Panteix; Michel Vilasi,; Justine Bonnal; Tuti Katrina Abdullah; François Perrudin; Eric Schmucker; Victor Szczepan; Stephane Mathieu; Carine Petitjean; and Pierre-Jean Panteix

     

    Cost and life cycle assessment of upstream monoclonal antibody production, Sara Badr, Eri Amasawa, and Hirokazu Sugiyama

     

    Critical choices in Waste LCA – A case study on the treatment of PAH-rich road debris, David Laner and Kaja Mol

     

    Critical choices in Waste LCA – A case study on the treatment of PAH‐ rich road debris, David Laner and Kaja Mol

     

    Critical review on life cycle assessment of bio-based platform molecules: sustainability metrics of novel technologies, Jorge Blanco, Sandra Martín, José Iglesias, Jovita Moreno, and María Linares

     

    Critical review on life cycle assessment of bio‐based platform molecules: sustainability metrics of novel technologies, Jorge Blanco, Sandra Martín, José Iglesias, Jovita Moreno, and María Linares

     

    CuAAC for inorganic preceramic polymer synthesis, Matthew B. Dickerson

     

    Cyclic oxidation of yttrium/ytterbium disilicate environmental barrier coatings, Bruce Pint, M. Ridley, M. Sweet, M.J. Lance, and K. A. Kane

     

    Damage Mechanism of an Environmental Barrier Coated Ceramic Matrix Composite Under Thermal and Mechanical Loadings, Thibaut Archer, Ines Hamadouche, Pierre Beauchêne, Thomas Vandellos, and François Hild

     

    Data Quality of Organic Waste Characteristics in Life Cycle Assessment of Waste Management: A Review, Nomena Ravoahangy, Olivier Schoefs, and Guillaume Majeau-Bettez

     

    Debye-Larmor high enthalpy cascade plasma gun technology to apply ceramic coatings for the turbine industry, Armando Salito, Geoffrey Darut, Marie Pierre Planche, Christian Adam, Manfred Rösli, Hanlin Liao, Claus-Daniel Armbruster, and Marco Reinger

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    Decisional tools for successful commercialisation of novel vaccine technologies, Christos Stamatis, Tania D. Pereira Chilima, Jose Castillo, and Suzanne Fraid

     

    Deformation mechanism of cerium oxide nanocubes - an in situ transmission electron microscopy study, Karine Masenelli-Varlot, Rongrong Zhang, Lucile Joly-Pottuz, Gaetan Laurens, Tristan Albaret, and Jonathan Amodeo

     

    Deformation mechanisms of hierarchically structured 2D single-crystal materials revealed by real-time high-resolution in-situ nanomechanical testing, Tyler Dolmetsch, Tanaji Paul, Lihua Lou, Benjamin Boesl, and Arvind Agarwal

     

    Deformation twinning in Cr2AlC MAX phase single crystals: A nanomechanical testing study, Christophe Tromas, Salome Parent, Anne Joulain, Hadi Bahsoun, and Gilles Renou

     

    Degradation of aluminide type bondcoats due to oxidation and interdiffusion: effect of base alloy composition, Dmitry Naumenko, Wencai Leng, Rishi Pillai, Nanxi Zheng, and Marlene Grohne

     

    Democratizing global supply of recombinant proteins, Kerry Love

     

    Demonstration of a commercial scale end-to-end continuous purification process, Chad Varner, Akshat Mullerpatan, Sushmitha Krishnan, Michael Coolbaugh, Jason Walther, Kevin Brower, and Shashi Malladi

     

    Densification of polymer glass film under combined high pressure and shear flow revealed via scanning X-ray microscopy, Graham Cross, Owen Brazil, H. Özgür Özer, Benjamin Watts, and John B. Pethica

     

    Design and evolution of enzymes for the Morita-Baylis-Hillman reaction, Amy Crossley, Rebecca Crawshaw, Colin Levy, Sarah Lovelock, Anthony Green, and Linus Johannissen

     

    Design and evolution of enzymes with non-canonical catalytic mechanisms, Anthony Green

     

    Design and optimization of membrane chromatography process for monoclonal antibody charge variant separation, Sathish Nadar, Balaji Somasundaram, Marcela Charry, Jagan Billakanti, Evan Shave, Kym Baker, and Linda H.L. Lua

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    Design considerations when scaling from 3-L to 3000-L or larger, Kenneth Lee

     

    Design & Construction of a truly continuous and fully automated process skid for the production and purification of a monoclonal antibody, Magdalena Pappenreiter, Sebastián Avelino Gómez Sánchez, and Magdalena Pappenreiter

     

    Design of an integrated continuous downstream process for emerging acid-sensitive antibodies based on a calcium-dependent protein A ligand, Joaquin Gomis Fons, Madelène Isaksson, Julia Scheffel, Sophia Hober, Anita Solbrand, and Bernt Nilsson

     

    Design of a twin-column countercurrent purification (MCSGP) unit for the polishing of an oligonucleotide sequence, Ismaele Fioretti, Thomas Müller-Späth, Richard Weldon, Sebastian Vogg, Massimo Morbidelli, and Mattia Sponchioni

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    Design of a vaccine against dengue and Zika viruses based on a mimotope of the envelope dimer epitope, Esmeralda Cuevas-Juárez, Arturo Liñan, Carolina Hernandez, Mykhailo Kopylov, Octavio T. Ramírez, and Laura A. Palomares

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    Design of mimotopes of a conserved epitope in dengue and Zika viruses for the obtention of broadly neutralizing antibodies, Esmeralda Cuevas-Juárez, Arturo Liñan, Carolina Hernandez, Mykhailo Kopylov, and Laura A. Palomares

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    Design of mimotopes of a conserved epitope in dengue and Zika viruses for the obtention of broadly neutralizing antibodies, Esmeralda Cuevas-Juárez, Arturo Liñan, Carolina Hernandez, Mykhailo Kopylov, and Laura A. Palomares

     

    Design of Ultra-High Temperature Ceramics for Oxidation Resistance, Niquana Smith, Mackenzie Ridley, Elizabeth J. Opila, and Bi-Cheng Zhou

     

    Design of ultra-high temperature ceramics for oxidation resistance, Niquana Smith, Mackenzie Ridley, Elizabeth J. Opila, and Bi-Cheng Zhou

     

    Design verification testing methodology for new Rosemount pH sensor, Jacalyn Saint Rudolph, Benjamin Arriola, Andrew Dierker, and Brandon Haschke

     

    Determination of the rate limiting step during zearalenone hydrolysis by ZenA, Sebastian Fruhauf, Andreas Hoebartner-Gussl, Jiri Damborsky, Wulf-Dieter Moll, and Zbynek Prokop

     

    Deterministic cell processing recovers >2-fold more cells, and up to 5-fold more naïve T cells, as compared to centrifugally prepared cells, Tony Ward, Yasna Behmardi, Laurissa Ouaguia, Cole Jones, Hani Rahmo, Alison Skelley, Khushroo Gandhi, and Roberto Campos-Gonzalez

     

    Developing a flexible automated continuous downstream processing system for research to clinical supply, Ben Gay, Louise Taylor, Harvey Branton, Daniele Messina, Philip Corner, John Welsh, Aude Iwaniec, Spyridon Gerontas, Martyn Hulley, Richard Krucia-Tran, Brian Keith, Tibor Nagy, and Ferran Sanchez

     

    Developing an effective scale-down model for a suspension adapted Hek293t-derived lentiviral vector stable producer cell line, Hamza Patel, Dr Peter Archibald, Professor Martina Micheletti, and Qasim Rafiq

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    Developing a novel microbial host and synthetic biology tools for valorizing waste polyethylene terephthalate and lignin-derived compounds, Tae Seok Moon, Jinjin Diao, and Yifeng Hu

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    Developing a ‘One Health’ Nipah virus vaccine to protect animal and public health, Simon P. Graham

     

    Developing a suspension transfection platform to produce adeno- associated viruses, Kory Blocker, Jason Rush, Melynda Dalzon, William Roberts, Boris Petkov, Simin Zaidi, Julie Johnston, and James Wilson

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    Developing methods for the production of antiviral VHH-Fc antibodies in Pichia pastoris for fast pandemic response, Chiara Lonigro, Loes Van Schie, Sandrine Vanmarcke, Katrien Claes, Simon Devos, Wannes Weyts, Wim Nerinckx, Bert Schepens, Xavier Saelens, and Nico Callewaert

     

    Developmental lineage of human pluripotent stem cell-derived cardiac fibroblast affects their functional phenotype, Martha Floy, Sophie Givens, Oriane Matthys, Taylor Mateyka, Charles Kerr, Alexandra Steinberg, Ana Silva, Jianhua Zhang, Ying Mei, Timothy Kamp, Brenda Ogle, Todd McDevitt, and Sean Palecek

     

    Development and industrialization of advanced biomanufacturing platform to address business needs and affordability of biologics, Christopher Hwang

     

    Development of a custom high strain rate nanoindenter for small scale mechanical characterization over a wide range of strain rates, Stefan Zeiler, Hendrik Holz, and Benoit Merle

     

    Development of a disruptive mass photometry technology for AAV empty full quantification, Maria Barreira, Lily Li, Carolina Pinto Ricardo, and Tony Bou Kheir

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    Development of affordable recombinant glycoconjugate vaccines in bacterial cells, Brendan Wren

     

    Development of a flexible and modular approach for integrated continuous biomanufacturing, Michael Coolbaugh, Chad Varner, Xhorxhi Gjoka, Matt Stundtner, Bob Flynn, Raja Jagadesan, Jason Walther, Kevin Brower, and Shashi Malladi

     

    Development of analytical assays for the characterization of gene circuit enabled cell therapies, Brett Kiedaisch, Mario Lorente, Brandon Lee, Philip Lee, and Nara Vu

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    Development of analytical characterization tools for process monitoring of adenovirus-based vaccines (ChAdOx and Ad5), Shaleem I. Jacob, John M. Hickey, Andrew Tait, Fatemeh Dastjerdi Vahid, Sarah Rouse, Joseph Barritt, Alexander Douglas, Sangeeta B. Joshi, David B. Volkin, and Daniel G. Bracewell

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    Development of an automated microscale platform for conjugate vaccine production in E. coli, Jasmin J. Samaras and Martina Micheletti

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    Development of a new magnetic bead platform for use in GMP production of mRNA vaccines, Marie Bosnes, Nini U.H. Kjus, Christopher Stensrud, Elisabeth Breivold, Ausra Kaleckiene, Axl Neurauter, and Lene Aasveen

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    Development of an innovative adenovirus-inspired self-assembling vaccine platform rapidly adaptable to coronaviruses and other emergent viruses, Christopher Chevillard, Axelle Amen, Solène Besson, Dalil Hannani, Isabelle Bally, Valentin Dettling, Salomé Gallet, Emilie Stermann, Guy Schoehn, Evelyne Gout, Daphna Fenel, Marlyse Buisson, Christophe Moreau, Pascal Poignard, Marie-Claire Dagher, and Pascal Fender

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    Development of an oral protein subunit COVID-19 vaccine to induce mucosal and systemic immune response, Elodie Burlet, Nissy Thomas, Shanna Carwell, Brett Gershman, and Garry Morefield

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    Development of a pentavalent Group B Streptococcus (GBS) glycoconjugate vaccine in Africa, Matthew Williams, Ebrahim Mohamed, Patrick Tippoo, and Seanette Wilson

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    Development of a pentavalent Group B Streptococcus (GBS) glycoconjugate vaccine in Africa, Seanette Wilson, Ebrahim Mohamed, Patrick Tippoo, and Matthew Williams

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    Development of a pneumococcal conjugate vaccine drug product: Ensuring stability, a robust manufacturing process and long-term commercial sustainability, William Smith

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    Development of a purification process for HIV-1 VLPs, from supernatant to lyophilization, Elianet Lorenzo Romero, Laia Miranda, Irene González-Domínguez, Francesc Gòdia, and Laura Cervera

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    Development of a regionalized recycling LCA collaborative tool, Arianne Provost‐Savard, Guillaume Majeau-Bettez, and Robert Legros

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    Development of a standardized multiplex Filovirus and SARS-CoV2 antibody immunoassay, Teri Ann S. Wong, Albert To, and Axel Lehrer

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    Development of a thermostable, multivalent filovirus vaccine based on recombinant subunit proteins, Axel T. Lehrer, Teri-Ann S. Wong, Michael M. Lieberman, Chih-Yun Lai, Eleanore Chuang, David Clements, Jaime Horton, Oreola Donini, Theodore W. Randolph, Kendall B. Preston, Liana O. Medina, and Thomas W. Geisbert

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    Development of a universal group 2 influenza virus vaccine using chimeric hemagglutinin constructs, Eduard Puente-Massaguer, Madhumathi Loganathan, Weina Sun, Peter Palese, and Florian Krammer

     

    Development of autologous adipose derived mesenchymal stem cell therapy: Lessons learned from treating more than 250 patients, Allan Dietz

     

    Development of cGMP manufacturing processes for the large-scale production of cell-based therapies for commercial applications, Krishna M. Panchalingam, Thomas Richardson, Mehdi Shafa, Tylor Walsh, and Behnam Ahmadian Baghbaderani

     

    Development of CMAS Resistant Thermal Barrier Coatings: Challenges and Implications, Ravisankar Naraparaju, C. Mikulla, L. Steinberg, Peter Mechnich, Uwe Schulz, Z. Stein, S. Raghavan, and L. Tetard

     

    Development of novel indentation-based stress relaxation tests to study transient plasticity in metals, Suprit Purushottam Bhusare, Aloshious Lambai, Jakob Schwiedrzik, Johann Michler, and Gaurav Mohanty

     

    Development of P450-BM3 using molecular dynamics simulations- A tribute to the late Professor Hideaki Yamada, Satoru Ishihara, Satoshi Koikeda, Jinzen Ikebe, Tomoshi Kameda, Si-Bum Park, Jun Ogawa, Shigenobu Kishino, and Ryotaro Hara

     

    Development of protocols to quantify the twinning stress of a CoCrFeMnNi high entropy alloy108, Camila Aguiar Teixeira, Subin Lee, and Christoph Kirchlechner

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    Development of scalable downstream processing platform for HEK293SF cell-based influenza vaccine production, Amine Kamen, Xingge Xu, Zeyu Yang, Irene González Domínguez, Cécile Toussaint, Alice Bernier, Alina Venereo Sanchez, Omar Famos, and Cristina Aglaia Alves Tottoli e Silva

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    Development of the filamentous fungus Myceliophthora thermophila C1 into a next-generation therapeutic protein production system, Andriy Kovalchuk

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    Development of the filamentous fungus Thermothelomyces heterothallica C1 into a next-generation production platform for human and animal vaccines, Ronen Tchelet, Marika Vitikainen, Noelia Valbuena, Anne Huuskonen, Abraham Nyska, Markku Saloheimo, and Mark Emalfarb

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    Development of the Oxford AstaZeneca Covid Vaccine, Sarah Gilbert

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    Development of the PAT toolkit for continuous bioprocessing, Tiziano Brogna, Jean-Marc Bielser, Arnaud Perilleux, and Tiziano Brogna

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    Development of two monovalent antivenoms against two Moroccan viper venoms– daboia Mauritanica and Cerastes Cerastes, Naoual Oukkache, José Marcelino, and Abderrahmane Maaroufi

     

    Diagnostics for improved understanding of test environment and material interactions to advance oxidation-degradation models of UHTCs, Michael K. Cinibulk, Samuel Frueh, and Pavel Mogilevsky

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    Differential glycosylation and extracellular vesicle biogenesis in HEK293 upon transient transfection, Jesús Lavado-García, Irene González-Domínguez, Laura Cervera, Inmaculada Jorge, Jesús Vázquez, Tao Zhang, Manfred Wuhrer, and Francesc Gòdia

     

    Diffusional and microstructural profiles in metallic-to-UHTC conversion by carbonization, Haas Blacksher, Christopher R. Weinberger, and Gregory B. Thompson

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    Diffusion, disorder and dynamics in the nuclear pore complex, Roderick Lim

     

    Digital path to Industry 4.0: The role of data sciences in the cell & gene therapy space, Marc-Olivier Baradez

     

    Directed evolution of an efficient and thermostable PET depolymerase, Elizabeth Bell

     

    Directed evolution of novel AAV vectors for clinical gene therapy, David V. Schaffer

     

    Direct ink writing of ultra-high temperature ceramics, Swetha Chandrasekaran, Amy Wat, Wyatt Du Frane, James T. Cahill, Joshua Kuntz, Marcus A. Worsley, and Qi Rong Yang

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    Discovery & Development of Therapeutic Interfering Particles (TIPs): single-administration SARS-CoV-2 and HIV antivirals with high barriers to the evolution of resistance, Leor Weinberg

     

    discovery of CDX-6512, a gastrointestinal-stable methionine-gamma-lyase as a potential orally-administered enzyme therapy for homocystinuria, Leann Teadt

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    Disease X development and 100 days initiative, Nicolas Havelange

     

    Dislocation and grain boundary interaction in oxides: Slip transmission or cracking?, Kuan Ding, Enrico Bruder, Jürgen Rödel, Xufei Fang, Karsten Durst, Wolfgang Rheinheimer, and Atsutomo Nakamura

     

    Dislocation-based competition of plasticity and cracking in oxides: Understanding and application, Xufei Fang, Hanna Bishara, James Best, Gerhard Dehm, Kuan Ding, Till Fromling, and Karsten Durs

     

    Disruptive technologies for cell therapy manufacturing, Jen Moody

     

    Dissolved oxygen control in intensified perfusion bioreactors at benchtop and pilot scale, Ethan Penner, Jeffrey Swana, Daryl Powers, and Charles Budde

     

    Do more with less: Fit-for-purpose tools to speed up upstream process development for continuous biomanufacturing, Channing McLaurin, Quang Long Pham, and Jana Mahadevan

     

    Downstream Improvement for Recombinant Adeno-Associated Viruses (rAAV) Produced in iCELLis Nano 4 m2 Adherent Bioreactor, Paromita Majumder, Shannon Young, Paul Cashen, Mark Duncombe, John Welsh, and Kalliopi Zourna

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    Driving change in dtap batch release testing, Isabelle Bekeredjian-Ding, Bärbel Friedrichs, Walter Matheis, Björn Becker, Christel Kamp, Olga Ticha, and Volker Öppling

     

    Driving innovation in sustainability through product Life Cycle Assessments, Nicole Hunter and Christian Jermyn

     

    Dynamic process control of continuous twin-column chromatography, Giulio Lievore, Lars Aumann, Thomas Müller-Späth, Richard Weldon, and Sebastian Vogg

     

    Dynamics of Stocks and Flows in a Regenerative Economy, Roland Clift, Piero Salatino, and Roberto Chirone

     

    EBC Development and Behaviour Analysis for High Temperature CMC Components, Lisa Pin and Simon Arnal

     

    Economic and environmental assessment of lithium-ion battery recycling processes for electric vehicles, Giovanni De Feo

     

    Economic and environmental assessment of lithium‐ion battery recycling processes for electric vehicles, Giovanni De Feo, Rosario Tolomeo, and Libero Sesti Osséo

     

    Economic evaluation of externalities in waste management LCC studies: state‐of‐art, perspective and open issues, Antonio Massarutto

     

    Effect of hydrogen on the nanomechanical behavior of dual-phase nanocrystalline high-entropy alloy, Zhe Gao, Yakai Zhao, Hyun Jeon, Upadrasta Ramamurty, and Jae-il Jang

     

    Effects of EB-PVD microstrural features on CMAS infiltration of Yttria-rich zirconia coatings, Juan Gomez, Ravisankar Naraparaju, Ramana V. Chintalapalle, and Uwe Schulz

     

    Effects of radiation damage on the critical resolved shear stresses in zirconium alloys for nuclear applications, James Gibson; Chris Grovenor; and Angus Wilkinson,

     

    Efficient enzyme discovery from complex environmental microbiota using microbial single-cell sequencing, Soichiro Tsuda, Takuya Yoda, Keigo Ide, and Masahito Hosokawa

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    E-FLOAT: Extractable floating liquid gel-based organ-on-a-chip for airway tissue modeling under airflow, Siwan Park and Edmond W. K. Young

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    Elastomeric droplet generation of vascularized cardiac spheroids for the use of high-throughput drugs screening, Jennifer Kieda, Rick Lu, Yimu Zhao, Milica Radisic, and Shira Landau

     

    Electron beam induced softening of fused silica, Sebastian Bruns, C. Minnert, L. Petho, J. Michler, and K. Durst

     

    Electroporative Nano-Structures for Centrifuge-free and Efficient Immune T-cell Transfection, Andy Kah Ping Tay

     

    Emerging coating materials for H2 powered turbines, Molly O'Connor

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    Enablement by single-use technology of production of two billion vaccine doses of adenovirus-vectored vaccine in under a year, Carina Citra Dewi Joe, Jinlin A Jiang, Richard Turner, Thomas Linke, and Alexander D. Douglas

     

    Enabling AAV production by transient transfection with high cell density perfusion process, Ye Zhang, Emil Sundäng, and Veronique Chotteau

     

    Enabling PAT in insect cell bioprocesses: A monitoring toolbox for rAAV production, Inês A. Isidro, Daniel AM Pais, Rui MC Portela, Anastasiya Kryzhanska, Paulo Galrão, Manuel JT Carrondo, and Paula M Alves

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    Enabling technologies for manufacturing thermostable and cost-effective vaccines, Justin Stanbro, Akhilesh Bhambhani, Morrisa Jones, Donna Williams, Jeffrey T. Blue, and Tarit Mukhopadhyay

     

    Engineering a C4 fructose epimerase for production of tagatose, Kyle Roberts, Chris Dunckley, George McArthur, Suzanne Ma, Daniela Grabs, Bryan Julien, Sean Sleight, Becci Danford, Amber Olander, Mark Nance, Indroneil Ghosh, James Leinas, Josh Rhea, Deron Coffie, Michael Cockrem, and Alexandre Zanghellini

     

    Engineering characterisation of a cubic single-use bioreactor geometry, Jordan Delbridge, Timothy Barrett, Andrea Ducci, and Martina Micheletti

     

    Engineering enzymes for green manufacturing of noncanonical amino acids, David Romney

     

    Engineering enzymes for microbial control: Cell-free methods for enhancing antimicrobial efficacy through directed evolution, Erika Milczek, Will Shindel, Sampada Kalan, Robert DiCosimo, and Kamil Gedeon

     

    Engineering enzymes to produce high purity synthetic DNA, Anders Knight, Matt Miller, Jonathan Vroom, Charlene Ching, Rachelle Copeland, Stephanie Forget, Mikayla Krawczyk, Niusha Mahmoodi, Melissa Mayo, James Nguyen, and Amanda Tan

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    Engineering microbes and biology for communicating with electronics, William Bentley and Robert E. Fischell

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    Engineering Microbial systems: potential to enable affordable and accessible interventions for global health, Stephen Hadley

     

    Engineering of a redox neutral enzyme cascade for production of aliphatic diamines, Hannah Valentino and Joshua Michener

     

    Engineering of a redox neutral enzyme cascade for production of aliphatic diamines, Hannah Valentino and Joshua Michener

     

    Engineering of styrene oxide isomerase for enhanced production of (S)-2- arylpropionaldehydes, Joel Choo Ping Syong

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    Engineering Pichia pastoris to make the impossible hamburger possible, Smita Shankar

     

    Engineering proteins with 3D convolutional neural networks, Daniel Diaz

     

    Engineering substrates of transglutaminase using the Glutamine-Walk Strategy for specific modification of IgG1 antibodies, Joelle Pelletier, Adem Hadjabdelhafid-Parisien, Lukas Deweid, Arturo Maccaron, Sebastian Bitsch, Kiana Lafontaine, and Harald Kolmar

     

    Enhanced process control of an integrated and scalable bioprocess for production and isolation of MSC-derived extracellular vesicles for cardiac repair, Marta Costa, Inês Carrondo, and Enrique Oltra

     

    Enhancements for a more reliable single-use pH sensor, Stefan Bardeck

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    Enhancing production of the malaria asexual blood-stage vaccine candidate PfRipr5 in insect cells by modulating expression vector and culture temperature, Ricardo Correia, Eizo Takashima, Takafumi Tsuboi, Akihisa Fukushima, Sophie Houard, Manuel Carrondo, and António Roldão

     

    Enhancing rAAV production by HEK293 cells via metabolic profiling, Michela Pulix, Vera Lukashchuk, George Prout, Suzanne Podmore, Kevin Bowes, Daniel Smith, and Alan James Dickson

     

    Environmental and economic analysis to evaluate the valorization process of metallurgical waste and by-products, Andrea Di Maria, Giovanna Sauve, Mikel Merchán, Muriel Marchand, David Eguizabal, Maider García De Cortázar, and Karel Van Acker

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    Environmental and economic analysis to evaluate the valorization process of metallurgical waste and by‐products, Giovanna Sauve, Mikel Merchán, Muriel Marchand, David Eguizabal, Maider García De Cortázar, and Karel Van Acker

     

    Environmental and economic sustainability of agricultural waste collection and valorization, Giuseppe Vignali and Roberta Stefanini

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    Environmental aspects of the implementation of MSWI fly ash treatment methods in the Czech Republic, Monika Vitvarova, Ekaterina Korotenko, Vladimir Koci, and Michal Syc

     

    Environmental assessment framework for bio-based methane production via anaerobic digestion, gasification, and gas upgrading, Concetta Lodato, Lorie Hamelinb, Davide Tonini, and Thomas Fruergaard Astrup

     

    Environmental assessment framework for bio‐based methane production via anaerobic digestion, gasification, and gas upgrading, Concetta Lodato, Lorie Hamelinb, Davide Tonini, and Thomas Fruergaard Astrup

     

    Environmental assessment of different integrated biorefinery scenarios using walnut shells as a source for lignin production, Beatriz Santiago, Nezly Martelo Smalbach, María González Alriols, Gumersindo Feijoo, Jalel Labidi, and Sara González-García

     

    Environmental barrier coatings deposited by suspension plasma spraying, Dapeng Zhou and Robert Vaßen

     

    Environmental conical nozzle levitator equipped with dual lasers, Fox Thorpe, Elizabeth Sobalvarro Converse, Gabriella King, James Cahill, Joshua Kuntz, Wyatt Du Frane, and Scott J. McCormack

     

    Environmental reliability and crack propagation resistance of 3d-printed ALD-coated nano-ceramics, Marco Sebastiani, Edoardo Rossi, and Jens Bauer

     

    Environmental Sustainability of Municipal Waste Thermochemical Conversion Technologies, Lidia Lombardi and Susan Thorneloe

     

    Enzyme engineering for metabolic engineering, Kristala L.J. Prather

     

    EnzymeMiner: Exploration of sequence space of enzymes, Zbynek Prokop, Jiri Hon J, Simeon Borko, Jan Stourac, Jaroslav Zendulka, Tomas Martinek, Jiri Damborsky, and David Bednar

     

    Erbi Biosystems - Cell culture development with a 2 mL continuous perfusion bioreactor, Kevin Lee, Wei-Xiang Sin, Harry Lee, and Michael Birnbaum

     

    Establishing a highly automated and digitalized end-to-end bioprocess, Martin Purtscher, Manuel Dallinger, David B Nickel, Katerina Petrushevska-Seebach, and Stefan Romeder-Finger

     

    E Understanding the Stability of Mixed-Anion Deposits and Effects on Reactions with Advanced Coating Materials, David Poerschke, Eeshani Godbole, and Atharva Chikhalikar

     

    Evaluating by LCA the environmental impact savings related to the use of waste incineration bottom ash in porcelain tiles manufacturing: The role of metals recovery, Giulia Costa, Luigi Acampora, Luciano Piacenti, and Francesco Lombardi

     

    Evaluating carbon balance of wood cascading – the need for accounting storage period and rate of carbon uptake, Kranti Navare, Wouter Arts, Bert Sels, Giorgia Faraca, and Karel Van Acker

     

    Evaluating carbon balance of wood cascading – the need for accounting storage period and rate of carbon uptake, Kranti Navare, Wouter Arts, Bert Sels, Giorgia Faraca, and Karel Van Acker

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    Evaluation of a low-serum medium for growth and virus production with MRC-5 cells cultured on Cytodex 1 microcarriers, Michael Bruno, Haaris Huzair, and Anna-Barbara Hachmann

     

    Evaluation of sequence/activity relationships for more than 50 proteins: Implications for natural and directed evolution, protein engineering and machine learning algorithms, David Estell

     

    Evaluation of the cross-media effects of new emission limit values for waste-to- energy plants via a combination of process modelling and life cycle assessment, Alessandro Dal Pozzo, Samuele Abagnato, and Valerio Cozzani

     

    Evaluation of the cross‐media effects of new emission limit values for waste‐to‐energy plants via a combination of process modelling and life cycle assessment, Alessandro Dal Pozzo, Samuele Abagnato, and Valerio Cozzani

     

    Evaluation of the Environmental Feasibility of HTC Applied to the Organic Fraction Mechanically Separated From MSW, Lidia Lombardi, Francesca Tuci, Maciej Sliz, and Malgorzata Wilk

     

    Evidence of electron-irradiation activated creep in amorphous olivine at room temperature, Guillaume Kermouche, Andrey OREKHOV, Patrick CORDIER, and Michaël COULOMBIER

     

    Evolutionary-guided cofactor engineering, Paola Laurino

    PDF

    Expanding understanding and scope of Pichia pastoris for secreted protein expression, Nico Callewaert

     

    Experimental and numerical investigations of nanoindentation properties at the sub- grain level in Ni-based and Ti-based polycrystalline alloys, Damien Texier, Quentin Sirvin, Malo Jullien, Henry Proudhon, Samuel Forest, Vladislav Yastrebov, and Marc Legros

     

    Experimental techniques to study structure and thermodynamics at ultra- high temperatures, Sergey V. Ushakov, Alexandra Navrotsky, Xiao Xiao, and Juergen Brillo

     

    Exploring accurate structure, composition and mechanical properties of η carbides in high tungsten iron-based alloy: High-throughput mapping and DFT calculations, Yujie Meng, Xiaoyu Chong, and Warren Oliver

     

    Exploring constraints of sequence space in search of optimal enzymes, Sridhar Govindarajan and Claes Gustafsson

     

    Exploring different medium exchange regimes in ultra scale-down models, Marie Dorn, Kerensa Klottrup-Rees, Kenneth Lee, and Martina Micheletti

     

    Expression of anti-apoptotic genes to enhance rAAV production, David C atalán-Tatjer, Saravana Kumar Ganesan, Lise Marie Grav, Ivan Martínez-Monge, and Lars Keld Nielsen

    PDF

    Extracellular vesicles as next-generation nanomaterials, Anika Nagelkreke

     

    Extra cellular vesicles separation and biophysical characterization, Alois Jungbauer, Patricia Aguilar, Viktoria Mayer, and Alexander Zollner

     

    Factors influencing the performance of zirconia based thermal barrier coatings, Robert Vaβen, Jana Joeris, Olivier Guillon, and Daniel Emil Mack

     

    Fast evolution of active and/or enantioselective enzymes with a microfluidic enzyme screening platform, Zhi Li

     

    Fast fabrication of micropillar arrays using a combination of laser and FIB for micromechanical compression tests, Fang Zhou, Timo Bernthaler, Tim Schubert, Renato Pero, Alemnis AG, and Nicholas Randall

     

    Fatigue behavior of gold thin films at elevated temperatures studied by bulge testing, Anna Krapf, Megan Cordill, David Gebhardt, and Benoit Merle

     

    FDA’s progress in advanced manufacturing, Larry Lee

     

    Feedback control of particle morphology enables continuous monoclonal antibody capture via precipitation, Matthew Mergy, Sambit Ghosh, Mirko J. Minervini, Todd M. Przybycien, Andrew L. Zydney, Steven M. Cramer, and B. Wayne Bequette

    PDF

    Fermented pheromones – a sustainable solution for plant protection from insect pests, Irina Borodina

     

    Finite difference simulation ofphasetransformation kinetics in transition metal carbide composites, John Carter Stotts, Michael Large, Chris Weinberger, and Gregory Thompson

     

    FireProt ASR: Automated design of ancestral proteins, Zbynek Prokop, Milos Musil, Rayyan Tariq Khan, Andy Beier, Jan Stourac, Jiri Damborsky, and David Bednar

     

    First-principles prediction of thermal conductivity of zirconium carbide and hafnium carbide at ultra-high temperatures, Tianli Feng and Janak Tiwari

    PDF

    Flo8 – A versatile regulator for improving recombinant protein production in Pichia pastoris, Brigitte Gasser, Corinna Rebnegger, Diethard Mattanovich, Viktoria Kowarz, and Mirelle Flores

     

    Flotation of apatite and REEs as co-products from a Vietnamese sedimentary phosphate ore rich in carbonate and finely intergrowth, Huu Duong HOANG, Lucas Pereira, and Martin Rudolph

    PDF

    Flotation processing of Elandsfontein sedimentary phosphate ore from South Africa, Getrude Marape, Morake Hlahane, and Ashma Singh

     

    Fluid dynamics in a novel single-use bioreactor for personalised T-cell therapies, Gergana Georgieva Atanasova, Andrea Ducci, and Martina Micheletti

    PDF

    Fluorinated nanomaterials as powerful bioimaging tools in medicine, Francesca Baldelli Bombelli

     

    Foaming and Defoaming of the Wet Process Phosphoric Acid, Guoxin Wang and Guoxin Wang

     

    Forestry Waste in British Columbia - overcoming bad habits and perverse life cycle accounting, Roland Clift, Haoqi Wang, and Xiaotao . Bi

     

    Forestry Waste in British Columbia ‐ overcoming bad habits and perverse life cycle accounting, Roland Clift, Haoqi Wang, and Xiaotao Bi

     

    Fracture behaviour of Ti/TiN multilayer thin film modeling and experimental validation, Ashwini Kumar Mishra, Hariprasad Gopalan, Marcus Hans, Christoph Kirchlechner, Jochen M. Schneider, Gerhard Dehm, and Balila Nagamani Jaya

     

    Fracture propagation in glassy polymers: From nanometer to centimeter, Bruno Bresson, Matteo Ciccotti, Matthieu George, Yannick Nziakou, Guillaume Fischer, Caroline Genix, Stéphane Roux, and Jean-Louis Halary

     

    Fracture properties of CrN hard coatings: Influence of the microstructure, alloying elements, and coating architecture, Rainer Hahn, Stefan Rosenecker, Dominik Forstner, Tomasz Wojcik, Oliver Hunold, Szilard Kolozsvari, Paul H. Mayrhofer, and Helmut Riedl

    PDF

    From flask to large scale high cell density production of ω-transaminase using auto- induction media, Sofia Nunes, Mario A. Torres-Acosta, Sarah Slack, and Andrea Rayat

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    From genome to structure and beyond, Mariagrazia Pizza

     

    From lab coats to hard hats: Implementation of GMP continuous manufacturing on the road to commercial readiness, Mark Brower, Lara Fernandez-Cerezo, Nuno Pinto, and William Rayfield

     

    From microlattices to 3d microprinting of multiphase micro-components: Resolution limits and mechanical properties under extreme conditions, Johann Michler, Jakob Schwiedrzik, Manish Jain, Rajaprakash Ramachandramoorthy, Szilvia Kalacska, and Alexander Groetsch

     

    From N-1 to purified product in a closed and connected single use technology process industry, Andreas Castan and Helena Öhrvik

     

    From the atomic scale to the bulk: Ultra high temperature evaluation of metal diborides MB2 (M = Ta, Ti, Hf, Zr, Nb), Elizabeth Sobalvarro Converse, Fox Thorpe, Jesus Rivera, James Cahill, Gabriella King, Scott J. McCormack, Wyatt Du Frane, and Josh Kuntz

     

    Full-field strain around propagating shear bands and von mises criteria for metallic glasses, Olexsandr Glushko, Christian Mitterer, and Jürgen Eckert

     

    Fully automated on demand cell culture media preparation for perfusion bioreactors, Lisa Wolowczyk, Christian Schultheiss, and Jochen Sieck

    PDF

    Fungal highways enable migration and communication of engineered bacteria in soil, Eric Young, Nilesh Sharma, Felipe Carrillo, Jaclyn Thompson, Allison Taggart, Jacob Beal, Miles Rogers, and Natalie Farny

     

    Future engine challenges for TBCs/EBCs, Frank Preli

     

    Galectin-Anchored indoleamine 2,3-dioxygenase tissue-targeted therapeutic enzyme suppresses local inflammation in multiple animal models, Benjamin Keselowsky, Gregory Hudalla, Shannon Wallet, Craig Duvall, Kyle Allen, Ali Zarrinpar, and Dorina Avram

    PDF

    Generation of an international standard serum to measure influenza virus hemagglutinin stalk-reactive antibodies, Juan Manuel Carreno Quiroz, Tara Hurst, Raffael Nachbagauer, Mohammad Amin Behzadi, Shirin Strohmeier, Lynda Coughlan, Othmar Engelhardt, and Florian Krammer

    PDF

    Genetically detoxified diphtheria and tetanus toxins, EcoCRM197® and 8MTT, expressed in an engineered E. coli strain and use as conjugate vaccine carrier proteins, Andrew Lees, Morgane Ollivault-Shiflett, Min-Ju Chang, and Renaud Jacquemart

    PDF

    Genetically encoded biosensors as tools for the up-cycling of aromatic-based feedstocks, Guadalupe Alvarez Gonzalez and Neil Dixon

    PDF

    Genetically stable CRISPR-based kill switches for engineered microbes, Tae Seok Moon, Austin G. Rottinghaus, Aura Ferreiro, Skye R.S. Fishbein, and Gautam Dantas

    PDF

    Genomics of Vero cells: Understanding this cell line and its virus-host interactions for improved vaccine production, Marie-Angelique Sene,; Sascha Kiesslich; Haig Djambazian; Ioannis Ragoussis; Yu Xia; and Amine A. Kamen

     

    GENOSCALER™: A Next-Generation high throughput enzyme, pathway, and genome engineering platform, Richard Fox

     

    GMP implementation of continuous manufacturing: A case study, Neil Soice

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    Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris, Jennifer Staudacher, Corinna Rebnegger, Diethard Mattanovich, and Brigitte Gasser

     

    Grain size tailoring of tungsten copper nanocomposites to affect local fracture characteristics, Klemens Schmuck, Markus Alfreider, Michael Burtscher, Michael Wurmshuber, and Daniel Kiener

    PDF

    Growth-decoupled recombinant protein production in Escherichia coli, Patrick Stargardt, Lukas Feuchtenhofer, Jürgen Mairhofer, Florian Weiss, and Gerald Striedner

     

    Growth through sustainable business model innovation using ICIS Framework, Chor Sing Tan, Brian Ho, Lacy Linney, Christian Anderson, and Karin Daar

    PDF

    Heart-on-a-chip Platform to Model Cardiac Sars-cov-2 Pathogenesis and Therapeutic Screening, Stefaan De Smedt

     

    Helix engineering: Combining the power of 3DM with AI to disrupt protein engineering, Stephan Heijl, Jeanine Boot, Tom van den Bergh, Bas Vroling, Henk-Jan Joosten, and Bastiaan Brier

    PDF

    Hidden methanol assimilation pathways in the methylotrophic yeast Pichia pastoris, Bernd Mitic, Christina Troyer, Stephan Hann, Diethard Mattanovich, and Tim Causon

     

    High-cell density cryopreservation strategy, Julien Muzard, Jonathan Cartoux, and Muhammad Siddiqui

    PDF

    High cell density culture for VLP production in latent virus-free insect cell line, Lena Achleitner, Peter Satzer, and Alois Jungbauer

    PDF

    High Density HEK293T culture for high yield, high quality, stable adenoviral vector production in Ambr® 250 stirred tank reactors, Amélie Boulais, Lara Nascimento-Brooks, Shuangqing Yu, Zhicheng Cao, Li Hu, Shuren Feng, Jinlu Du, Cuiling Song, and Junjie Luo

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    High Entropy Rare Earth A2b2o7 Type Zirconates, Daniel R. Lowry, Sean Bishop, Stephen Meserole, Mark Rodriguez, Eric Coker, and Khalid Hattar

     

    High Entropy Rare Earth Oxide (HERO) Environmental Barrier Coatings for Refractory Metal Alloys, Elizabeth Opila, Prasanna Balachandran, Bi-Cheng Zhou, Patrick Hopkins, Carolina Tallon, and Jonathan Laurer

     

    Highly automated bioburden-free continuous manufacturing biologics GMP operations: How to get there?, Lara Fernandez Cerezo, Matthew Serota, Emil Rosenkrantz, Fadlan Saiti, Cyrill Stadelmann, Pius Emmenegger, Andrea Eichenberger, Alex Hoffmann, Tobias Zumbuehl, Susan Brunner, Parinaz Emami, Mihai Buciu, Ivan Krizanovic, Akos Ferenczi, Alexandra David, Adrian Gospodarek, Nuno Pinto, Frankie Pelaez, Will Rayfield, Silvia Sonjak, Scott Hooper, Stefan Weber, Mark Brower, and Matt Kessler

     

    Highly Stable Nanolamellar MXene-derived Carbides by Phase Transformation of Ti3C2Tx and Mo2TiC2Tx MXenes, Babak Anasori, Brian C. Wyatt, S. Kartik Nemani, and Wyatt Highland

     

    High resolution single cell profiling of human hematopoietic stem cell drug products, Luca Biasco

     

    High strain rates micromechanical behavior of materials: A coupled experimental and numerical approach, Benedicte Adogou, Marc Fivel, Gaylord Guillonneau, Sergio Sao-Joao, and Guillaume Kermouche

     

    High strain rate testing of ultra fine grained aluminium at micro and macro length scales112, Aloshious Lambai, Jari Kokkonen, Mikko Hokka, Veli-Tapani Kuokkala, and Gaurav Mohanty

     

    High Temperature Refractory Metal Alloys-advances and Challenges, John Perepezko

     

    High-temperature scanning indentation: A new technique to assess microstrutural changes along thermal ramping, Gabrielle Tiphene, Paul Baral, Solène COMBY-DASSONNEVILLE, Gaylord GUILLONNEAU, Guillaume KERMOUCHE, Jean-Michel BERGHEAU, and Warren OLIVER

     

    High-throughput affinity-resin based scale down method for T cell isolation, Marielle Summers, Guy Caspary, Calvin Chan, Sabine Radisch, and Irina Treise

    PDF

    High-throughput enzyme engineering for commercial-scale production of natural products, Irina Koryakina, Yue Yang, Svetlana Borisova, William Draper, Wenzong Li, and Victoria Hsiao

     

    High-throughput enzyme engineering for commercial-scale production of natural products, Irina Koryakina, Yue Yang, Svetlana Borisova, William Draper, Wenzong Li, and Victoria Hsiao

    PDF

    High-throughput liver microenvironment engineering, Gregory Underhill

     

    hiPSC and hiPSC-cardiomyocytes are alternative EV biofactories for cardiac regeneration, Paula Marques Alves, Ana Filipa Louro, Marta Oliveira, Marta Abreu Paiva, Margarida Serra, and Patrícia Gomes-Alves

     

    How do H/E and H3/E2 control coating system wear? - Insights gained from elevated temperature nanoindentation, scratch and impact tests, Ben D. Beake

     

    Hybrid modeling approaches for autologous cell therapy process characterization, Mridul Dalmia

     

    Hydrogen induced hardening effect and the diffusion behavior in bcc Fe-Cr alloys by in situ nanoindentation, Maria Jazmin Duarte Correa, Subin Lee, Chun-Hung Wu, Binhan Sun, Michael Rohwerder, Gerhard Dehm, and María Jazmin Duarte

     

    Imaging modalities of mechanical microscopy, Jeffrey M. Wheeler

     

    Immobilized enzymes for green pharmaceutical applications, Fred Ghanem

    PDF

    Immune-profiling of innate and adaptive immunity following three vaccinations of the MERS vaccine candidate MVA-MERS-S, Christine Dahlke, Anahita Fathi, Leonie M. Weskamm, Bart L. Haagmans, Stephan Becker, Gerd Sutter, and Marylyn M. Addo

    PDF

    Immunogenicity and efficacy of non-adjuvant tissue culture-based rabies vaccine produced in Ethiopia, Birhanu Hurisa, A Mengesha, G Kebede, A Godana, A Adhanom, S Kerga, D Nigussie, H Lemma, A Kebede, B Newayesiliasie, G Gebrewold, D Bankovskiy, A Metlin, and K Urga

    PDF

    Impact of Africa-based manufacturing on cost-per-dose: A theoretical, inside-out analysis, Casey Selwyn

     

    Impact of intermediate volumes and cell diameters on cell recovery: A predictive model for autologous immunotherapy workflows, Craig Mizzoni, Alena Plotkin, Candace Rhodes, Ala Tobeh, Mojtaba Parvizi, and Rohin Iyer

    PDF

    Impact of oxygen availability on organelle-specific redox potentials and stress in recombinant protein producing Pichia pastoris, Aliki Kostopoulou, Corinna Rebnegger, Brigitte Gasser, and Diethard Mattanovich

    PDF

    Implementation of intensified and continuous processing to increase yield of lentivirus manufacturing, Keen Chung, Ly Truong, Riaj Mahamud, Philip Yuen, Mike Bransby, and René Gantier

     

    Implementation of PAT-based control strategy for continuous formulation, Sushmitha Krishnan, Shashi Malladi, Erin Holahan, Chad Varner, Michael Coolbaugh, Marina Hincapie, Jason Walther, and Kevin Brower

    PDF

    Implementing X-ray for single use systems sterilization, Samuel Dorey, Mélanie Gauthier, Isabelle Gay, Nina Girard-Perier, Fanny Gaston, Nathalie Dupuy, and Sylvain R.A Marque

    PDF

    Implications of the nuclear pore barrier for non-small cell lung cancer malignancy and therapy, Silvio Terra Stefanello, Isabelle Luchtefeld, Ivan Liashkovich, Ihab Azzam, Etmar Bulk, Gonzalo Rosso, Caren Rigon Mizdal, and Victor Shahin

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    Improved Ad26 vaccine stability by mitigating interaction of viral particles with glass surfaces, Martinus Capelle, Olga Labovitiadi, and Joao Calado da Silva Freire

     

    Improving bioreactor performance using mobile sensors, Jonas Bisgaard and Tue Rasmussen

     

    Improving the Representation of Solid Waste Management in the Ecoinvent Database, Avraam Symeonidis and Emilia Moreno Ruiz

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    Increasing of PK15 biomass for PCV viral antigen production using modelbased and media optimization strategies that consider cellular metabolic requirements, Ziomara Gerdtzen, Felipe Véliz, Gerardo Flores, Felipe Sánchez, Andrea Villanueva, Kurt Pohlhammer, Daniel Morales, J. Cristian Salgado, Iván Valdés, Harold Oliva, and Samuel Valdevenito

    PDF

    Increasing the carbon efficiency of citric acid production, Evelyn Carolina Vásquez Castro, Özge Ata, Michael Sauer, Matthias G.. Steiger, and Diethard Mattanovich

    PDF

    Indentation unloading phase transformations in silicon: A new perspective, Gerald J osef Kamillo Schaffar, Daniel Tscharnuter, and Verena Maier-Kiener

     

    Indicators for selecting between alternatives in comparative LCA of waste management systems, Valentina Bisinella

     

    Induced pluripotent stem cells for candidate cell line selection of off-the-shelf natural killer cell therapy, Jason Mills, Chen-Yuan Kao, Matthew O’Rourke, Barry Morse, Bruno Marques, and Greg Russotti

     

    Industrialization of the GMP manufacture of exosome therapeutics and opportunities for further multifold process productivity increase, Konstantin Konstantinov

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    Industry perspective on the future of organ-on-chip applications, Thomas Neuman

     

    Influence of alumina addition on steam corrosion behaviour of Ytterbium disilicates for EBC applications, Ahmet Hilmi Paksoy, João P. Martins, Huatang Cao, Ping Xiao, Ying Chen, and Grant Gibson

    PDF

    Influence of DNA-protein interactions on purification and assembly of virus-like particles, Lukas Gerstweiler,; Jingxiu Bi; Linda Lua; and Anton Middelberg

     

    Influence of Nb coating on the oxidation behavior of ZrB2, Jan Erik Förster, Ravisankar Naraparaju, William G. Fahrenholtz, and Gregory E. Hilmas

    PDF

    Influenza A virus-derived defective interfering particles for antiviral treatment, Sascha Y. Kupke, M D. Hein, Y Genzel, L Pelz, P Marichal-Gallardo, N Bdeir, S Pöhlmann, U Rand, L Cicin-Sain, F Alnaji, C Brooke, M Winkler, L Cicin-Sain, D Bruder, K Schughart, and U Reichl

     

    In-line monitoring and control of glucose concentration with single-use sensors in CHO and stem cell applications, Jan Müller, Valentin Jossen, Regine Eibl, and Dieter Eibl

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    Innovative facility options in a new era of urgent capacity needs, Thomas Hauser

     

    Innovative Gravity Separation for Sustainable Utilization of Mineral Resources, James Mennie, Patrick Zhang, and Aaron Medley

     

    Insights from applying different assessment methods for metals resource use, Maria Ljunggren Söderman

     

    Insilico guided CRISPR-Cas driven enzyme engineering framework: An automated and efficient enzyme engineering method, Anuj Shetty, Pravin Kumar, Khantika Patel, Roopa L, Gladstone Sigamani, and Dipa Natarajan

     

    In silico screening of transaminase using semi-empirical QM/MM approach, Marc Hayes, Haibin Chen, Shuai Huang, Junpeng Xu, Marco Bocola, and Xiao-Lei Wang

     

    In silico screening of transaminase using semi-empirical QM/MM approach, Marc Hayes; Shuai Huang; Junpeng Xu,; Marco Bocola; and Xiao-Lei Wang

     

    In situ 3D mapping of local stress and crystal defect structures during micro-mechanical testing by n3D-XRD-CT, Thomas Edwards, Xavier Maeder, Szilvia Kalacska, Nicolo Maria Della Ventura, Jon Wright, and Johann Michler

     

    In situ deformation observation via EBSD and EDS during high temperature tensile testing, Sebastian Krauss, Markus Boese, Benjamin Tordoff, and Hrishikesh Bale

     

    In-situ high temperature spatially resolved X-ray diffraction of TiB2 up to ~3250 ˚C, Scott McCormack, Fox Thorpe, Elizabeth Sobalvarro Converse, Joshua Kuntz, Wyatt Du Frane, and Gabriella King

     

    In-situ micromechanical testing of Su-8 polymer at high strain rates using indentation and micropillar compression, Rahul Cherukuri, Aloshious Lambai, Lassi Sukki, Pasi Kallio, and Gaurav Mohanty

     

    In situ micromechanics during hydrogen charging: Effect of diffusible hydrogen on BBC Fe-based alloys and hydrogen protection through hydrogen barrier coatings, Maria Jazmin Duarte Correa, Jing Rao, Hariprasad Gopalan, Piyush Patil, Christina Scheu, and Gerhard Dehm

     

    In-situ monitoring of the contact area during indentation creep testing, Ude Hangen and Douglas Stauffer

     

    In-situ nanomechanical testing at elevated humidities, Igor Zlotnikov

     

    Integrated & continuous processing: A proven solution to tackle gene therapy manufacturing challenges, Rimenys Carvalho and Tania Pereira Chilima

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    Integrated end-to-end MVA viral vector production: Perfusion culture shows economical advantage over batch culture, Gwendal Gränicher, Pavel Marichal-Gallardo, Sven Göbel, Masoud Babakhani, Ingo Jordan, Volker Sandig, Yvonne Genzel, and Udo Reichl

     

    Integrated intracellular organization and reorganization of the human stem cell, Susanne Rafelski

     

    Integrated self-healing thermal protection for high-speed vehicles, Steven Storck, Dajie Zhang, Daniel Eby, Matthew Shanaman, and Steven Storck

     

    Integrated upstream and midstream processing with scalable pre- configurated single-use assemblies for accelerated commercial reach, Thomas Robert

     

    Integrated upstream and midstream processing with scalable pre-configurated single- use assemblies for accelerated commercial reach, Tania Pereira Chilima

     

    Integration of low-pH viral inactivation and primary clarification processes in a single use disposable biosettle, Dhinakar Kompala and Christopher Glascock

    PDF

    Intensification of influenza virus production in fed-batch and perfusion cultures of HEK293SF cells, Cristina A.T. Silva, Amine A. Kamen, and Olivier Henry

     

    Intensification of viral vector production and clarification by integration of perfusion platforms, Rene Gantier, Rene Gantier, Michael Bransby, Earl Pineda, Joao Mendes, Ricardo Silva, Cristina Peixoto, and Antonio Roldao

     

    Intensified bioprocessing: Data, data, everywhere..., Marc Bisschops, Mark Schofield, Keith Gillette, Christina Caporale, and Terése Joseph

     

    Intensified bioprocessing enabling single-use technologies, Martin Glenz and Marc Bisschops

     

    Intensified & connected processing for fast, cost effective, and robust monoclonal antibody, Sanket Jadhav, Abijar Bhori, Priyanka Gupta, and Himanshu Gadgil

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    Intensified high yield production of GMMA based vaccines for high burden neglected disease, Luigi Sollai, Angela Daniele, Giulia Iannello, Federico Pippi, Antonia De Felice, Francesca Necchi, Rocio Cannals, Francesco Berlanda Scorza, and Anna Maria Colucci

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    Interstitial photothermal therapy generates durable treatment responses in neuroblastoma, Debbie Ledezma, Preethi B. Balakrishnan, Jacob Medina, Allan Bowen, Anshi Shukla, Emily Oakley, Gal Shafirstein, Mario Miscuglio, and Rohan Fernandes

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    Intranasal administration of NDV-HXP-S COVID19 vaccines induces robust protective mucosal and systemic immunity in mice, Stefan Slamanig, Weina Sun, Irene Gonzalez, Nicholas Lemus, and Peter Palese

     

    Intrinsic room temperature ductilisation of lean rare-earth free ternary Mg alloys, Wassilios Johannes Delis, Pia C. Huckfeldt, Bengt Hallstedt, Pei-Ling Sun, Dierk Raabe, Sandra Korte-Kerzel, and Stefanie Sandlöbes-Haut

     

    Investigating adhesion of polyimide in semiconductor devices with cross-sectional nanoindentation, Moritz Hartleb, Peter Julian Imrich, and Johannes Zechner

     

    Investigating the microstructure of as-sprayed high-crystalline Yb2Si2O7 environmental barrier coating (EBC) deposited by atmospheric plasma spray (APS), Christian Moreau and Farzam Arhami

     

    Investigating the microstructure of as-sprayed high-crystalline Yb2Si2O7 environmental barrier coating (EBC) deposited by atmospheric plasma spray (APS), Christian Moreau and Farzam Arhami

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    Investigating the role of oxidative stress response genes in protein secretion using a novel combinatorial Golden Gate based approach, Victor Mendes Honorato, Jennifer Staudacher, and Brigitte Gasser

     

    Investigation of anomalous hardness in sub-stoichiometric transition metal carbides using ab-initio simulations, Brennan Watkins and Christopher R. Weinberger

     

    Investigation of the oxidation resistance of ZrB2-based monoliths using polymer-derived Si(Zr,B)CN as sintering aid, Nils-Christian Petry, Anke Silvia Ulrich, Bo Feng, Emanuel Ionescu, Mathias Christian Galetz, and Maren Lepple

     

    Isolation of acellular derivatives of human amniotic fluid in single-use implementation, Mikhail Skliar

     

    Journey to commercialization of a complex, biological ancillary material, Lili Belcastro, Norbert Hentschel, and Takeshi Nishiura

     

    Ketoreductase immobilization for batch and flow processes, Fred Ghanem

     

    Key drug product considerations for iPSC-derived NK cell therapies, Lavanya Peddada

     

    Key enablers of continuous manufacturing success through a flexible J.POD® platform, Eva Gefroh

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    Klebsiella pneumoniae as cell factory for chemicals production, Frank Baganz, Jian Hao, and Gary Lye

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    Lactic acid production in the synthetic autotroph Komagataella phaffii, Michael Baumschabl, Thomas Gaßler, Özge Ata, and Diethard Mattanovich

     

    Laser additive manufacturing of ultra high temperature ceramics, Steven Storck, Joseph Sopcisak, Hyun Jun Kim, Derek King, Carmen Carney, Collin McClain, and Morgan Trexler

    PDF

    Late stage process development for a commercial streptococcus pneumoniae fermentation bioprocess, Matthew Woodling, Christopher Lee, and Jon Shanter

     

    LCA-Assisted Conception of a Digestate Recovery by Micro-Algae Production, Jean-Romain Bautista Angeli, Marilys Pradel, Fabrice Beline, and Lynda Aissani

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    LCA-assisted conception of a digestate recovery by micro-algae production, Jean-Romain Bautista Angeli, Marilys Pradel, Lynda Aissani, and Fabrice Beline

     

    LCA for emerging waste treatment technologies: theoretical approach and practical application, Christina Tsouti, Christina Papadaskalopoulou, Maria Lida Christou, Thomas Kotsopoulos, Petros Samaras, and Katerina Valta

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    LCA of food waste management in Italy, with a special focus on the effect of the bags used for the collection, Mario Grosso, Lucia Rigamonti, and Giovanni Dolci

     

    LCA of the improvement potential for construction and demolition waste: The role of site specificity and quality, Anders Damgaard and Ulf Smith Minke

     

    LCT as Lever to Overcome Barriers in Areas Suffering from NIMBY Syndrome: The Case Study of Campania Region in Southern Italy, Giovanni De Feo, Carmen Ferrara, and Alberto Grosso

     

    Learning from flexpack industry: Closing the loop, Jürgen Betz

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    Learnings from the development of Covid-19 vaccines, Kathrin Jansen

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    Lessons in vaccine process development, Tara Tagmyer

     

    Lessons learned in design and characterization of EBC spray powders, Ursa Pirnat, Richard Trache, and Karl Körner

     

    Leveraging microfluidics for linking protein sequence to function in high- throughput, Polly Fordyce

     

    Life cycle analysis of different biochar production processes for simultaneous waste management and carbon capture credits, Franco Berruti, Jodi Formosi, and Katie Soulliere

     

    Life Cycle Assessment of Alkali Activated Cement compared to Ordinary Portland Cement, Anna Alfocea‐Roig, A. Maldonado-Alameda, J. Giro-Paloma, J. Formosa, and J.M. Chimenos

     

    Life Cycle Assessment of Multi-Loop Recycling: Opportunities and Challenges, Gloria Moscatelli and Thomas Fruergaard Astrup

     

    Life cycle assessment of multi-loop recycling: Opportunities and Challenges, Gloria Moscatelli and Thomas Astrup

     

    Life Cycle Environmental Impact Assessment of Sludge Treatment Technologies Based on Uncertainty Analysis, Huimin Chang, Yan Zhao, Anders Damgaard, and Thomas H. Christensen

     

    Life cycle impacts of WEEE plastics recycling within the PLAST2bCLEANED project, Spela Ferjan, Anna Schwarz, and Toon van Harmelen

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    Liquid co-polymers as biodegradable surgical sealant, Neta Shimony, Alona Shagan, Boaz Mizrahi, Adi Gross, Bat-hen Eylon, and A. Nyska

     

    Localization of plastic strain in alloy 718 using digital image correlation, Malo Jullien and Marc Legros

     

    Local mechanical response in the vicinity of single grain boundary in YSZ measured by nanoindentation, Ryo Nakamura, Hiroshi Masuda, and Hidehiro Yoshida

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    Long-term propagation of influenza A virus and its defective interfering particles: Analyzing dynamic competition to select antiviral candidates, Lars Pelz, Daniel Rüdiger, Tanya Dogra, Fadi G. Alnaji, Yvonne Genzel, Christopher B. Brooke, Sascha Y. Kupke, and Udo Reichl

     

    Looking beyond the horizon: Exosomes at the vanguard of integrated continuous processing of bionanoparticles, Aaron Noyes

     

    Low Grade Igneous Phosphatic Rock Flotation Using Sorghum Starch as Depressor, Elenice M. S. Silva, Andre C Silva, Laura G Rasmussem, and Luis A Silva

     

    Low-toxity gelcasting to 3D shaping of UHTCs, Carolina Tallon and Julia N. Goyer

     

    Making better proteins: Learning from the best, Olga Khersonsky

     

    Manual visual inspection for particulates in single-use systems: Method development and validation, Klaus Wormuth, Olivier Benoit, Dany Laruelle, and Dounia Kateb

     

    Manufacturing of gene-modified human mesenchymal stromal cells in microcarriers and agitated conditions, Pedro Silva Couto, Dale Stibbs, and Qasim Rafiq

     

    Manufacturing of patient specific novel T cell therapies using the Cocoon® Platform automated system, Joseph O'Connor, Kalyani Daita, Janet Sei, Eytan Abraham, and Yaling Shi

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    Materials and devices for stretchable and self-healing bioelectronics, Fabio Cicoira

     

    Materials processing and property-structure characterization capabilities at The University of Alabama, Gregory Thompson and Christopher R. Weinberger

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    Maximizing viral titer yield at harvest through metabolic process analytical technology (PAT), Katherine Forrester, Marena Trauger, Thomas Randolph Blanda, and Neil Templeton

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    mDOE for development of optimized fed-batch cultivation for the production of PET degrading enzymes in E. coli, Lisa Fohler

     

    Measurement of hardness and elastic modulus by depth sensing indentation: Improvements to the technique based on continuous stiffness measurement, Warren C. Oliver, P. Sudharshan Phani, and G.M. Pharr

     

    Measuring Recycling and Recycled Content Benefits in LCA - Implications for Policy Design, Sofia Carvalho and António Lorena

     

    Measuring Recycling and Recycled Content Benefits in LCA ‐ Implications for Policy Design, Sofia Carvalho and António Lorena

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    Measuring the liquid volume in a flexible bioprocess container with Single Use Pressure Sensors, Nick Troise and James Furey

     

    MecaNano – European network for mechanics of matter at the nano-scale, Benoit Merle

     

    Mechanical andthermal properties of Zeta phase tantalum carbide atelevated temperatures, Evan Schwind, Greg E. Hilmas, and William G. Fahrenholtz

     

    Mechanical behavior of optimized optical nanomultilayers, Danielle White, Edoardo Rossi, Marco Sebastiani, and Andrea M. Hodge

     

    Mechanical behaviors of agglomerated ceramic powders for cold spraying applications, Sergio Sao Joao; Geoffrey Céleste; and Guillaume Kermouche, Séverine Girard

     

    Mechanical properties and deformation mechanisms of manganese sulphide inclusions, Maximilian A. Wollenweber, Carl F. Kusche, James S.K.-L. Gibson, and Sandra Korte-Kerzel

     

    Mechanical properties and fracture behavior of TiB2+z thin films, Anna Hirle, Christoph Fuger, Rainer Hahn, Philip Kutrowatz, Peter Polcik, Maximilian Weiss, Andreas Limbeck, Oliver Hunold, and Helmut Riedl

     

    Mechanical properties of Yb2Si2O7 coatings prepared using electrophoretic deposition, Esma Yilmaz, Ahmet Hilmi Paksoy, and Ping Xiao

     

    Mechanical properties of Yb2Si2O7 coatings prepared using electrophoretic deposition, Esma Yilmaz, Ahmet Hilmi Paksoy, and Ping Xiao

     

    Mechanics of elastic contact with an interface between adjacent materials, Kian Tadayon and Igor Zlotnikov

     

    Mechanistic modeling to predict titers and infected cells in the two-stage continuous production of a viral vaccine, Krystian Ganko; Moo Sun Hong; Sangmook Lee; Kaylee C. Schickel; Joules Provenzano; Anthony Grippe; James Wagner; Helen Achwei; David McNally; Stacy L. Springs; Paul W. Barone; and Richard D. Braatz,

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    Mechano-evolution and drug resistance in compact populations, Jona Kayser

     

    Memories of late professor Hideaki Yamada, a giant in enzyme engineering, and successive activities stemmed from his philosophy, Jun Ogawa and Sakayu Shimizu

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    Metabolic Engineering, Kristala L. J. Prather

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    Metabolic modeling for the microbiome, Costas Maranas, Debolina Sarkar, and Joshua Chan

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    Method development, validation, and implementation of Raman spectroscopy as an in-situ process analytical technology for fermentation process development and commercial manufacturing, Griffin Thomas, James O’Connor, Brian Marks, Matthew Woodling, and Jon Shanter

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    Microarray patch delivery of un-adjuvanted influenza vaccine induces potent and broad-spectrum immune responses in a phase I clinical trial, Alexandra C. I. Depelsenaire, Angus H. Forster, Katey Witham, Margaret Veitch, James W. Wells, Christopher D. Anderson, Adam Wheatley, Melinda Pryor, Jason D. Lickliter, Barbara Francis, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, and Germain J. P. Fernando

     

    Microbial Engineering II, Barry Buckland and Eli Keshavarz-Moore

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    Microbial engineering of new Streptomyces sp. from extreme environments for novel antibiotics, anticancer and antifungal Drugs, Juan Asenjo, Valeria . Razmilic, Diego Lagos, Scott Jarmusch, and Barbara Andrews

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    Microbial platform for vaccine production for low and medium income countries (LMICs): 2 case studies, Salome De Magalhaes, Almir Yamanie, Neni Nurainy, and Eli Keshavarz-Moore

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    Microbial platform for vaccine production for Low-and Medium-Income Countries (LMICs): 2 case studies, Salomé de Sá Magalhães, Stephen A. Morris, M. Lourdes Velez-Suberbie, Acep Riza Wijayadikusumah, Neni Nurainy, and Eli Keshavarz-Moore

     

    Microbiome product manufacture out of a SU facility set up, Christopher McChalicher and Dave Ege

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    Microfluidic spinning of topographical hollow fibers for the development of a 3D functional glomerulus in vitro, Chuan Liu, Anastasia Korolj, Chuan Liu, Rick Xing Ze Lu, Xin Song, Boyang Zhang, Arun Ramachandran, Qionglin Liang, and Milica Radisic

     

    Micro-mechanical approach of the intergranular stress corrosion cracking of austenitic stainless steels in PWR environment, Rachma Azihari, Jeremy Hure, Marc Legros, and Benoit Tanguy

     

    Micromechanical characterisation of protein crystals and filamentous microorganisms, Achim Overbeck, Marcel Schrader, Arno Kwade, Marta Kubiak, and Ingo Kampen

     

    Micromechanical study of a precipitation-hardened dual phase highentropy alloy, Szilvia Kalacska, Amit Sharma, Rajaprakash Ramachandramoorthy, Johann Michler, and Xavier Maeder

     

    Micromechanical Testing of Thermal Barrier Coatings, Ying Chen, Ping Xiao, and Gyaneshwara Brewster

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    Microphysiological models of neurological disease, Roger Dale Kamm

     

    Micropillar compression of anisotropic Al2O3-based eutectic composite, Yuta Aoki, Hiroshi Masuda, and Hidehiro Yoshida

     

    Micro-scale damage tolerance studies in ferroelectric barium titanate thin films, Nidhin George Mathews, Aloshious Lambai, Gaurav Mohanty, Christoph Kirchlechner, N Venkataramani, Gerhard Dehm, and Balila Nagamani Jaya

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    Microscale technologies to decode EV-mediated cell behavior, Elisa Cimetta

     

    Microshear mechanical properties measurements on tribolayers, Fadlallah Abouhadid, Guillaume Kermouche, Sergio Sao-Joao, and Gaylord Guillonneau

     

    Micro-shear of silicon: Elastic strain analysis using digital image correlation, Carmen Maria Lauener, Fabian Schwarz, Jeffrey M. Wheeler, Johann Michler, Ralph Spolenak, and Laszlo Pethö

     

    Microstructural and mechanical characterization of yarns made from carbon nanotubes for the instrumentation of particle beams at CERN, Ana Teresa Perez Fontenla, A. Mariet, R. Veness, X. Gabrion, M. Devel, C. Salomon, R. Pero, and N. Randall

     

    Microstructure and Phase Composition Evolution of Thermal Sprayed Yb- Silicate Coatings during Post Heat Treatment and Burner Rig Test, Emine Bakan, Daniel E. Mack, Robert Vaßen, and Dapeng Zhou

     

    Microstructure modification of EB-pvd gadolinium zirconate thermal barrier coatings and the effect on their resistance against siliceous CMAS melts, Christoph Mikulla, Ravisankar Naraparaju, Peter Mechnich, and Uwe Schulz

     

    Microstructure modification of EB-pvd gadolinium zirconate thermal barrier coatings and the effect on their resistance against siliceous CMAS melts, Christoph Mikulla, Ravisankar Naraparaju DLR, Peter Mechnich DLR, and Uwe Schulz DLR

     

    Microstructure, phase formation and cyclic behavior of PVD-based Y- silicate Environmental Barrier Coatings for SiC-SiC CMC, Uwe Schulz, Vito Leisner, and Ronja Anton

     

    Mineral liberation using selective fragmentation of phosphate ore, Lev O. Filippov, Rima Boucif, Inna V. Filippova, Fréderic Diot, Mustapha Maza, and Jérôme Marin

     

    Miniaturization effects on the tensile behavior of multicrystalline and polychristalline nickel-based superalloy: Influence of grain size, free surface and precipitation state, Damien Texier, Vincent Velay, Antonio Castro Moreno, Daniel Monceau, Daniel Hourcade, and Eric Andrieu

     

    Miniaturization of chromatographic process development: Achieving fast results with minimal costs, Tiago Castanheira Silva, Michel Eppink, and Marcel Ottens

     

    Mixing the transition metals in transition metal carbides, Christopher Weinberger, Xiaochuan Tang, Kaka Ma, and Gregory Thompson

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    Model assisted design of an intensified bioprocess, Ruth de la Fuente and Marc Bisschops

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    Model based control of continuous bioprocesse, Anurag Rathore

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    Model-based process development for complex vaccine mixtures, Daphne Keulen, Roxana Disela, Geoffroy Geldhof, Olivier Le Bussy, Martin Pabst, and Marcel Ottens

     

    Modeling environmental effects in MeB2/SiC UHTCs: Oxidation by oxygen and water vapor, Pavel Mogilevsky, Samuel Frueh, and Michael Cinibulk

     

    Modelling biocatalytic processes to accelerate enzyme and process development, John Woodley

     

    Monoclonal antibody purification from gram to kilogram scale utilizing multi-column continuous rProtein A capture, J. Kevin O'Donnell, William Wessel, and Anthony Grabski

     

    Moving adsorption belt system for continuous bioproduct recovery, Yijia Guo and Hector Marcelo Fernandez Lahore

     

    Multilayer TBCs and EBCs: Integrating Design and Manufacturing Innovations for Multifunctional Performance, Sanjay Sampath

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    Multimodal chromatography combining steric exclusion and cation exchange as an intermediate downstream step to purify yellow fever virus-like particles, Túlio M. Lima, Ricardo A. Medronho, and Leda R. Castilho

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    Multi-organ platform with tissue-specific niches linked by vascular flow for studies of systemic disease., Kacey Ronaldson-Bouchard

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    Multiscale porous high-temperature heat exchanger using ceramic co-extrusion, Xiangyu Li, Chad Wilson, Olivia Brandt, Rodrigo Orta-Guerra, Jeffrey Youngblood, Rodney Trice, and Evelyn N. Wang

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    Multivalent Influenza vaccine production in HEK-293 cells in response to pandemic threats, Amine Kamen, Cécile Toussaint, Omar Farnos, David Sharon, Alina Venereo-Sanchez, Irene González-Domínguez, Alice Bernier, Xingge Xu, and Hanan Chaabane

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    Mutation of a conserved, hydrophobic, cryptic epitope improves manufacturability and immunogenicity of the SARS-CoV-2 RBD, Sergio Rodriguez Aponte, Neil C. Dalvie, Ting Y. Wong, F. Heath Damron, and J. Christopher Love

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    Nanofiltration Membrane and Liquid Extraction for Rare Earth Separation from Phosphate Ore Waste of Djebel Onk Algeria, Abderraouf Soukeur, Anthony Szymczyk, and Mourad Amara

     

    Nanoindentation-based strength measurements of spherical polymeric micro-samples, Edoardo Rossi, Razvan Lucian Natea, Marco Sebastiani, and Dino D’angelo

     

    Nanoindentation creep testing using the constant contact pressure method, Marcel Sos, Christian Minnert, and Karsten Durst

     

    Nanoindentation induced reversible plasticity detected by acoustic emission, Jaroslav Cech, Radim Čtvrtlík, Petr Haušild, Jan Tomáštík, and Lukáš Václavek

     

    Nanoindentation material testing using SMART and SMART CUBES, Dennis Bedorf, Wolfgang Stein, Martin Knieps, and Daniel Habor

     

    Nanoindentation strain rate jump test-based prediction of fracture and the brittle to ductile transition in tungsten, Kevin Schmalbach, Radhika Laxminarayana, Douglas D. Stauffer, William W. Gerberich, and Nathan A. Mara

     

    Nanoindentation Surface Free Energy measurement over functionalized surfaces and structured substrates, Edoardo Rossi, Razvan Lucian Natea, and Marco Sebastiani

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    Nanomaterials for light-activated tissue repair and wound healing, Kaushal Rege

     

    Nano mechanical and microstructural investigation of damage mechanisms in copper wire bonds, Liz Karanja, Pierre-Yves Pichon, and Marc Legros

     

    Nanomechanical behavior of biodegradable metallic glass for transient electrodes, Seung-Kyun Kang, Jae-Young Bae, Eun-Ji Gwak, and Ju-Young Kim

     

    Nanomechanical characterisation of polymer nanotubes for application as 'soft' mechanical interfaces for biology, Sohini Kar-Narayan

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    Nanomechanical Testing in Materials Research and Development VIII, Sandra Korte-Kerzel

     

    Nanoparticle stabilized thin film metallic glasses, Emese Huszar; Amit Sharma; Liza Szekely; Rejin Raghavan; Ralph Spolenak,; Johann Michler; and Laszlo Petho

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    Nanotechnology in Medicine III: Enabling Next Generation Therapies, Milica Radisic, Victor Shahin, Millicent Sullivan, Josué Sznitman, and Lola Eniola-Adefeso

     

    Natural Alternative Source of Fatty Acids for Phosphate Rock Flotation, André Carlos Silva, Elenice M S Silva, and Leandro O Lopes

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    New Enhanced Technical Capabilities of the ALD SMARTcoater, Ole Hinrichs, Thorsten Hohmann, Dr. Andrzej Nowotnik, and Thomas Schösser

     

    New Environmental-Thermal Barrier Coatings for Ultrahigh Temperature Alloys, Ji-Cheng Zhao, Hua Xie, Wei Zhong, Liangbing Hu, Victor Champagne, David R. Clarke, and Yunhui Gong

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    New insights in formaldehyde-induced detoxification of the tetanus toxin: Chemical modification stoichiometry and characterization of intra- and inter-molecular cross-links, Thierry Eynard, Sébastien Peronin, Amaud Salvador, Fabien Barbirato, Vincent Colombie, Céline Rocca, Nour Al Turihi, Catherine Jourdat, and Jérôme Lemoine

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    New kid on the block: Industrialization of cell-free synthesis for biotherapeutics development, Marcella Yu

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    New process to produce Di-calcium phosphate from low grade rock or tailing using diluted or by-product sulfuric acid, Gauthier Humblet

     

    New reagent scheme for processing Florida phosphate ores, Guoxin Wang and Zhengxing Gu

     

    New techniques for the production of high-performing industrial enzymes, Michael Liszka and Adrienne Davenport

     

    Next generation perfusion process development for production of biologics, Jianlin Xu, Jianfa Ou, Khandaker Siddiquee, Emily Rittershaus, Michael Borys, Anurag Khetan, and Yawen Tang

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    Next wave of microbially expressed Biologics – a step towards synthetic biology, Thomas Sauer

     

    N-mAb: A case study supoorting adoption of integrated continuous bioprocesses, Kevin Brower, Gene Schaefer, and Jennifer L Mantle

     

    Non-destructively capturing CMAS degradation of EB-PVD thermal barrier coatings through 3D confocal Raman renderings, Zachary Stein, Ravisankar Naraparaju, Uwe Schulz, Laurene Tetard, and Seetha Raghavan

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    Novel Cold-Adapted Lipase from Marine Plankton, Salpa thompsoni, Brenda Parker, Alexander Cotton, Dr Iwan Roberts, Professor John Ward, Dr Will Goodall-Copestake, and Dr Brenda Parker

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    Novel human cell models in drug development: How 3D, organoids & organs on chips can improve and renew current paths - and our vision for the future, Adrian Roth

     

    Novel multicomponent equiatomic pyrochlores for future thermal barrier coatings, Maren Lepple and Patrick Hutterer

     

    Novel polymer-derived carbide and boride refractory ceramics, Brad Pindzola, Brad Pindzola, and Paul Chirik

     

    Novel polymer-derived carbide and boride refractory ceramics, Brad Pindzola, Brad Pindzola, and Paul Chirik

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    Novel purification strategies for Influenza neuraminidase-VLPs, Leticia Guzmán-Ruiz, Miriam Klausberger, Florian Krammer, Alois Jungbauer, and Reingard Grabherr

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    Novel technologies are key for the development of live bacterial therapeutics, Christophe Lacroix

     

    On grain boundary migration of a high-angle-grain boundary – Effect of shear stress and energy jump-driving force in micro-bicrystals, Christian Motz, Xiaolei Chen, and Jorge Rafael Velayarce

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    On-Line influenza virus quantification for viral production processes thanks to affinity-based surface plasmon resonance biosensor, Emma Petiot, Laurent Durous, Manuel Rosa-Calatrava, and Christophe A. Marquette

     

    On the contribution of nanomechanical testing to the study of Earth mantle deformations, Patrick Cordier and Hosni Idrissi

     

    On the effects of microstructural orientation on fracture toughness in (V,Al)-nitride and -oxynitride thin films, Markus Reiner Schoof, Soheil Karimi Aghda, Marcus Hans, Carl F. Kusche, Sandra Korte-Kerzel, Jochen M. Schneider, and James S. K.-L. Gibson

     

    On the mechanistic origin of the enhanced strength and ductility in rare earth-based Mg alloys, Henry Ovri, Jurgen Markmann, Hajo Dieringa, and Erica T. Lilleodden

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    Optimisation of an alkaline lysis process for a plug- and play plasmid DNA production, Fatma Mohamed Ebrahim Alhamer Almulla and Eli Keshavarz-Moore

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    Optimisation of an alkaline lysis process for a plug- and play plasmid DNA production, Fatma Almulla and Eli Keshavarz-Moore

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    Optimising mRNA vaccines manufacturing by using Machine learning approaches, Sara Sousa Rosa, Sara Sousa Rosa, Davide Nunes, Luis Antunes, Duarte MF Prazeres, and Ana M. Azevedo

     

    Optimization of a dynamic perfusion process using a combination of high throughput experimentation and hybrid modeling approaches, Maarten Pennings, Jake Chng, Ng Say Kong, Chris McReady, and Gerben Zijlstra

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    Optimization of E. coli SoluPro ® using synthetic biology to generate high-performance microbes for scalable production of protein therapeutics, Drew Tack

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    Optimization of rAd5 vectored Newcastle vaccine production in HEK293 at high cell densities, Samia Rourou, Amani Chaaben, Alya Soudani, Meriem Ben Zakour, Omar Farnós, Esayas Gelaye, Martha Yami, Amine Kamen, Khaled Trabelsi, and Héla Kallel

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    Optimization, production, purification and characterization of HIV-1 Gag VLPs functionalized with SARS-CoV-2 Spike glycoprotein, Amau Boix-Besora, Elianet Lorenzo, Jesus Lavado-Garcia, Francesc Gòdia, and Laura Cervera

     

    Optimizing enzyme production to support commercial mRNA manufacturing, Juozas Siurkus

     

    Optomechanics of small-scale structures, Ralph Spolenak, Joan Sendra Garcia, and Micha Calvo

     

    Orientation-dependent plastic deformability in micropillar compression of oxide ceramics, Hiroshi Masuda, Yelm Okuyama, and Hidehiro Yoshida

     

    Orientation, temperature and strain rate effects in deformation twinning of magnesium, Xavier Maeder, Nicolo della Ventura, Szilvia Kalacska, Amit Sharma, Daniele Casari, Thomas E.J. Edwards, and Johann Michler

     

    Oscillatory flow reactor: A solution for continuous bioprocessing, Diogo Ferreira-Faria, Filipa D. Moreira, M. Raquel Aires-Barros, Ana M. Azevedo, and António Ferreira

     

    Overcoming cell therapy manufacturing barriers through innovation and partnership, Rupa Pike

     

    Overcoming challenges in organofluorine biosynthesis by engineered fluorinases, Pravin Kumar, Anuj Shetty, Naveen Banchallihundi Krishna, Jiri Damborsky, Pablo Ivan Nikel, Roopa Lalitha, and Gladstone Sigamani

     

    Overcoming challenges in organofluorine biosynthesis by engineered fluorinases, Pravin Kumar, Anuj Shetty, Naveen Banchallihundi Krishna, Jiri Damborsky, Pablo Ivan Nikel, Roopa Lalitha, and Gladstone Sigamani

     

    Overcoming key challenges during the upstream development of a continous manufacturing process at 500L scale, Leon Pybus, Charles Heise, Tibor Nagy, and Jonathan Haigh

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    Overviews of vaccine technology for neglected diseases in developing Latin America country - Peru, Karen D. Calvay Sanchez, Yanina Zarate Sulca, and Giovanna Mendoza Mujica

     

    Oxidation behavior of Cf / MC – MB2 – SiC (with M = Hf, Zr) composites in an oxyacetylene torch environment, Thomas Bourdeau, Laurence Maillé, Yann Le Petitcorps, Pierre Bertrand, Alexandre Allemand, and Francis Rebillat

     

    Oxidation behavior of Cf / MC – SiC (with M = Hf, Zr) composites in an oxyacetylene torch environment under over oxygen concentration, Thomas Bourdeau, Laurence Maillé, Yann Le Petitcorps, Pierre Bertrand, Alexandre Allemand, and Francis Rebillat

     

    Oxidation kinetics of sub-stoichiometric ZrCX via furnace testing to 2500˚C / 1 atm air, Mark Opeka, James Hawbaker, and Bhavesh Patel

     

    Oxidation of high entropy ultra-high temperature ceramics, Elizabeth Opila, Joshua Gild, Kenneth Vecchio, Jian Luo, Tyler Harrington, and Elizabeth Opila

     

    Oxidation of TaC-HfC blends densified by spark plasma sintering, Maritza Sanchez, Dr. Lisa Rueschhoff, and Dr. Olivia Graeve

     

    Parker Solar Probe, Elizabeth Congdon

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    Pathway design for mixotrophic production of biochemicals from CO2 and methanol in yeasts, Golnaz Memari, Özge Ata, and Diethard Mattanovich

     

    Pathways to evaluate and improve the sustainability of plastics – an overview, Hans-Josef Endres

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    Personalizing the treatment of Parkinson’s disease using a multi-sensor integrated midbrain organoid-on-a-chip platform, Peter Ertl

     

    PET recycling: From enzyme engineering to a first industrial unit, Alain Marty, Vincent Tournier, Nicolas Chabot, Guy Lippens, Isabelle André, and Sophie Duquesne

     

    Phase evolution in thermally annealed metallic-UHTC composites, Michael Large, Tyler Kaub, Christopher R. Weinberger, and Gregory B. Thompson

     

    Phase transformations and local deformation mechanisms - A case study on Cu 20 m.% Sn, Lea Lumper, Johann Kappacher, Verena Maier-Kiener, and Helmut Clemens

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    Phosphate Rock Beneficiation through Production of DCP “Super-Rock” as a Raw Material for Phosphoric Acid Plants, Sébastien Havelange

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    Photoablation of human vitreous opacities by light-induced vapor nanobubbles, Stefaan De Smedt

     

    Photoenzymatic Catalysis - Using light to reveal new enzyme functions, Todd Hyster

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    Photothermal nanoparticle-based approaches to designing immunoengineered therapies for cancer, Rohan Fernandez

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    Pichia pastoris, a promising microbial cell factory for continuous manufacturing, Xavier Garcia-Ortega, José Luis Montesinos-Seguí, and Francisco Valero

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    Pichia production host engineering by systemic host changes, Christoph Kiziak, Núria Adelantado, Jennifer Staudacherb, Corinna Rebneggerb, Brigitte Gasserbc, and Diethard Mattanovich

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    Pilot-scale integrated continuous biomanufacturing for monoclonal antibodies including mild pH, Veronique Chotteau, Hubert Schwarz, Joaquín Gomis Fons, Madelène Isaksson, Julia Scheffel, Andreas Castan, Sophia Hober, and Bernt Nilsson

     

    Pilot scale technical establishment and commercial scale business case on integrated continuous biomanufacturing, Takuo Kawase

     

    Plasma-activated EB-PVD of protective coatings: tools and processes, Burkhard Zimmerman, Gösta Mattausch, and Bert Scheffel

     

    Plasma wind tunnel testing of UHTC coated components for hypersonic applications, Mario De Stefano Fumo, Roberto Gardi, Stefania Cantoni, Mario Tului, Marco Fortunato, Francesca Arcobello Varlese, and tefano Lionetti

     

    Plastic deformation of microsamples: Intermittent dislocation avalanches and their acoustic emission, David Ugi, Peter Dusan Ispanovity, Istvan Groma, Szilvia Kalacska, Edit Szilagyi, and Kristian Mathis

     

    Plastic flow and structural heterogeneities in silicate glasses - A high throughput investigation, Etienne Barthel, C. Martinet, E. Burov, J. Teisseire, and B. Rufflé

     

    Plasticity in nanoscale friction: Static and dynamic, John Pethica, Owen Brazil, and George M. Pharr

     

    Plasticity of the C15-CaAl2 Laves phase at room temperature, Carl F. Kusche, Doreen Andre, Pei-Ling Sun, Nicolas J. Peter, and Sandra Korte-Kerzel

     

    Plasticity of the CaAl2 phase and its change with Mg addition at room temperature, Martina Freund, Doreen Andre, Carl Kusche, Sandra Korte-Kerzel, and Pei-Ling Sun

     

    Plasticity of topologically close-packed phases in the Fe-Ta(-Al) system, Christina Gasper, James S. K.-L Gibson, Wei Luo, Hauke Springer, Stefanie Sandlobes-Haut, and Sandra Korte-Kerzel

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    Plasticity of ZrB2 grains during micropillar compression: The effect of anisotropy, temperature and dislocations, Tamás Csanádi, Jenő Gubicza, Michael J. Reece, William G. Fahrenholtz, and Ján Dusza

     

    Platform approaches to mRNA analytical testing methods, Amy Glekas

     

    Plug-and-play software for mechanistic modelling of end-to-end continuous manufacturing of monoclonal antibodies, Moo Sun Hong, Amos E. Lu, and Richard D. Braatz

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    Pollution to products: Recycling of “above ground” carbon by gas fermentation, Michael Koepke

     

    Porous UHTCs for transpiration cooling of hypersonic flight, Rowan Hedgecock and Luc Vandeperre

     

    Post-approval changes to disposables/SUS, Patricia Hughes

     

    Potential Circularity of Plastic in Europe – Dynamic MFA of PET, PE & PP Flows, Marie K. Eriksen and Thomas F. Astrup

     

    Powering computational enzyme design with natural evolutionary information, Wenjun Xie and Arieh Warshel

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    Pre-fabrication for providing biocapacity to support vaccine manufacturing, Martin Birch and Thomas Hauser

     

    Preliminary evaluation of PendoTECH® single use sensors post X-ray irradiation, Nick Troise and James Furey

     

    Preliminary metabolic screening method for clone selection in the ambr15, Christine Ferng, Ken Lee, and Jon Coffman

     

    Proactive and reactive supply chain strategies for risk mitigation, Hana Sheikh

     

    Process Analytical Technology (PAT) for automated, real-time control of continuous manufacturing of mAbs, Shantanu Banerjee and Garima Thakur

     

    Process and analytical development challenges for the incorporation of gene edits into T cell therapies, Thomas Brieva

     

    Process and cost modeling approaches for manufacturing operations utilizing multi- column chromatography applications, Mattia Sponchioni, Juan Jose Romero Conde, James Angelo, Sanchayita Ghose, Xuankuo Xu, Tae Keun Kim, and Massimo Morbidelli

     

    Process developent of a serum-free and scalable lentiviral vector manufacturing platform for cellular immunotherapies, Carme Ripoll Fiol, Dale Stibbs, Qasim Rafiq, and John Welsh

     

    Process development and scale-up for gene circuit engineered CAR-NK cell manufacturing, Travis Wood, Dharini Iyer, Wesley Gorman, Carmina Blanco, Abla Bakir, Haritha Lakshmireddy, Charity Vilchez Juang, Denny Nguyen, and Philip Lee

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    Process development for a flexible vaccine vector platform based on recombinant life virus, Dieter Palmberger,; Shirin Preinsperger; Willibald Steinfellner; Matthias Müllner; Alois Jungbauer; and Kerstin Rumpelmayr

     

    Process development for improved Car-t production utilizing an automated perfusion stirred-tank bioreactor, Tiffany Hood, Fern Slingby, Winfred Geis, Viktor Sander, Nicola Bevan, Quentin Vicard, and Qasim A. Rafiq

     

    Process development for improved Car-t production utilizing an automated single use perfusion stirred-tank bioreactor, Tiffany Hood, Fern Slingby, Quentin Vicard, Nicola Bevan, Viktor Sander, Winfried Geis, and Qasim A. Rafiq

     

    Process development of a serum-free and scalable lentiviral vector manufacturing platform for cellular immunotherapies, Carme Ripoll Fiol, Dale Stibbs, John Welsh, and Qasim Rafiq

     

    Process development of a serum-free and scalable lentiviral vector production in a single-use bioreactor, Carme Ripoll Fiol, John Welsh, and Qasim Rafiq

     

    Process economics evaluation of Adeno-associated Viral Vector (AAV) manufacturing, Annabel Lyle, Christos Stamatis, Martyn Hulley, Thomas Lin, Albert Schmelzer, Richard Turner, and Suzanne Farid

     

    Processing and Characterization of Ytterbium Silicate Environmental Barrier Coatings, Ping Xiao, Ahmet Hilmi Paksoy, Esma Yilmaz, and Simon M cCormack

     

    Processing of high entropy carbide based ceramics, Lavina Backman, Heonjune Ryou, James Wollmershauser, Syed Qadri, Edward P. Gorzkowski, and Jesse Maxwell

     

    Process intensification combined with Adaptive Laboratory Evolution enhance VLP- based vaccine candidates production in insect cells, Ricardo Correia, Bárbara Fernandes, Paula M. Alves, and António Roldão

     

    Process intensification: Impact on cost, facility footprint and sustainability matrix, Miriam Monge, David Pollard, Priyanka Gupta, and Andrew Sinclair

     

    Process intensification: Modeling the impact of technology and process scenario selection on cost, throughput, facility volume, footprint and sustainability, Priyanka Gupta

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    Process intensification - So much more than continuous bioprocessing, Niklas Jungnelius and Marc Bisschops

     

    Process optimization for adenovirus-based viral vector vaccines, Annabel Lyle, Christos Stamatis, Martyn Hulley, Thomas Linke, Albert Schmelzer, Richard Turner, and Suzanne Farid

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    Producing viruses in orbit: Current developments for orbital shaken viral vaccine manufacturing, Tim Bürgin, Juliana Coronel, Katharina Fiddeke, Volker Sandig, Yvonne Genzel, Udo Reichl, and Tibor Anderlei

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    Product and host engineering for low-cost manufacturing of therapeutic proteins in yeast, Neil Dalvie

    PDF

    Production and characterization of hepatitis B Virus-like Particles expressed in HEK293 and CHO-K1 recombinant cell lines. Analysis of the humoral immune response, Juan Manuel Battagliotti, Diego Fontana, Marina Etcheverrigaray, and Claudio Prieto

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    Production and purification of an immunogenic G protein of rabies virus from S2 insect cells, Renato Mancini Astray, Livia Pillati, Mayra Pereira Rocca, Flavia Ferreira Barbosa, Helio Langoni, Benedito Menozzi, Soraia Attie Calil Jorge, and Elisabeth Augusto

     

    Production of a fusogenic oncolytic rVSV-NDV virus: Cell-line screening and process development in small-scale suspension cultures, Sven Göbel, Fabian Kortum, Karim Jaén Chavez, Ingo Jordan, Jennifer Altomonte, Yvonne Genzel, and Udo Reichl

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    Production of a fusogenic oncolytic rVSV-NDV virus in perfusion processes, Sven Göbel, Marie Dorn, Karim Jaén Chavez, Ingo Jordan, Volker Sandig, Jennifer Altomente, Yvonne Genzel, and Udo Reichl

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    Production of high-quality SARS-CoV-2 antigens for vaccine development and serological assays implementation, Bárbara Fernandes, Rute Castro, Patricia Gomes-Alves, Mario Amacker, Toon Stegmann, Sylvain Fleury, Paula M. Alves, and António Roldão

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    Production of influenza A virus defective interfering particles in a high cell density perfusion cultivation with continuous virus harvesting, Marc D. Hein, Anshika Chawla, Prerna Arora, Maurizio Cattaneo, Michael Winkler, Stefan Pöhlmann, Klaus Schughart, Yvonne Genzel, Sascha Y. Kupke, and Udo Reichl

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    Production of influenza virus-like particles by insect cells and removal of baculovirus from virus-like particles and other extracellular vesicles, Alois Jungbauer, Katrin Reiter, Patricia Aguilar, Miriam Klausberger, Florian Strobl, Wolfgang Ernst, Gerald Striedner, and Reingard Grabherr

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    Production of monoclonal antibodies specific to soluble proteins of Bartonella bacilliformis, Yanina Zarate Sulca, Yolanda Medina, Karen D. Calvay Sanchez, and Giovanna Mendonza Mujica

     

    Progress in the development of high strain rate nanoindentation testing, George Pharr

     

    Progress towards making a global supply of microbial extracellular vesicles,100-times cheaper than a typical biologic, Collin McKenna, Johannes Kung, Fabian R omano-Chernac, Emanuele Leoncini, and Bato Jaric

     

    Proof-of-concept of a novel scalable magnetic bead-based cell separation technology, Nils Brechmann, Kristofer Eriksson, and Véronique Chotteau

     

    Prospective dynamic resource assessment of circular economy solutions: the case of batteries in the mining sector, Harald Helander

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    Prospective life cycle assessment for nickel slag valorization by mineral carbonation, Eva Quéheille; Anne Ventura; Laurédan Le Guen,; and Michel Dauvergne

     

    Prospects of development smart collectors for phosphorite flotation: nanoparticles- based collectors, Gary Albarelli

     

    Protective complex oxide film formation in multi-component ultra-high temperature carbides during plasma jet exposure, Ambreen Nisar, Tamil Sakthivel, Cheng Zhang, Benjamin Beosl, Sudipta Seal, and Arvind Agarwal

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    Protein design and immunogenic analysis of COVID-19 vaccine candidates based on RBD/trimeric-spike antigens and chimeric VLPs antigens, Claudio Prieto, Ernesto Garay, Javier Villarraza, Antonela Fuselli, Agustina Gugliotta, Celeste Rodríguez, Victoria Gastaldi, Natalia Ceaglio, and Diego Fontana

     

    Protein design using deep learning, David Baker

     

    Protocol development to overcome bioprocess bottlenecks in the large-scale expansion of high quality hIPSC aggregates in vertical-wheel bioreactors, Breanna Borys, Tiffany Dang, Sunghoon Jung, Brian Lee, and Michael S. Kallos

     

    QM/MM Studies of The phenylalanine ammonia-lyase variants helped to understand the mechanistic role of the mutations, Naveen Banchallihundi Krishna, Pravin Kumar, Anuj Shetty, Gladstone G. Sigamani, Vikas D. Trivedi, Karishma Mohan, Athreya Ramesh, Nikhil U. Nair, and Todd C. Chappell

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    Qualifying X-ray irradiation of single-use systems to address new challenges associated with single-use growth, James Hathcock

     

    Quality implications of cryopreservation: Building a small-scale model to determine the shelf-life of cryopreserved blood products for drug product manufacturing, Purna Venkataraman, Lusine Bozoyan, Craig Jones, Francis John Pierciey, and Lesley Chan

     

    Quantitative measurement of stress vs. strain in supported thin films by the layer compression test, Aaron D. Sinnott

     

    µRAMOS: Online monitoring of respiration activities in 96-Deepwell Microtiter plates, Robert Dinger, Clemens Lattermann, David Flitsch, and Jochen Büchs

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    Rapid and high yield microbial protein production system for human and animal vaccines: C1 Filamentous fungus Thermothelomyces heterothallica, Noelia Valbuena

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    Rapid iterative design of tandem-core virus-like particles using Escherichia coli- based cell-free protein synthesis, Daniel G. Bracewell, Jaime Teneb-Lobos, Stefanie Frank, Daniel G. Bracewell, Beatrice Melinek, Alex Ramirez, and William Rosenberg

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    Rapid iterative design of tandem-core virus-like particles using Escherichia Coli-based cell-free protein synthesis, Beatrice Melinek, Jaime Teneb-Lobos, Beatrice Melinek, Stefanie Frank, Alex Ramirez, William Rosenberg, and Daniel G. Bracewell

     

    Rapid product characterization for release using membrane microscopy, Adam Ross

     

    Rare Earths in Phosphate: Occurrence, Significance and Opportunities for Recovery, Patrick Zhang

     

    Rare earths recovery and gypsum upgrade from Florida phosphogypsum, Patrick Zhang

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    Rational design, expression and characterization of chimeric rabies VLPs displaying the major antigenic site of Foot and Mouth Disease Virus, Ernesto Garay, Diego Fontana, Lautaro Leschiutta, Ricardo Kratje, and Claudio Prieto

     

    Reactions in Thermal Barrier Coatings and Multi-Mineral Dusts in a Gas Turbine Engine Dust Ingestion Test, Gyn Brewster, Daniel Everington, Rory Clarkson, Jacob Elms, Alison Pawley, João Martins, and Ping Xiao

     

    Reactions of rare earth hafnates and zirconates with silicate melts of different basicity, Andrew R. Ericks, Carlos G. Levi, and Frank W. Zok

     

    Real-time model-based control of single pass tangential flow filtration for production of monoclonal antibodies, Venkataramana Runkana, Garima Thakur, Vishnu Swaroopji Masampally, Amey Kulkarni, Navnath Deore, Anurag Rathore, and Venkataramana Runkana

     

    Real-time process analytical technology: Fluorescent dye-based miniaturized sensor for aggregate detection, Mariana Neves Sao Pedro, Michel H.M. Eppink, and Marcel Ottens

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    Recapitulating Complex Human Tissues using organ-on-chip and organoid Technologies, Peter Loskill

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    Recovery of Valuable Elements from Phosphate Water Processing by Dissolved Air Flotation Technique, Mustapha Adjadi, Abbes HAMMANI, and Mourad Amara

     

    Reduction of water and water-related energy consumption by in-situ media and buffer preparation on demand in continuous integrated, Daniel Komuczki, Alois Jungbauer, Daniel Komuczki, Tommaso De Santis, and Peter Satzer

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    Refactoring yeast central metabolism to reverse growth phenotypes and Product formation, Diethard Mattanovich

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    Reimagining biomanufacturing for equitable access to medicines: The Resilience Story, Rahul Singhvi

     

    Repair for high‐voltage electric motors: energy efficiency vs resource use?, Adeline Jerome, Maria Ljunggren, and Matty Janssen

     

    Requirements and Design Constraints for TBC’s in Land Based Gas Turbines, Grégoire Witz, Arturo Flores Renteria, Jens-Erich Döring, Cora Hitchman, Roy Patgunarajah, Atin Sharma, Anirudha Vaidya, and Neil Hitchman

     

    Residence time distribution of continuous protein a chromatography, Narges Lali, Peter Satzer, and Alois Jungbauer

     

    Review of MgO Removal Processes for Florida Rock, Charles Guan

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    RHABDO-LIKE RECOMBINANTE (VLPs), a novel veterinary rabies vaccine: Safety and efficacy trials in pets and cattle, Claudio Prieto, Diego Fontana, Federico Marsili, Ricardo Kratje, and Marina Etcheverrigaray

     

    Risk-based qualification of X-ray sterilization for single-use systems, Timo Neumann, Jessica Shea, Monica Cardona, and Paul Killian

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    Robust protein production and secretion in bacteria using type III secretion system, Danielle Tullman-Ereck

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    Robust, reliable and controlled bio-methane production, Behnam Taidi

     

    Role of grain boundary on the deformation of micropillars, Manmath Dash, Longfangdi Shi, Zhaoxuan Wu, and Zhaoxuan Wu

    PDF

    Rotavirus VP6 nanotubes show an antigen form-dependent adjuvant activity: Zika virus envelope protein monomer vs Zika virus-like particles, Arturo Liñan, Ana Ruth Pastor, Selene J. Uribe-Romero, Mabel Rodriguez, Octavio T. Ramirez, and Laura A. Palomares

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    Salt tolerant endonucleases for the removal of host cell DNA in Downstream Processing of enveloped viruses, Viktoria Mayer, Patricia Pereira Aguilar, and Alois Jungbauer

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    SARS-CoV-2 and Ebola: CHO-based manufacturing provides high quality subunit-vaccine candidates and diagnostics, Paco Pino

     

    SARS-COV-2 production in a single-use scalable high cell density bioreactor, Anna Offersgaard; Carlos Rene Duarte Hernandez; Anne Finne Pihl; Rui Costa; Nandini Prabhakar Venkatesan,; Xiangliang Lin; Long Van Pham; Shan Feng; Ulrik Fahnøe; Troels Kasper Høyer Scheel; Santseharay Ramirez; Udo Reichl; Jens Bukh; Yvonne Genzel; and Judith Margarete Gottwein

     

    Scalable downstream process development and manufacturing in cGMP for human iPSC derived products, Sho Sato, Tomoaki Kurakazu, Hideaki Kagawa, Yina Santiago-Rodriguez, and Peter Fuhrken

     

    Scalable downstream purification of recombinant adeno-associated viral vectors, Sarah Blackmore, Todd P. Sanderson, Mark Schofield, Nick Marchand, Aydin Kavara, Adam Hejmowski, Shawn Tansey, Rajeshwar Channawar, Michelle Olson, Anne MacIntyre, Amanda Rose, Kurt Boenning, Julio Huato, and Mike Collins

     

    Scale-down of an orbital shaken bioreactor: High cell density cultivation in perfusion mode and virus production, Sven Göbel, Lars Pelz, Ilona Behrendt, Matthias Proemmel, Jennifer Altomonte, Tibor Anderlei, Tim Bürgin, Yvonne Genzel, and Udo Reichl

     

    Scaling viral vector production processes into HyPerforma DynaDrive Single-Use Bioreactors, Paula Decaria and Katelyn Parkinson

     

    Scientific solutions for regulatory guidelines: Unlocking AAV product testing, Stuart Wright

     

    Screening millions of droplet-compartmentalized single cells with Xdrop®, Peter Mouritzen, Rikke Stick Højmark, and Marie Just Mikkelsen

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    Selective in vitro loading of proteins into protein nanocompartments for applications in the bioindustry, Alexander Van de Steen and Stefanie Frank

     

    Selective Thermal Emission Coatings for Improved Turbine Efficiency, Pete McGrail, Bruce Bernacki, Charles Bonham, John Loring, Molly O’Connor, Todd Schaef, Jeromy Jenks, Darick Baker, and Ognjen Ilic

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    Semi-rational engineering of Adh2 for improved methanol utilization in Komagataella phaffii, Charles Moritz, Enikö Hermann, Clemens Peterbauer, and Diethard Mattanovich

     

    Shear-coupling migration of grain boundaries in UFG Al, Marc Legro, Romain Gautier, Oliver Renk, Nicolas Combe, and Christophe Coupeau

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    Shifting the paradigm from global to national: innovative approaches for sustainable production of priority vaccines, Birgitte Giersing

     

    Short-range chemical environment versus long-range chemical homogeneity analyses in high-entropy transition metal AlB2-type diboride solid solutions, Frederic Monteverde, Federico Saraga, Mattia Gaboardi, Lun Feng, Gregory Hilmas, and William Fahrenholtz

     

    SiC-based/EBC Coating systems investigated by LASAT (LAser Shock Adhesion Test), Vincent Guipont, Julie Chalony, Vincent Maurel, Melvin Le Nevé, Emine Bakan, Robert Vaßen, Dietmar Koch, Thomas Vandellos, and Thomas Philippe

     

    Simulated control strategy for product diversion management during continuous processing, Thomas Ransohoff, Behnam Partopour, Ahsan Munir, Thomas Erdenberger, Huanchun Cui, and Rui Wheaton

     

    Simulations of Oxide Growth and Stress Evolution in Silicon-based Coatings and Composites, Matt Begley, Stephen Sehr, Virginia Collier, and Frank Zok

     

    Simultaneous residual stress mapping of topcoat and TGO in APS TBC using combined micro-raman-PL spectroscopy, Srikanth Batna, G. Siva Kumar, and Ashutosh S. Gandhi

     

    Simultaneous residual stress mapping of topcoat and TGO in APS TBC using combined micro-raman-PL spectroscopy, Srikanth Batna, G. Siva Kumar, and Ashutosh S. Gandhi

     

    Single-cell Multi-omics for accelerated therapeutic characterization and release, Yan Zhang

     

    Single-Use optical and electrochemical pH sensors in upstream bioprocessing, Erica Berilla

     

    Size-dependent coherent twin boundary strength contribution in Cu micropillars, Reza Hosseinabadi, Heinz Riesch-Oppermann, James P. Best, Gerhard Dehm, and Christoph Kirchlechner

     

    Size effects in fracture mechanics: A detailed investigation on crack growth at the micro- and mesoscale, Jutta Luksch, Aloshious Lambai, Gaurav Mohanty, Florian Schafer, and Christian Motz

     

    Slip and deformation behavior in intermetallic Cobalt-Samarium phases, Tobias Stollenwerk, Zhuocheng Xie, Navid Shayanfar, Konstantin Skokov, Sandra Korte-Kerzel, Oliver Gutfleisch, and Pei-Ling Sun

     

    Smart Road with Phosphogypsum as Road Base, Gary Albarelli, Patrick Zhang, and James Mennie

     

    Social Life Cycle Assessment of formal and informal recycling sector, Marzia Traverso

     

    Solid polyethylene glycol precipitation: Potential cost reduction in antibody downstream processing, Maria del Carme Pons Royo, Acib; Tommaso De Santis; Daniel Komuczki; Alois Jungbauer; and Peter Satzer

     

    Solid solution hardening effects on structural evolution and mechanical properties of nanostructured high entropy alloys, Karsten Durst, Tom Keil, Christian Minnert, and Enrico Bruder

     

    Spatially resolved characterization of thermally grown oxides using time-domain thermoreflectance, Milena Milich and Patrick Hopkins

     

    Spherical indentation study on incipient plasticity of medium-/high-entropy alloys, A-Hyun Jeon, Yakai Zhao, Zhe Gao, Upadrasta Ramamurty, and Jae-il Jang

     

    Stabilization Mechanism and CMAS Corrosion Behavior of Rare Earth Oxides Based Environmental Barrier Coatings Prepared by Thermal Spray, Naoki Yamazaki

     

    Standardization of visible particles measurement in single-use systems, an advantage for the emerging applications, Fanny Gaston Melanie Gauthier,; Klaus Wormuth; Melanie Gauthier; Nelly Montenay; and Veronique Cantin

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    Sterile filtration of large biomolecules - New insights using live attenuated vaccines and model particle suspensions, Adam Kristopeit, Wanli Ma, Sheng-ching Wang, Neil Taylor, and Andrew Zydney

     

    Strategies for printing fibers and post-processing for ceramic matrix composites (CMCs), Corson Cramer, David Mitchell, Vlastimil Kunc, and James Klett

     

    Stress distribution analysis in zirconium diboride and silica carbide (ZrB2- SiC) based thermal protection system under hypersonic flight conditions using a machine learning driven approach, Carmine Zuccarini, K Ramachandran, DD Jayaseelan, and Y.C.J. Mudiyanselage

     

    Strong, stiff & auxetic - Lessons learned from a fascinating biological material, Daniel Kiener, Jin-Kyung Kim, Yue Liu, Michael Wurmshuber, Xiang-Long Peng, Jinsol Seo, Jiwon Jeong, Zhen Wang, Jana Wilmers, Celal Soyarslan, Jongil Kim, Boonsita Kittiwirayanon, Jeehun Jeong, Hyo-Jeong Kim, Yang Hoon Huh, Swantje Bargmann, Huajian Gao, and Sang Ho Oh

     

    Study of mechanical behavior on single use bags welding under gamma irradiation, Nina Perier, Fanny Gaston, Nathalie Dupuy, Sylvain R. A Marque, Lucie Delaunay, and Samuel Dorey

     

    Successes, Challenges and Opportunities for Environmental Barrier Coatings, Julie Kuhn, Nicholas Antolino, Vidya Ramaswamy, Nathaniel Brown, and Mano Manoharan

     

    Successful transition from fed-batch to continuous manufacturing within a mAb process development cycle, Karthik P. Jayapal, Sri R Madabhushi, Michael A Rauscher, and Matthew Manahan

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    Superior SARS-CoV-2 RBD antigen designs for highly specific, quantitative serotests, Miriam Klausberger, Mark Dürkop, Nikolaus Kienzl, Gerhard Stadlmayr, Lukas Mach, Gordana Wozniak-Knopp, and Reingard Grabherr

     

    Supply of customized Single-Use-Mixer’s under tight circumstances became an issue under COVID, Per Stobbe

     

    Supporting a circular economy strategy in South Tyrol, Italy: Integrated life-cycle energy and greenhouse gas analysis, Joana Bastos, Antonello Durante, Samuele Zilio, Valentina D’Alonzo, and Gianluca Grazieschi

     

    Supporting a circular economy strategy in South Tyrol, Italy: Integrated life‐cycle energy and greenhouse gas analysis, Joana Bastos, Gianluca Grazieschi, Antonello Durante, Samuele Zilio, and Valentina D’Alonzo

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    Suspension Vero cell culture technology for high titer production of viral vaccines, Chun Fang Shen, Rénald Gilbert, Elodie Burney, Seyyed Mehdy Elahi, Stephane Lanthier, Amine Kamen, and Martin Loignon

     

    Sustainability Programs of the Arab Fertilizer Association, Mahamed Ali

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    Sustainable resins for single-use technologies, Hans de Brouwer

     

    Synergy of collectors for phosphate flotation in Serra do Salitre Complex, Gabriela Budemberg, Franciele Lima, Santiago Cruz, and Andre Soares Braga

     

    Synthesis and characterization of compositionally complex zirconate and phosphates, Daniel Mumm

     

    Synthesis and crystallography of high entropy metal carbides: A new class of ultrahigh temperature and irradiation resistant ceramics, Olivia A. Graeve, Ved Vakharia, and Luyao Zhang

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    Synthesis, densification, and properties of high entropy ultra-high temperature ceramics, William Fahrenholtz, Lun Feng, and Greg Hilmas

     

    Synthesis of multi component rare-earth silicate systems for T/EBC application: Study of their high temperature interactions with CMAS, Cynthia Yanel Guijosa Garcia, Peter Mechnich, Ravisankar Naraparaju, and Uwe Schulz

     

    System Level Life Cycle Assessment Models for EU and National Waste Management, Josefine H. Sund and Thomas Fruergaard Astrup

     

    Systems-level discovery of quality attributes and candidate pathways for optimized production of human pluripotent stem cell-derived cardiomyocytes, Aaron Simmons, Elizabeth F. Bayne, Yanlong Zhu, Ying Ge, and Sean P. Palecek

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    Tackling a capacity bottleneck to permit large-scale downstream processing of an adenovirus-vectored vaccine, Carina Citra Dewi Joe, Thomas Linke, Piergiuseppe Nestola, Yuanyuan Li, Rameswara R. Segireddy, Richard Turner, and Alexander D. Douglas

     

    Tailoring thin-film mechanical fragmentation properties of hybrid atomic/molecular-layer-deposited materials, Ivo Utke, Janne-Petteri Niemela, Barbara Putz, and Johann Michler

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    Targeted in vivo drug delivery with focused ultrasound, Naomi Matsuura

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    Targeting endogenous retroviruses using a novel adenoviral vaccine technology, Anne-Marie Andersson, Emeline Ragonnaud, Joana D. Boluña, Isabella S. Pedersen, Amaia V. Bermejo, Lasse Neukirch, Karen N. Nielsen, Silke Schroedel, Christian Thirion, and Peter J. Holst

     

    Technical and Environmental Performances of Alternative Thermochemical Treatments for Mixed Plastics Waste, Filomena Ardolino, Francesco Parrillo, and Umberto Arena

     

    Temperature-dependance evalutation on deformation processes in the Alloy 718 using high-resolution digital image correlation, Damien Texier, Julien Milanese, Eric Andrieu, Jean-Charles Stinville, and Marc Legros

     

    Temperature-dependent dynamic plasticity of micro-scale fused silica, Remo Widmer, Alexander Groetsch, Guillaume. Kermouche, Ana Diaz, Manish Jain, Rajaprakash Ramachandramoorthy, Laszlo Pethö, Jakob Schwiedrzik, and Johann Michler

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    Test tubes and turnaround times: An accelerated biosafety testing approach for new vaccines against emerging pathogens, Sarah Sheridan

     

    Textured UHTC borides using extremely low magnetic fields: influence of colloidal processing parameters and material selection, Juan Diego Shiraishi and Carolina Tallon

     

    The AM3aC2A Project: Multiscale approach for modeling CMC and UHTCMC materials for reusable components for aerospace, Mario De Stefano Fumo, Alessandro Airoldi, Lorenzo Cavalli, Diletta Sciti, and Elena Vellutini

     

    The Biofactory: Life Cycle Sustainability Assessment for Promoting Circular Economies in Wastewater TreatmentMadeline Furness, University of Canterbury, United Kingdom, Madeline Furness, Rolando Chamy Maggi, and Ricardo Bello Mendoza

     

    The calibration of nanoindenters revisited, Thomas Chudoba

     

    The challenges of performing high density perfusion processes in single use bioreactors, Anita Dabek, Anthony Beaney, Mauran Mahendra, Anastasia Eftychidou, Colin Jaques, Joanna Kolacz, and Mikayla Olin

     

    The development of polymer-derived Si(Al)CN CMC for high temperature applications, Muhammed Younas

     

    The ductility of thin freestanding metallic films investigated by in-situ TEM / AFM nanomechanical testing, Benoit Merle

     

    The effect of size, crystal orientation and temperature on the deformation of cast microwires, Luciano Borasi, Simone Frasca, Edoardo Charbon, and Andreas Mortensen

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    The effect of the production method on the quality of coronavirus spike protein RBD variants of concern: Implications on the specificity and sensitivity of serological assays, Daniel Barreto, Michelle Gutiérrez, Fernando Losoya, Alberto Porras, Violeta Guadarrama, Vanessa Hernández, Dubhe Bulté, Laura A. Palomares, and Octavio T. Ramírez

     

    The environmental benefits of circular economy strategies in the nuclear industry: A Life Cycle Assessment study, Andrea Paulillo, Martina Pucciarelli, Stephen J. Palethorpe, Anthony Banford, Julian Spencer, and Paola Lettieri

     

    The Environmental Impact of Wasting Recoverable Nutrients From Treated Sewage Sludge for Agricultural Use: A Life Cycle Assessment For a Circular Economy, Esra Aleisa, Abdalrahman Alsulaili, and Yasmeen Almuzaini

     

    The impact of baffles and probes on flow and power consumption in single- use bioreactors, Artemis Danae Charalambidou, Tom Wyrobnik, Anne de Lamotte, Andrea Ducci, and Martina Micheletti

     

    The impact of bioinformatics on industrial enzyme engineering, Andreas Vogel

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    The implication of glycans on the ACE2: SARS-CoV-2 spike interaction, Manuel Reithofer, Rong Zhu, Yoo Jin Oh, Reingard Grabherr, Peter Hinterdorfer, and Miriam Klausberger

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    The inactivated NDV-HXP-S COVID-19 vaccine induces a significantly higher ratio of neutralizing to non-neutralizing antibodies in humans as compared to mRNA vaccines, Juan Manuel Carreño, Ariel Raskin, Gagandeep Singh, Johnstone Tcheou, Hisaaki Kawabata, Charles Gleason, Komal Srivastava, Vladimir Vigdorovich, Nicholas Dambrauskas, Sneh Lata Gupta, Irene Gonzalez, Jose Luis Martinez, Stefan Slamanig, D. Noah Sather, Rama Raghunandan, Ponthip Wirachwong, Sant Muangnoicharoen, Punnee Pitisuttithum, Jens Wrammert, Mehul S. Suthar, Weina Sun, Peter Palese, Adolfo Garcia-Sastre, Viviana Simon, and Florian Krammer

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    The increasing usage of GEOSCAN online analysis in phosphate processing, Luke Balzan

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    The influence of energy output and substitution on the environmental impact of waste‐to‐energy operations, Lizzie Boakes

     

    The multidimensional evolution of ICB: New concepts, technology, and therapeutic modalities, Konstantin Konstantinov

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    The next generation of fibroblast-based vaccine development, Anna-Barbara Hachmann, Megan Pajak-Lee, David Klinkenberg, Andrew M. Campbell, Aneg L. Cortes, and Isabel M. Gimeno

     

    The restructuring of grain boundaries at the surfaces of meals, John J. Boland and Xiaopu Zhang

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    Thermal ablation behaviour of ultra-high temperature ceramic matrix composites made by RF enhanced chemical vapour infiltration, Jon Binner and Vinothini Venkatachalam

     

    Thermal activation of plasticity in BCC materials investigated by cryo-micropillar compression, Carl F. Kusche, Martin Heller, Jain Manish, James S. K.-L. Gibson, Jakob Schwiedrzik, Johann Michler, and Sandra Korte-Kerzel

     

    Thermal Barrier Coatings on Additive Manufactured Superalloy Parts, Nicolaie Markocsan

     

    Thermal Environmental Barrier Coatings (TEBCs), and their deposits-induced degradation and Its mitigation, Christopher Louzon and Nitin P. Padture

     

    Thermochemical stability of high entropy rare earth oxide (HERO) coatings for refractory alloys, Kristyn Ardrey, Elizabeth Opila, Bicheng Zhou, Prasanna Balachandran, Patrick Hopkins, Carolina Tallon, and Jonathan Laurer

     

    Thermodynamic and experimental SiC-ZrC CVD process development, Benjamin Lam, Jake McMurray, Ercan Cakmak, Michael Lance, and David Mitchell

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    Thermo-mechanical Analysis of Blister Damage in Eb-pvd Tbc System: Experiments and Modeling, Vincent Maurel, Lara Mahfouz, Vincent Guipont, Alain Köster, Basile Marchand, and Florent Coudon

     

    The Role of Digitalization in the Continuous Integrated Manufacturing of Therapeutic Proteins, Massimo Morbidelli

     

    The role of NIIMBL to advance manufacturing for Cell and Gene Therapy treatments, Barry Buckland

     

    The run of mine grade is on target but the process plant is underperforming – what’s the problem?, Ewan Wingate, Michael Kelahan, and Henry Lamb

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    The science behind the integrity of single-use system: Investigating liquid leak and microbial ingress mechanisms to determine the maximum allowable leakage limit, Nathalie Pathier, Marc Hogreve, Anilkumar Paramathma, Tomasz Urbania, and Marie-Christine Menier

     

    The Synthesis of EBC Layer Stacks by the Combination of PVD and CVD in a Continuous Vacuum Process, Jurgen Ramm, Dianying Chen, Max Döbeli, Kerstin Glaentz, Sébastien Guimond, Xavier Maeder, Helmut Schoech, and Benno Widrig

     

    The use of machine learning to navigate the sequence-activity landscape during directed evolution campaigns, Oscar Alvizo

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    The utilization of laser thermal testing with thermographic measurement for TBC lifetime performance evaluation, Zdeněk Veselý, Milan Honner, Matěj Hruška, and Petra Honnerová

     

    The zeta phase in the transition metal carbides and nitrides: Structure, microstructure and properties, Christopher R. Weinberger, Hang Yu, Xiao-Xiang Yu, and Gregory Thompson

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    This is our shot - new measures of vaccine infectivity, Johanna Bacher

     

    Three-dimensional characterization of damage in dual phase steels with deep learning, Setareh Medghalchi, Ehsan Karimi, Ulrich Kerzel, and Sandra Korte-Kerzel

     

    Tight controlled scalable Perfusion-SUBs from 250 ml and up, Per Stobbe

     

    Toward engineering an efficient and thermostable α-Amino Ester Hydrolase (AEH): Minimizing substrate inhibition and deactivation for continuous production of cephalexin, Colton Lagerman

     

    Towards an integrated bioprocess for scalable production and isolation of MSC- derived extracellular vesicles for cardiac repair, Marta Costa, António Xavier, Margarida Costa, Enrique Oltra, and Medical Research

     

    Towards an integrated continuous manufacturing process of adeno- associated virus (AAVs), João Mendes, Ricardo J.S. Silv, Cristina Peixoto, António Roldão, and Manuel J.T. Carrondo

     

    Towards a platform process for the manufacture of glycoconjugate vaccines for pneumococcal disease, Dr. Michael Sulu, Neha Patel, Dr. Emily Kay, Dr. Jon Cuccui, and Dr. Frank Baganz

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    Towards a platform process for the manufacture of glycoconjugate vaccines for pneumococcal disease, Frank Baganz, Neha Patel, Emily Kay, Jon Cuccui, Tarit Mukhopadhyay, and Michael Sulu

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    Towards a virus production platform based on VeroS cells grown on chemically defined media, Samia Rourou and Ikram Ben Marzouk

     

    Towards complex component manufacture via 3D printing and joining of parts, Iuliia S Elizarova and Luc J Vandeperre

     

    Towards engineering an efficient and thermostable α-amino ester hydrolase (AEH): Minimizing substrate inhibition and deactivation for continuous production of cephalexin, Colton Lagerman, Martha A. Grover, Ronald W. Rousseau, and Andreas S. Bommarius

     

    Towards implementation of novel single-use devices in integrated processes for biopharmaceuticals, Marina Y. Linova; Edite M. Tiago Gomes Martins; Dan N. Pham; Jinxin Fan; Sobhana A. Sripada; Stefano Menegatti,; Ruben G. Carbonell; and John M. Woodley

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    Towards updatable, multivalent Covid vaccines: A platform process to produce trimeric spike protein of SARS-COV-2 variants expressed in HEK293 stable cell clones, Renata G.F. Alvim, Tulio M. Lima, Federico F. Marsili, and Leda R. Castilho

     

    Transcriptomics and modelling to understand the benefits of low perfusion rate, Meeri Mäkinen, Hubert Schwarz, Veronique Chotteau, Johan Rockberg, Markella Zacharouli, and Magnus Lundqvist

     

    Transitioning cell-based processes towards scalable production, Isobelle Espiritu, Hanna Rasby, Emily Benz, Kelly Kemp, and Sebastian Rieck

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    Treating microbial systems engineering as an inverse function problem to enhance production of biomolecules, Ranjan Srivastava

     

    Truly continuous downstream processing of antibodies, overcoming bottlenecks, Gabriele Recanati; Patrick Scheidl; Magdalena Pappenreiter; Bernhard , Sissolak; and Alois Jungbauer

     

    TUBA Nova - A novel industrial EB-PVD coater platform for state-of-the-art TBCs and multi-layer coatings, Carsten Deus, Lutz Gottsmann, Steffen Berger, Susann Puppe, Anika Himmler, and Martin Seifert

     

    Tungsten diboride for high energy nuclear applications, James Davidson, Samuel Humphry-Baker, and Katharina Marquardt

     

    Two photon lithography for synthesis of fracture mechanical specimen, Alexander Jelinek, Markus Alfreider, Stanislav Zak, and Daniel Kiener

     

    Two small-scale perfusion models for the ambr250 to enable the study of production stability, Sarah Harcum and Srikanth Rapala

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    UHTC coatings obtained by plasma spraying: Characterization and oxidation behavior, Arthur Charrue, Marianne Balat-Pichelin, Aurélie Quet, and Charlotte Gregis

     

    Ultra-high temperature ceramics for transpiration cooling applications in hypersonic vehicles, Matthew McGilvray; Tobias Hermann; Hassan Saad Ifti,; Kharthik Chakravarthy; Marc Ewenz Rocher; Benjamin Williams; Luc Vandeperre; Rowan Hedgecock; Fabian Hufgard; and Stefan Lӧhle

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    Ultra-high temperature ceramics with exceptional strength at elevated temperature, Laura Silvestroni, Nicola Gilli, Diletta Sciti, Jeremy Watts, and William Fahrenholtz

     

    Uncovering exceptional micro-scale plasticity accommodation mechanisms in amorphous aluminum oxide through experimental and simulation results, Gaurav Mohanty, Erkka Frankberg, Janne Kalikka, Aloshious Lambai, Turkka Salminen, Sergei Khakalo, Matteo Vanazzi, Fabio Di Fonzi, Boris Paladino, and Erkki Levänen

     

    Understanding factors that cause product retention and fouling of hollow fiber filters in intensified perfusion processes, Sri Madabhushi, Qianying Zuo, Karthik Jayapal, and Tomas Kasza

     

    Understanding garnet phase stability in Gd/Y/Yb-CMAS systems and influences on multiphase T/EBC-CMAS interactions, Eeshani Paresh Godbole, Carlos G. Levi, Andrew R. Ericks, Collin S. Holgate, Frank W. Zok, and David L. Poerschke

     

    Understanding garnet phase stability in Gd/Y/Yb-CMAS systems and influences on multiphase T/EBC-CMAS interactions, Eeshani Paresh Godbole and David Poerschke

     

    Understanding Silicate Deposit Variability and its Implications for Evaluating TBCs and EBCs, Andrew Ericks, Carlos G. Levi, Collin S. Holgate, Frank W. Zok, and David L. PoerschkePlease click Additional Files below to see the full abstract.

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    Unfolded protein response biosensors for recombinant protein expression, Helena Godon, Sonakshi De, Núria Adelantado, Christoph Kiziak, Brigitte Gasser, and Diethard Mattanovich

     

    UNICAN: Dual capability in single use bioreactors, Ekta Mahajan

     

    Unlocking the key to successful commercialization by coupling the power of biocatalysis, strain engineering, and application studies, Khin Oo; Tatsuya Fukushima; Wenhua Lu,; Shirley (Xiyun) Zhang; Goutami Banerjee; and Janet (Jie) Yang

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    Unraveling acetogen gas fermentation using quantitative systems biology, Kaspar Valgepea, Renato d.S.P. Lemgruber, Vishnuvardhan Mahamkali, Kieran Meaghan, Gert Talbo, Robin W. Palfreyman, Ricardo Axayacatl Gonzalez Garcia, Nobuaki Takemori, Ayako Takamori, Christopher de Bakker, Christina Ludwig, Tanus Abdalla, Björn Heijstra, James B. Behrendorff, Alexander P. Mueller, Ryan Tappel, Séan D. Simpson, Michael Köpke, Lars K. Nielsen, and Esteban Marcellin

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    Untangling the pro-fibrotic loop in pulmonary fibrosis: Synergy between substrate stiffness and soluble factors promotes alternative activation of macrophages, Catherine Fromen

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    Unveiling process knowledge for plasmid DNA fermentation across upstream scales, Amélie Boulais and Lara Nascimento-Brooks

     

    Unveiling the mechanisms of motion of synchro-Shockley dislocations in Laves phases, Zhuocheng Xie, Dimitri Chauraud, Achraf Atila, Erik Bitzek, and Sandra Korte-Kerzel

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    Upstream process optimization to support efficient HEK293 cell growth and adenovirus production, Syed Muaz Khalil, Wen-Yang Tsai, and Anna-Barbara Hachmann

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    Use of a parallel bioreactor scaledown system for optimisation of a perfusion-based upstream process for adenovirus production, Carina C.D. Joe, Steffi Scholze, Julia Niemann, and Alexander D. Douglas

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    Use of Genome-scale Models to get new insights into the MarineActinomycete genus Salinispora: Microbial engineering and its application in secondary metabolite production, Barbara A. Andrews, Carolina A. Contador, and Juan A. Asenjo

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    Use of sulfated-cellulose membrane adsorbers to intensify purification of cell culturederived influenza A and B viruses, Amélie Boulais, Ricarda Busse, and A. Raquel Fortuna

     

    Using machine learning to improve protein function, Andrew Ellington

     

    Using small-scale mechanics to probe the origins of segregation-induced strengthening, Mohammed Kamran Bhat, Prithiv Thoudden Sukumar, Lena Frommeyer, Gerhard Dehm, and James P. Best

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    Vaccine manufacturing capacity expansion – An approach to meet global needs based on Covid-19 learnings, Julia Kuhn

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    Valorization of renewables into bio-based chemicals using metabolically engineered microbes, Christoph Wittmann

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    Vasculature-on-a-chip platform with innate immunity enables identification of angiopoietin-1 derived peptide as a therapeutic for SARS-CoV-2 induced inflammation, Rick Xing Ze Lu, Benjamin Fook Lun Lai, Naimeh Rafatian, Dakota Gustafson, Scott B. Campbell, Arinjay Banerjee, Karren Mossman, Robert Kozak, Samira Mubareka, Kathryn L. Howe, Jason E. Fish, and Milica Radisic

     

    Viability enrichment of final drug product using counter-flow centrifugation, Jonathan Lim, Christine Cezar, Ivie Aifuwa, and Vincent Couming

     

    Virtual reality to rapidly scale a resilient workforce for cell and gene therapy manufacturing, Ivan Wall

     

    Virus-Free CRISPR CAR T cells induce solid tumor regression, Lauren Sarko, Katherine P. Mueller, Nicole J. Piscopo, Matthew H. Forsberg, Louise A. Saraspe, Amritava Das, Brittany Russell, Madeline Smerchansky, Lei Shi, Adeela Ali, Cicera R. Lazzarotto, Shengdar Q. Tsai, Christian M. Capitini, and Krishanu Saha

     

    Virus-Free CRISPR CAR T cells induce solid tumor regression, Lauren E. Sarko, Katherine P. Mueller, Nicole J. Piscopo, Matthew H. Forsberg, Louise A. Saraspe, Amritava Das, Brittany Russell, Madeline Smerchansky, Lei Shi, Adeela Ali, Cicera R. Lazzarotto, Shengdar Q. Tsai, Christian M. Capitini, and Krishanu Saha

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    Virus like particles expressed in insect cells and mammalian cells as a plataform for the development of a Zika vaccine, Selene J. Uribe, Ana Ruth Pastor, Diego Fontana, Claudio Prieto, Octavio T. Ramírez, and Laura A. Palomares

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    We don't talk about neutrophils: Novel particle-based approach to immunomodulation in acute inflammatory diseases, Lola Eniola-Adefeso

     

    Why do we still need LCA-modelling in waste management?, Thomas Christensen

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    Workshop: Innovation in Global Health, Birgitte Giersing and Marion Menozzi-Amaud

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    Workshop: Process intensification considerations for LMIC, Philippe Alexandre Gilbert

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    Yarrowia lipolytica as a chassis for isoprenoid production, Aleksander Kruis, Peter Panjan, Tilen Konte, Gregor Kosec, and Tadej Markuš

     

    Ytterbium silicate environmental barrier coatings prepared by a novel slurry spraying- reactive sintering technique, Gauri Waghmare and Ashutosh S. . Gandhi

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    Zirconium Carbide Oxidation and Passivation for Nuclear Fuel Applications, Allison Rzepka, Matthew Konnik, Francesco Panerai, Collin Foster, Kelly A. Stephani, and Daniel H. Hecht

 
 
 

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